Murcko scaffold
1-Benzylaziridine scaffold
67 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 67
- With full pages
- 5
Scaffold SMILES
c1ccc(CN2CC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 67 chemicals
alpha-Methyl-beta-phenyl-1-aziridineethanol
CAS 91245-83-9C11H15NO
1-Benzylaziridine
CAS 1074-42-6C9H11N
1-Aziridineethanol, beta-phenyl-
CAS 2421-11-6C10H13NO
1-(alpha-(Dimethylamino)benzyl)aziridine
CAS 4025-26-7C11H16N2
1-(alpha-(Diethylamino)benzyl)-2,2-dimethylaziridine
CAS 20030-88-0C15H24N2
1-Benzylaziridine-2-carboxamide
CAS 35216-54-7C10H12N2O
![Methyl 3-[4-(aziridin-1-ylmethyl)phenyl]propanoate chemical structure, C13H17NO2, CAS 7505-48-8](/s/AAPRBKBSYHZEHJ-UHFFFAOYSA-N.svg)
Methyl 3-[4-(aziridin-1-ylmethyl)phenyl]propanoate
CAS 7505-48-8C13H17NO2
Methyl 3-(aziridin-1-yl)-3-phenylpropanoate
CAS 22482-11-7C12H15NO2
1-Benzyl-2,2,3-trifluoro-3-(trifluoromethyl)aziridine
CAS 5585-30-8C10H7F6N
1-Benzyl-2,3-difluoro-2,3-bis(trifluoromethyl)aziridine
CAS 5321-09-5C11H7F8N
Methyl 1-benzylaziridine-2-carboxylate
CAS 21384-53-2C11H13NO2
1-Benzyl-2-(trifluoromethyl)aziridine
CAS 106240-89-5C10H10F3N
1-Benzyl-2-tert-butyl-3-methylaziridine
CAS 55712-34-0C14H21N
2-Aziridinemethanol, 1-(phenylmethyl)-
CAS 63226-81-3C10H13NO
2-Aziridinemethanol, 3-methyl-1-(phenylmethyl)-
CAS 99858-54-5C11H15NO
![(2S)-1-[(1R)-1-Phenylethyl]aziridine-2-carboxamide chemical structure, C11H14N2O, CAS 75985-51-2](/s/PUPRTGJZBLTWDQ-KMDCHFIWSA-N.svg)
(2S)-1-[(1R)-1-Phenylethyl]aziridine-2-carboxamide
CAS 75985-51-2C11H14N2O
![[(2S)-1-[(1R)-1-Phenylethyl]aziridin-2-yl]methanol chemical structure, C11H15NO, CAS 173143-73-2](/s/BMEHDCBKAUDFBH-BVAQLPTGSA-N.svg)
[(2S)-1-[(1R)-1-Phenylethyl]aziridin-2-yl]methanol
CAS 173143-73-2C11H15NO
RefChem:381335
CAS 173034-70-3C11H15NO
![(2R)-1-[(1R)-1-Phenylethyl]aziridine-2-carboxamide chemical structure, C11H14N2O, CAS 75985-52-3](/s/PUPRTGJZBLTWDQ-SQMUNVKPSA-N.svg)
(2R)-1-[(1R)-1-Phenylethyl]aziridine-2-carboxamide
CAS 75985-52-3C11H14N2O
![Aziridine, 2-(bromomethyl)-1-[(4-methylphenyl)methyl]- chemical structure, C11H14BrN, CAS 156697-63-1](/s/HEYMNIGZOOJQSW-UHFFFAOYSA-N.svg)
Aziridine, 2-(bromomethyl)-1-[(4-methylphenyl)methyl]-
CAS 156697-63-1C11H14BrN
![Aziridine, 2-(bromomethyl)-1-[(4-chlorophenyl)methyl]- chemical structure, C10H11BrClN, CAS 156697-68-6](/s/SGQHDNSRLLJRAO-UHFFFAOYSA-N.svg)
Aziridine, 2-(bromomethyl)-1-[(4-chlorophenyl)methyl]-
CAS 156697-68-6C10H11BrClN
(R)-1-Benzyl-2-(trifluoromethyl)aziridine
CAS 198019-15-7C10H10F3N
![Thiocyanic acid, [1-[(2-bromophenyl)methyl]-2-aziridinyl]methyl ester chemical structure, C11H11BrN2S, CAS 832724-81-9](/s/UTKNXYKBUQIBAZ-UHFFFAOYSA-N.svg)
Thiocyanic acid, [1-[(2-bromophenyl)methyl]-2-aziridinyl]methyl ester
CAS 832724-81-9C11H11BrN2S
1-Benzyl-2-isopropylaziridine
CAS 263262-57-3C12H17N
- Aziridine, 2-(bromomethyl)-1-[(2-chlorophenyl)methyl]-832724-77-3C10H11BrClN
- Thiocyanic acid, [1-(phenylmethyl)-2-aziridinyl]methyl ester832724-78-4C11H12N2S
- Thiocyanic acid, [1-[(2-chlorophenyl)methyl]-2-aziridinyl]methyl ester832724-82-0C11H11ClN2S
- 1-Benzyl-2-(bromomethyl)aziridine25662-24-2C10H12BrN
- Ethyl 1-[(S)-1-phenylethyl]aziridine-(R)-carboxylate68820-71-3C13H17NO2
- 2-(Bromomethyl)-1-[(3-methoxyphenyl)methyl]aziridine832724-75-1C11H14BrNO
- Thiocyanic acid, [1-[(4-methoxyphenyl)methyl]-2-aziridinyl]methyl ester832724-79-5C12H14N2OS
- Aziridine, 2-(bromomethyl)-1-[(2-bromophenyl)methyl]-832724-76-2C10H11Br2N
- Ethyl 1-benzylaziridine-2-carboxylate34943-06-1C12H15NO2
- Thiocyanic acid, [1-[(3-methoxyphenyl)methyl]-2-aziridinyl]methyl ester832724-80-8C12H14N2OS
- Aziridine, 2-ethyl-1-[(1R)-2-methoxy-1-phenylethyl]-, (2S)-(9CI)514168-46-8C13H19NO
- Aziridine, 2,2-dimethyl-1-(phenylmethyl)-3-(2-propenyl)-831200-96-5C14H19N
- Aziridine, 2-methyl-1-(phenylmethyl)-2-(2-propenyl)-831201-02-6C13H17N
- (S)-(+)-1-Benzyl-2-methylaziridine34260-34-9C10H13N
- (S)-1-Benzyl-2-ethylaziridine59573-39-6C11H15N
- 2-Aziridinemethanol, 1-[(1S)-1-phenylethyl]-, (2R)-245362-53-2C11H15NO
- (2R)-1-((1S)-1-Phenylethyl)-2-aziridinecarboxaldehyde182370-58-7C11H13NO
- (2S,3S)-1-Benzyl-3-(trifluoromethyl)aziridine-2-carboxylic acid2641825-62-7C11H10F3NO2
- 1-Benzyl-N,N-diethylaziridine-2-sulfonamide87975-53-9C13H20N2O2S
- 1-Benzyl-N-ethylaziridine-2-sulfonamide87975-57-3C11H16N2O2S
- 1-(1-Phenylethyl)aziridine62626-90-8C10H13N
- 1-{[3-(Trifluoromethyl)phenyl]methyl}aziridine-2-carbonitrile75985-37-4C11H9F3N2
- 1-[(2-Chlorophenyl)methyl]aziridine-2-carbonitrile75985-44-3C10H9ClN2
- 1-[(4-Methylphenyl)methyl]aziridine-2-carbonitrile75985-11-4C11H12N2
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(CC2CC2)cc1130 chemicals
c1ccc(OC2CC2)cc157 chemicals
O=C(c1ccccc1)C1CC128 chemicals
c1ccc(NC2CC2)cc120 chemicals
c1ccc(CC2CO2)cc114 chemicals
c1ccc(SC2CC2)cc114 chemicals
C1COCC(CC2CO2)C111 chemicals
O=S(=O)(c1ccccc1)C1CC110 chemicals
c1ccc(NC2CC2)nc110 chemicals
C1CCN(CC2CC2)CC19 chemicals
O=C(C1CC1)N1CCNCC17 chemicals
c1cncc(OC2CC2)c17 chemicals