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Murcko scaffold

1-(Piperidin-4-yl)pyrrolidin-2-one scaffold

56 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
56
With full pages
5
Scaffold SMILES

O=C1CCCN1C1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Piperidin-4-yl)pyrrolidin-2-one page
Murcko scaffold O=C1CCCN1C1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 56 of 56 chemicals

4-Methoxy-1-(piperidin-4-yl)pyrrolidin-2-one hydrochloride chemical structure, C10H19ClN2O2, CAS 2460755-39-7
4-Methoxy-1-(piperidin-4-yl)pyrrolidin-2-one hydrochloride
CAS 2460755-39-7C10H19ClN2O2
4-Methoxy-1-(piperidin-4-yl)pyrrolidin-2-one chemical structure, C10H18N2O2, CAS 2460749-64-6
4-Methoxy-1-(piperidin-4-yl)pyrrolidin-2-one
CAS 2460749-64-6C10H18N2O2
5-Oxo-1-(1-prop-2-enoylpiperidin-4-yl)pyrrolidine-3-carboxylic acid chemical structure, C13H18N2O4, CAS 2567498-76-2
5-Oxo-1-(1-prop-2-enoylpiperidin-4-yl)pyrrolidine-3-carboxylic acid
CAS 2567498-76-2C13H18N2O4
3-Hydroxy-1-(piperidin-4-yl)pyrrolidin-2-one hydrochloride chemical structure, C9H17ClN2O2, CAS 2641694-35-9
3-Hydroxy-1-(piperidin-4-yl)pyrrolidin-2-one hydrochloride
CAS 2641694-35-9C9H17ClN2O2
2-Oxo-1-(piperidin-4-yl)pyrrolidine-3-carboxylic acid chemical structure, C10H16N2O3, CAS 2138428-04-1
2-Oxo-1-(piperidin-4-yl)pyrrolidine-3-carboxylic acid
CAS 2138428-04-1C10H16N2O3
1-(1-Nitrosopiperidin-4-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C10H15N3O4, CAS 2624125-18-2
1-(1-Nitrosopiperidin-4-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 2624125-18-2C10H15N3O4
5-Oxo-1-[1-(2,2,2-trifluoroacetyl)piperidin-4-yl]pyrrolidine-3-carboxylic acid chemical structure, C12H15F3N2O4, CAS 2680739-64-2
5-Oxo-1-[1-(2,2,2-trifluoroacetyl)piperidin-4-yl]pyrrolidine-3-carboxylic acid
CAS 2680739-64-2C12H15F3N2O4
3-Bromo-1-(piperidin-4-yl)pyrrolidin-2-one chemical structure, C9H15BrN2O, CAS 2757927-22-1
3-Bromo-1-(piperidin-4-yl)pyrrolidin-2-one
CAS 2757927-22-1C9H15BrN2O