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Murcko scaffold

Ring system with 2 rings and 13 atoms

38 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
38
With full pages
14
Scaffold SMILES

O=C(c1ccccc1)N1C=NCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)N1C=NCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 38 of 38 chemicals

Ketone, 2-methyl-2-imidazolin-1-yl 3,4,5-trimethoxyphenyl- chemical structure, C14H18N2O4, CAS 50916-04-6
Ketone, 2-methyl-2-imidazolin-1-yl 3,4,5-trimethoxyphenyl-
CAS 50916-04-6C14H18N2O4
(4-Chlorophenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C11H11ClN2OS, CAS 673476-85-2
(4-Chlorophenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 673476-85-2C11H11ClN2OS
(3,4-Diethoxyphenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C15H20N2O3S, CAS 851863-19-9
(3,4-Diethoxyphenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851863-19-9C15H20N2O3S
(2-Chloro-6-fluorophenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C11H10ClFN2OS, CAS 851863-30-4
(2-Chloro-6-fluorophenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851863-30-4C11H10ClFN2OS
(2-(Methylthio)-4,5-dihydro-1H-imidazol-1-yl)(3,4,5-triethoxyphenyl)methanone chemical structure, C17H24N2O4S, CAS 851863-21-3
(2-(Methylthio)-4,5-dihydro-1H-imidazol-1-yl)(3,4,5-triethoxyphenyl)methanone
CAS 851863-21-3C17H24N2O4S
(2-Ethoxyphenyl)-(2-methylsulfanyl-4,5-dihydroimidazol-1-yl)methanone chemical structure, C13H16N2O2S, CAS 851863-10-0
(2-Ethoxyphenyl)-(2-methylsulfanyl-4,5-dihydroimidazol-1-yl)methanone
CAS 851863-10-0C13H16N2O2S
(3,4-Dimethoxyphenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C13H16N2O3S, CAS 851863-15-5
(3,4-Dimethoxyphenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851863-15-5C13H16N2O3S
(2-Methylsulfanyl-4,5-dihydroimidazol-1-yl)-[3-(trifluoromethyl)phenyl]methanone chemical structure, C12H11F3N2OS, CAS 851863-37-1
(2-Methylsulfanyl-4,5-dihydroimidazol-1-yl)-[3-(trifluoromethyl)phenyl]methanone
CAS 851863-37-1C12H11F3N2OS
(3-Bromophenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C11H11BrN2OS, CAS 851863-25-7
(3-Bromophenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851863-25-7C11H11BrN2OS
(4-Butoxyphenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C15H20N2O2S, CAS 851863-13-3
(4-Butoxyphenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851863-13-3C15H20N2O2S
(2-Methyl-3-nitrophenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C12H13N3O3S, CAS 851863-35-9
(2-Methyl-3-nitrophenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851863-35-9C12H13N3O3S
N,N-Diethyl-4-(2-(methylthio)-4,5-dihydro-1H-imidazole-1-carbonyl)benzenesulfonamide chemical structure, C15H21N3O3S2, CAS 851863-57-5
N,N-Diethyl-4-(2-(methylthio)-4,5-dihydro-1H-imidazole-1-carbonyl)benzenesulfonamide
CAS 851863-57-5C15H21N3O3S2
(2-(Methylthio)-4,5-dihydro-1H-imidazol-1-yl)(2-nitrophenyl)methanone chemical structure, C11H11N3O3S, CAS 851863-32-6
(2-(Methylthio)-4,5-dihydro-1H-imidazol-1-yl)(2-nitrophenyl)methanone
CAS 851863-32-6C11H11N3O3S
(3-Methoxyphenyl)-(2-methylsulfanyl-4,5-dihydroimidazol-1-yl)methanone chemical structure, C12H14N2O2S, CAS 685127-11-1
(3-Methoxyphenyl)-(2-methylsulfanyl-4,5-dihydroimidazol-1-yl)methanone
CAS 685127-11-1C12H14N2O2S
(3,5-Dimethylphenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C13H16N2OS, CAS 851863-06-4
(3,5-Dimethylphenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851863-06-4C13H16N2OS
(4-Ethoxyphenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C13H16N2O2S, CAS 851863-11-1
(4-Ethoxyphenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851863-11-1C13H16N2O2S
N,N-Diethyl-4-(2-ethylsulfanyl-4,5-dihydroimidazole-1-carbonyl)benzenesulfonamide chemical structure, C16H23N3O3S2, CAS 862826-64-0
N,N-Diethyl-4-(2-ethylsulfanyl-4,5-dihydroimidazole-1-carbonyl)benzenesulfonamide
CAS 862826-64-0C16H23N3O3S2
(2,3-Dimethoxyphenyl)-(2-methylsulfanyl-4,5-dihydroimidazol-1-yl)methanone chemical structure, C13H16N2O3S, CAS 851863-16-6
(2,3-Dimethoxyphenyl)-(2-methylsulfanyl-4,5-dihydroimidazol-1-yl)methanone
CAS 851863-16-6C13H16N2O3S
(4-Methyl-3-nitrophenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C12H13N3O3S, CAS 851863-36-0
(4-Methyl-3-nitrophenyl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851863-36-0C12H13N3O3S
(4-Bromophenyl)-(2-methylsulfanyl-4,5-dihydroimidazol-1-yl)methanone chemical structure, C11H11BrN2OS, CAS 851863-27-9
(4-Bromophenyl)-(2-methylsulfanyl-4,5-dihydroimidazol-1-yl)methanone
CAS 851863-27-9C11H11BrN2OS
(3,4-Diethoxyphenyl)(2-(ethylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C16H22N2O3S, CAS 862826-59-3
(3,4-Diethoxyphenyl)(2-(ethylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 862826-59-3C16H22N2O3S
(2-(Ethylthio)-4,5-dihydro-1H-imidazol-1-yl)(phenyl)methanone chemical structure, C12H14N2OS, CAS 892474-49-6
(2-(Ethylthio)-4,5-dihydro-1H-imidazol-1-yl)(phenyl)methanone
CAS 892474-49-6C12H14N2OS
(2-(Ethylthio)-4,5-dihydro-1H-imidazol-1-yl)(4-(trifluoromethyl)phenyl)methanone chemical structure, C13H13F3N2OS, CAS 892476-74-3
(2-(Ethylthio)-4,5-dihydro-1H-imidazol-1-yl)(4-(trifluoromethyl)phenyl)methanone
CAS 892476-74-3C13H13F3N2OS
(2-(Methylthio)-4,5-dihydro-1H-imidazol-1-yl)(3-nitrophenyl)methanone chemical structure, C11H11N3O3S, CAS 851863-33-7
(2-(Methylthio)-4,5-dihydro-1H-imidazol-1-yl)(3-nitrophenyl)methanone
CAS 851863-33-7C11H11N3O3S