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Murcko scaffold

Ring system with 4 rings and 22 atoms

20 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
20
With full pages
2
Scaffold SMILES

c1ccc(-c2nc3ccccn3c2CN2CCCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2nc3ccccn3c2CN2CCCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

2-(4-Nitrophenyl)-3-(1-piperidinylmethyl)imidazo(1,2-a)pyridine chemical structure, C19H20N4O2, CAS 3323-00-0
2-(4-Nitrophenyl)-3-(1-piperidinylmethyl)imidazo(1,2-a)pyridine
CAS 3323-00-0C19H20N4O2
1-((6-Bromo-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid chemical structure, C20H19BrFN3O2, CAS 728916-77-6
1-((6-Bromo-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid
CAS 728916-77-6C20H19BrFN3O2
1-[2-(4-Bromophenyl)imidazo[1,2-A]pyridin-3-ylmethyl]piperidine-4-carboxylic acid chemical structure, C20H20BrN3O2, CAS 727977-54-0
1-[2-(4-Bromophenyl)imidazo[1,2-A]pyridin-3-ylmethyl]piperidine-4-carboxylic acid
CAS 727977-54-0C20H20BrN3O2
1-((6-Chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid chemical structure, C20H19ClFN3O2, CAS 728916-56-1
1-((6-Chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid
CAS 728916-56-1C20H19ClFN3O2
1-((6-Chloro-2-(3-methoxyphenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid chemical structure, C21H22ClN3O3, CAS 728916-52-7
1-((6-Chloro-2-(3-methoxyphenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid
CAS 728916-52-7C21H22ClN3O3
1-((6-Chloro-2-(4-methoxyphenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid chemical structure, C21H22ClN3O3, CAS 728916-50-5
1-((6-Chloro-2-(4-methoxyphenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid
CAS 728916-50-5C21H22ClN3O3
1-[2-(3,4-Dimethoxyphenyl)imidazo[1,2-A]pyridin-3-ylmethyl]piperidine-4-carboxylic acid chemical structure, C22H25N3O4, CAS 727977-51-7
1-[2-(3,4-Dimethoxyphenyl)imidazo[1,2-A]pyridin-3-ylmethyl]piperidine-4-carboxylic acid
CAS 727977-51-7C22H25N3O4
1-[2-(3,4-Dimethoxyphenyl)-6-methylimidazo[1,2-a]pyridin-3-ylmethyl]piperidine-4-carboxylic acid chemical structure, C23H27N3O4, CAS 886496-46-4
1-[2-(3,4-Dimethoxyphenyl)-6-methylimidazo[1,2-a]pyridin-3-ylmethyl]piperidine-4-carboxylic acid
CAS 886496-46-4C23H27N3O4
1-((2-(4-Fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid chemical structure, C20H20FN3O2, CAS 727977-52-8
1-((2-(4-Fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid
CAS 727977-52-8C20H20FN3O2
1-((2-(4-Fluorophenyl)-8-methylimidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid chemical structure, C21H22FN3O2, CAS 727977-66-4
1-((2-(4-Fluorophenyl)-8-methylimidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid
CAS 727977-66-4C21H22FN3O2
1-[[2-(3-Methoxyphenyl)imidazo[1,2-a]pyridin-3-yl]methyl]-4-piperidinecarboxylic acid chemical structure, C21H23N3O3, CAS 727977-50-6
1-[[2-(3-Methoxyphenyl)imidazo[1,2-a]pyridin-3-yl]methyl]-4-piperidinecarboxylic acid
CAS 727977-50-6C21H23N3O3
1-[2-(4-Methoxy-phenyl)-imidazo[1,2-a]pyridin-3-ylmethyl]-piperidine-4-carboxylic acid chemical structure, C21H23N3O3, CAS 727977-49-3
1-[2-(4-Methoxy-phenyl)-imidazo[1,2-a]pyridin-3-ylmethyl]-piperidine-4-carboxylic acid
CAS 727977-49-3C21H23N3O3
1-((8-Methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid chemical structure, C21H23N3O2, CAS 727977-57-3
1-((8-Methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid
CAS 727977-57-3C21H23N3O2
1-((2-Phenylimidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid chemical structure, C20H21N3O2, CAS 727977-47-1
1-((2-Phenylimidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid
CAS 727977-47-1C20H21N3O2
1-{[2-(4-Methylphenyl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-4-carboxylic acid chemical structure, C21H23N3O2, CAS 727977-55-1
1-{[2-(4-Methylphenyl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-4-carboxylic acid
CAS 727977-55-1C21H23N3O2
2-(4-Chlorophenyl)-3-(piperidinomethyl)imidazo[1,2-a]pyridine chemical structure, C19H20ClN3, CAS 861208-75-5
2-(4-Chlorophenyl)-3-(piperidinomethyl)imidazo[1,2-a]pyridine
CAS 861208-75-5C19H20ClN3
6-Chloro-2-(4-chlorophenyl)-3-(piperidinomethyl)imidazo[1,2-a]pyridine chemical structure, C19H19Cl2N3, CAS 861212-37-5
6-Chloro-2-(4-chlorophenyl)-3-(piperidinomethyl)imidazo[1,2-a]pyridine
CAS 861212-37-5C19H19Cl2N3
2-(4-Methoxyphenyl)-3-[(2-methyl-1-piperidinyl)methyl]imidazo[1,2-a]pyridin-6-amine chemical structure, C21H26N4O, CAS 1216920-43-2
2-(4-Methoxyphenyl)-3-[(2-methyl-1-piperidinyl)methyl]imidazo[1,2-a]pyridin-6-amine
CAS 1216920-43-2C21H26N4O
2-(4-Methoxy-3-nitrophenyl)-3-(1-piperidinylmethyl)imidazo[1,2-a]pyridin-6-amine chemical structure, C20H23N5O3, CAS 1216410-08-0
2-(4-Methoxy-3-nitrophenyl)-3-(1-piperidinylmethyl)imidazo[1,2-a]pyridin-6-amine
CAS 1216410-08-0C20H23N5O3
2-(4-Methylphenyl)-3-(1-piperidinylmethyl)imidazo[1,2-a]pyridin-6-amine chemical structure, C20H24N4, CAS 1219181-15-3
2-(4-Methylphenyl)-3-(1-piperidinylmethyl)imidazo[1,2-a]pyridin-6-amine
CAS 1219181-15-3C20H24N4