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Murcko scaffold

Ring system with 4 rings and 23 atoms

43 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 23
Chemicals: 43
With full pages: 10

Scaffold SMILES

O=c1[nH]cccc1-c1nc2ccccc2n1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1[nH]cccc1-c1nc2ccccc2n1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

3-[5,6-Dichloro-1-(4-chlorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C19H12Cl3N3O, CAS 338774-07-5

3-[5,6-Dichloro-1-(4-chlorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 338774-07-5C₁₉H₁₂Cl₃N₃O

3-[5,6-Dichloro-1-(2-chlorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C19H12Cl3N3O, CAS 338774-08-6

3-[5,6-Dichloro-1-(2-chlorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 338774-08-6C₁₉H₁₂Cl₃N₃O

3-[5,6-Dichloro-1-(2-chloro-6-fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C19H11Cl3FN3O, CAS 338774-13-3

3-[5,6-Dichloro-1-(2-chloro-6-fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 338774-13-3C₁₉H₁₁Cl₃FN₃O

3-[5,6-Dichloro-1-(2-fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C19H12Cl2FN3O, CAS 338774-20-2

3-[5,6-Dichloro-1-(2-fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 338774-20-2C₁₉H₁₂Cl₂FN₃O

3-[5,6-Dichloro-1-(3-chlorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C19H12Cl3N3O, CAS 338774-22-4

3-[5,6-Dichloro-1-(3-chlorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 338774-22-4C₁₉H₁₂Cl₃N₃O

3-[5,6-Dichloro-1-(3-fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C19H12Cl2FN3O, CAS 338774-28-0

3-[5,6-Dichloro-1-(3-fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 338774-28-0C₁₉H₁₂Cl₂FN₃O

3-[5,6-Dichloro-1-(4-fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C19H12Cl2FN3O, CAS 338774-29-1

3-[5,6-Dichloro-1-(4-fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 338774-29-1C₁₉H₁₂Cl₂FN₃O

3-[5,6-Dichloro-1-(2-methylbenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C20H15Cl2N3O, CAS 338774-31-5

3-[5,6-Dichloro-1-(2-methylbenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 338774-31-5C₂₀H₁₅Cl₂N₃O

3-[1-(3-Chlorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C19H14ClN3O, CAS 860649-50-9

3-[1-(3-Chlorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 860649-50-9C₁₉H₁₄ClN₃O

3-[5,6-Dichloro-1-(4-methylbenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C20H15Cl2N3O, CAS 338412-00-3

3-[5,6-Dichloro-1-(4-methylbenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 338412-00-3C₂₀H₁₅Cl₂N₃O

3-[1-(4-Fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C19H14FN3O, CAS 861211-94-1

3-[1-(4-Fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 861211-94-1C₁₉H₁₄FN₃O

3-{1-[4-(tert-Butyl)benzyl]-1H-1,3-benzimidazol-2-yl}-2(1H)-pyridinone chemical structure, C23H23N3O, CAS 861211-95-2

3-{1-[4-(tert-Butyl)benzyl]-1H-1,3-benzimidazol-2-yl}-2(1H)-pyridinone

CAS 861211-95-2C₂₃H₂₃N₃O

3-[1-(3-Methylbenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C20H17N3O, CAS 861211-96-3

3-[1-(3-Methylbenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 861211-96-3C₂₀H₁₇N₃O

3-{5,6-Dichloro-1-[3-(trifluoromethyl)benzyl]-1H-1,3-benzimidazol-2-yl}-2(1H)-pyridinone chemical structure, C20H12Cl2F3N3O, CAS 338412-16-1

3-{5,6-Dichloro-1-[3-(trifluoromethyl)benzyl]-1H-1,3-benzimidazol-2-yl}-2(1H)-pyridinone

CAS 338412-16-1C₂₀H₁₂Cl₂F₃N₃O

3-[1-(2-Fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C19H14FN3O, CAS 861212-03-5

3-[1-(2-Fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 861212-03-5C₁₉H₁₄FN₃O

3-[1-(3-Fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C19H14FN3O, CAS 861212-04-6

3-[1-(3-Fluorobenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 861212-04-6C₁₉H₁₄FN₃O

3-[1-(4-Fluorobenzyl)-5,6-dimethyl-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C21H18FN3O, CAS 861212-05-7

3-[1-(4-Fluorobenzyl)-5,6-dimethyl-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 861212-05-7C₂₁H₁₈FN₃O

3-[1-(3-Methoxybenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C20H17N3O2, CAS 866136-22-3

3-[1-(3-Methoxybenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 866136-22-3C₂₀H₁₇N₃O₂

3-[1-(2-Chlorobenzyl)-5,6-dimethyl-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C21H18ClN3O, CAS 860787-63-9

3-[1-(2-Chlorobenzyl)-5,6-dimethyl-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 860787-63-9C₂₁H₁₈ClN₃O

3-[5,6-Dimethyl-1-(4-methylbenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C22H21N3O, CAS 860787-64-0

3-[5,6-Dimethyl-1-(4-methylbenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 860787-64-0C₂₂H₂₁N₃O

3-[5,6-Dimethyl-1-(2-methylbenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C22H21N3O, CAS 860787-66-2

3-[5,6-Dimethyl-1-(2-methylbenzyl)-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 860787-66-2C₂₂H₂₁N₃O

3-[1-(2,6-Dichlorobenzyl)-5,6-dimethyl-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C21H17Cl2N3O, CAS 860787-67-3

3-[1-(2,6-Dichlorobenzyl)-5,6-dimethyl-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 860787-67-3C₂₁H₁₇Cl₂N₃O

3-[1-(3-Fluorobenzyl)-5,6-dimethyl-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C21H18FN3O, CAS 860787-72-0

3-[1-(3-Fluorobenzyl)-5,6-dimethyl-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 860787-72-0C₂₁H₁₈FN₃O

3-[1-(2-Fluorobenzyl)-5,6-dimethyl-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone chemical structure, C21H18FN3O, CAS 860787-73-1

3-[1-(2-Fluorobenzyl)-5,6-dimethyl-1H-1,3-benzimidazol-2-yl]-2(1H)-pyridinone

CAS 860787-73-1C₂₁H₁₈FN₃O