CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 22 atoms

74 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
74
With full pages
4
Scaffold SMILES

c1ccc(Cn2c(-c3cccnc3)nc3ccccc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cn2c(-c3cccnc3)nc3ccccc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 74 chemicals

1H-Benzimidazole, 1-((2,6-difluorophenyl)methyl)-4-methyl-2-(3-pyridinyl)- chemical structure, C20H15F2N3, CAS 199594-74-6
1H-Benzimidazole, 1-((2,6-difluorophenyl)methyl)-4-methyl-2-(3-pyridinyl)-
CAS 199594-74-6C20H15F2N3
2-(2-Chloro-3-pyridinyl)-1-(4-methoxybenzyl)-5,6-dimethyl-1H-1,3-benzimidazole chemical structure, C22H20ClN3O, CAS 861208-46-0
2-(2-Chloro-3-pyridinyl)-1-(4-methoxybenzyl)-5,6-dimethyl-1H-1,3-benzimidazole
CAS 861208-46-0C22H20ClN3O
2-(6-Chloro-3-pyridinyl)-1-(4-methoxybenzyl)-1H-1,3-benzimidazole chemical structure, C20H16ClN3O, CAS 337920-53-3
2-(6-Chloro-3-pyridinyl)-1-(4-methoxybenzyl)-1H-1,3-benzimidazole
CAS 337920-53-3C20H16ClN3O
2-(6-Chloro-3-pyridinyl)-1-[3-(trifluoromethyl)benzyl]-1H-1,3-benzimidazole chemical structure, C20H13ClF3N3, CAS 337920-54-4
2-(6-Chloro-3-pyridinyl)-1-[3-(trifluoromethyl)benzyl]-1H-1,3-benzimidazole
CAS 337920-54-4C20H13ClF3N3
1-Benzyl-2-(6-chloropyridin-3-yl)-5,6-dimethylbenzimidazole chemical structure, C21H18ClN3, CAS 337920-59-9
1-Benzyl-2-(6-chloropyridin-3-yl)-5,6-dimethylbenzimidazole
CAS 337920-59-9C21H18ClN3
2-(6-Chloro-3-pyridinyl)-1-(4-methoxybenzyl)-5,6-dimethyl-1H-1,3-benzimidazole chemical structure, C22H20ClN3O, CAS 337920-60-2
2-(6-Chloro-3-pyridinyl)-1-(4-methoxybenzyl)-5,6-dimethyl-1H-1,3-benzimidazole
CAS 337920-60-2C22H20ClN3O
2-(6-Chloro-3-pyridinyl)-5,6-dimethyl-1-(4-methylbenzyl)-1H-1,3-benzimidazole chemical structure, C22H20ClN3, CAS 337920-61-3
2-(6-Chloro-3-pyridinyl)-5,6-dimethyl-1-(4-methylbenzyl)-1H-1,3-benzimidazole
CAS 337920-61-3C22H20ClN3
1-Benzyl-2-(2-chloro-3-pyridinyl)-1H-1,3-benzimidazole chemical structure, C19H14ClN3, CAS 338411-19-1
1-Benzyl-2-(2-chloro-3-pyridinyl)-1H-1,3-benzimidazole
CAS 338411-19-1C19H14ClN3
2-(2-Chloropyridin-3-yl)-1-(3-methoxybenzyl)-1H-benzo[d]imidazole chemical structure, C20H16ClN3O, CAS 338411-22-6
2-(2-Chloropyridin-3-yl)-1-(3-methoxybenzyl)-1H-benzo[d]imidazole
CAS 338411-22-6C20H16ClN3O
2-(2-Chloro-3-pyridinyl)-1-(2-fluorobenzyl)-1H-1,3-benzimidazole chemical structure, C19H13ClFN3, CAS 338411-25-9
2-(2-Chloro-3-pyridinyl)-1-(2-fluorobenzyl)-1H-1,3-benzimidazole
CAS 338411-25-9C19H13ClFN3
2-(2-Chloro-3-pyridinyl)-1-(3-fluorobenzyl)-1H-1,3-benzimidazole chemical structure, C19H13ClFN3, CAS 338411-26-0
2-(2-Chloro-3-pyridinyl)-1-(3-fluorobenzyl)-1H-1,3-benzimidazole
CAS 338411-26-0C19H13ClFN3
2-(2-Chloro-3-pyridinyl)-1-(4-fluorobenzyl)-1H-1,3-benzimidazole chemical structure, C19H13ClFN3, CAS 338411-28-2
2-(2-Chloro-3-pyridinyl)-1-(4-fluorobenzyl)-1H-1,3-benzimidazole
CAS 338411-28-2C19H13ClFN3
1-(2-Chloro-6-fluorobenzyl)-2-(2-chloro-3-pyridinyl)-1H-1,3-benzimidazole chemical structure, C19H12Cl2FN3, CAS 338411-29-3
1-(2-Chloro-6-fluorobenzyl)-2-(2-chloro-3-pyridinyl)-1H-1,3-benzimidazole
CAS 338411-29-3C19H12Cl2FN3
1-(2-Chlorobenzyl)-2-(2-chloro-3-pyridinyl)-1H-1,3-benzimidazole chemical structure, C19H13Cl2N3, CAS 338411-31-7
1-(2-Chlorobenzyl)-2-(2-chloro-3-pyridinyl)-1H-1,3-benzimidazole
CAS 338411-31-7C19H13Cl2N3
1-(3-Chlorobenzyl)-2-(2-chloro-3-pyridinyl)-1H-1,3-benzimidazole chemical structure, C19H13Cl2N3, CAS 338411-32-8
1-(3-Chlorobenzyl)-2-(2-chloro-3-pyridinyl)-1H-1,3-benzimidazole
CAS 338411-32-8C19H13Cl2N3
1-(4-Chlorobenzyl)-2-(2-chloro-3-pyridinyl)-1H-1,3-benzimidazole chemical structure, C19H13Cl2N3, CAS 338411-33-9
1-(4-Chlorobenzyl)-2-(2-chloro-3-pyridinyl)-1H-1,3-benzimidazole
CAS 338411-33-9C19H13Cl2N3
2-(2-Chloro-3-pyridinyl)-1-(3-methylbenzyl)-1H-1,3-benzimidazole chemical structure, C20H16ClN3, CAS 338411-39-5
2-(2-Chloro-3-pyridinyl)-1-(3-methylbenzyl)-1H-1,3-benzimidazole
CAS 338411-39-5C20H16ClN3
2-(2-Chloro-3-pyridinyl)-1-(4-methylbenzyl)-1H-1,3-benzimidazole chemical structure, C20H16ClN3, CAS 338411-40-8
2-(2-Chloro-3-pyridinyl)-1-(4-methylbenzyl)-1H-1,3-benzimidazole
CAS 338411-40-8C20H16ClN3
2-(2-Chloro-3-pyridinyl)-1-(2-methylbenzyl)-1H-1,3-benzimidazole chemical structure, C20H16ClN3, CAS 338411-54-4
2-(2-Chloro-3-pyridinyl)-1-(2-methylbenzyl)-1H-1,3-benzimidazole
CAS 338411-54-4C20H16ClN3
2-(2-Chloro-3-pyridinyl)-1-(3-(trifluoromethyl)benzyl)-1H-1,3-benzimidazole chemical structure, C20H13ClF3N3, CAS 338411-55-5
2-(2-Chloro-3-pyridinyl)-1-(3-(trifluoromethyl)benzyl)-1H-1,3-benzimidazole
CAS 338411-55-5C20H13ClF3N3
2-(2-Chloro-3-pyridinyl)-1-(4-(trifluoromethyl)benzyl)-1H-1,3-benzimidazole chemical structure, C20H13ClF3N3, CAS 338411-56-6
2-(2-Chloro-3-pyridinyl)-1-(4-(trifluoromethyl)benzyl)-1H-1,3-benzimidazole
CAS 338411-56-6C20H13ClF3N3
2-(2-Chloro-3-pyridinyl)-5,6-dimethyl-1-(3-methylbenzyl)-1H-1,3-benzimidazole chemical structure, C22H20ClN3, CAS 344278-88-2
2-(2-Chloro-3-pyridinyl)-5,6-dimethyl-1-(3-methylbenzyl)-1H-1,3-benzimidazole
CAS 344278-88-2C22H20ClN3
2-(2-Chloro-3-pyridinyl)-1-(4-fluorobenzyl)-5,6-dimethyl-1H-1,3-benzimidazole chemical structure, C21H17ClFN3, CAS 344279-40-9
2-(2-Chloro-3-pyridinyl)-1-(4-fluorobenzyl)-5,6-dimethyl-1H-1,3-benzimidazole
CAS 344279-40-9C21H17ClFN3
2-(2-Chloro-3-pyridinyl)-5,6-dimethyl-1-(2-methylbenzyl)-1H-1,3-benzimidazole chemical structure, C22H20ClN3, CAS 344279-65-8
2-(2-Chloro-3-pyridinyl)-5,6-dimethyl-1-(2-methylbenzyl)-1H-1,3-benzimidazole
CAS 344279-65-8C22H20ClN3