CompoundList
Sign in
Murcko scaffold

1-(Piperidin-4-yl)pyrrolidin-2-one scaffold

56 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
56
With full pages
5
Scaffold SMILES

O=C1CCCN1C1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Piperidin-4-yl)pyrrolidin-2-one page
Murcko scaffold O=C1CCCN1C1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 56 chemicals

1-(Piperidin-4-yl)pyrrolidin-2-one chemical structure, C9H16N2O, CAS 91596-61-1
1-(Piperidin-4-yl)pyrrolidin-2-one
CAS 91596-61-1C9H16N2O
tert-Butyl 4-[4-(methoxycarbonyl)-2-oxo-1-pyrrolidinyl]tetrahydro-1(2H)-pyridinecarboxylate chemical structure, C16H26N2O5, CAS 937601-48-4
tert-Butyl 4-[4-(methoxycarbonyl)-2-oxo-1-pyrrolidinyl]tetrahydro-1(2H)-pyridinecarboxylate
CAS 937601-48-4C16H26N2O5
1-[1-(tert-Butoxycarbonyl)-4-piperidinyl]-5-oxo-3-pyrrolidinecarboxylic acid chemical structure, C15H24N2O5, CAS 937601-51-9
1-[1-(tert-Butoxycarbonyl)-4-piperidinyl]-5-oxo-3-pyrrolidinecarboxylic acid
CAS 937601-51-9C15H24N2O5
1-(Piperidin-4-yl)pyrrolidin-2-one hydrochloride chemical structure, C9H17ClN2O, CAS 548769-02-4
1-(Piperidin-4-yl)pyrrolidin-2-one hydrochloride
CAS 548769-02-4C9H17ClN2O
1-[1-(Ethoxycarbonyl)piperidin-4-yl]-5-oxopyrrolidine-3-carboxylic acid chemical structure, C13H20N2O5, CAS 1016840-28-0
1-[1-(Ethoxycarbonyl)piperidin-4-yl]-5-oxopyrrolidine-3-carboxylic acid
CAS 1016840-28-0C13H20N2O5
(S)-3-Hydroxy-1-piperidin-4-YL-pyrrolidin-2-one chemical structure, C9H16N2O2, CAS 1253792-24-3
(S)-3-Hydroxy-1-piperidin-4-YL-pyrrolidin-2-one
CAS 1253792-24-3C9H16N2O2
1-(1-Methylpiperidin-4-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C11H18N2O3, CAS 933691-56-6
1-(1-Methylpiperidin-4-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 933691-56-6C11H18N2O3
4-Amino-1-(1-methylpiperidin-4-yl)pyrrolidin-2-one chemical structure, C10H19N3O, CAS 1155572-75-0
4-Amino-1-(1-methylpiperidin-4-yl)pyrrolidin-2-one
CAS 1155572-75-0C10H19N3O
4-Hydroxy-1-piperidin-4-YL-pyrrolidin-2-one chemical structure, C9H16N2O2, CAS 941672-66-8
4-Hydroxy-1-piperidin-4-YL-pyrrolidin-2-one
CAS 941672-66-8C9H16N2O2
N-(1-Hydroxy-2-methylpropan-2-yl)-5-oxo-1-(piperidin-4-yl)pyrrolidine-3-carboxamide chemical structure, C14H25N3O3, CAS 1263285-15-9
N-(1-Hydroxy-2-methylpropan-2-yl)-5-oxo-1-(piperidin-4-yl)pyrrolidine-3-carboxamide
CAS 1263285-15-9C14H25N3O3
tert-Butyl 4-[4-[(1-hydroxy-2-methylpropan-2-yl)carbamoyl]-2-oxopyrrolidin-1-yl]piperidine-1-carboxylate chemical structure, C19H33N3O5, CAS 1221278-48-3
tert-Butyl 4-[4-[(1-hydroxy-2-methylpropan-2-yl)carbamoyl]-2-oxopyrrolidin-1-yl]piperidine-1-carboxylate
CAS 1221278-48-3C19H33N3O5
Methyl 5-oxo-1-(piperidin-4-yl)pyrrolidine-3-carboxylate chemical structure, C11H18N2O3, CAS 1211594-35-2
Methyl 5-oxo-1-(piperidin-4-yl)pyrrolidine-3-carboxylate
CAS 1211594-35-2C11H18N2O3
3-Hydroxy-1-(4-piperidyl)pyrrolidin-2-one chemical structure, C9H16N2O2
3-Hydroxy-1-(4-piperidyl)pyrrolidin-2-one
C9H16N2O2
1-(1-Acetylpiperidin-4-yl)pyrrolidin-2-one chemical structure, C11H18N2O2, CAS 1421506-09-3
1-(1-Acetylpiperidin-4-yl)pyrrolidin-2-one
CAS 1421506-09-3C11H18N2O2
3-Amino-1-(1-methylpiperidin-4-yl)pyrrolidin-2-one chemical structure, C10H19N3O, CAS 1251225-28-1
3-Amino-1-(1-methylpiperidin-4-yl)pyrrolidin-2-one
CAS 1251225-28-1C10H19N3O
tert-Butyl 4-(3-hydroxy-2-oxopyrrolidin-1-yl)piperidine-1-carboxylate chemical structure, C14H24N2O4, CAS 1824550-20-0
tert-Butyl 4-(3-hydroxy-2-oxopyrrolidin-1-yl)piperidine-1-carboxylate
CAS 1824550-20-0C14H24N2O4
tert-Butyl 4-(3-bromo-2-oxopyrrolidin-1-yl)piperidine-1-carboxylate chemical structure, C14H23BrN2O3, CAS 1351168-97-2
tert-Butyl 4-(3-bromo-2-oxopyrrolidin-1-yl)piperidine-1-carboxylate
CAS 1351168-97-2C14H23BrN2O3
4-(2-Oxopyrrolidin-1-yl)piperidine-1-carboxamide chemical structure, C10H17N3O2, CAS 2408971-98-0
4-(2-Oxopyrrolidin-1-yl)piperidine-1-carboxamide
CAS 2408971-98-0C10H17N3O2
4-Hydroxy-1-(piperidin-4-yl)pyrrolidin-2-one hydrochloride chemical structure, C9H17ClN2O2, CAS 1237840-39-9
4-Hydroxy-1-(piperidin-4-yl)pyrrolidin-2-one hydrochloride
CAS 1237840-39-9C9H17ClN2O2
1-(1-Methylpiperidin-4-yl)-5-oxopyrrolidine-3-carboxylic acid hydrate chemical structure, C11H20N2O4, CAS 1396886-98-8
1-(1-Methylpiperidin-4-yl)-5-oxopyrrolidine-3-carboxylic acid hydrate
CAS 1396886-98-8C11H20N2O4
1-[1-(2-Methoxyacetyl)piperidin-4-yl]pyrrolidin-2-one chemical structure, C12H20N2O3, CAS 1421463-76-4
1-[1-(2-Methoxyacetyl)piperidin-4-yl]pyrrolidin-2-one
CAS 1421463-76-4C12H20N2O3
1-(1-(2-Ethoxyacetyl)piperidin-4-yl)pyrrolidin-2-one chemical structure, C13H22N2O3, CAS 1421497-56-4
1-(1-(2-Ethoxyacetyl)piperidin-4-yl)pyrrolidin-2-one
CAS 1421497-56-4C13H22N2O3
5-Oxo-1-(piperidin-4-yl)pyrrolidine-3-carboxylic acid chemical structure, C10H16N2O3, CAS 933714-25-1
5-Oxo-1-(piperidin-4-yl)pyrrolidine-3-carboxylic acid
CAS 933714-25-1C10H16N2O3
5-Oxo-1-(piperidin-4-yl)pyrrolidine-3-carboxylic acid hydrochloride chemical structure, C10H17ClN2O3, CAS 1461714-48-6
5-Oxo-1-(piperidin-4-yl)pyrrolidine-3-carboxylic acid hydrochloride
CAS 1461714-48-6C10H17ClN2O3