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Murcko scaffold

5-(Pyrrolidin-2-yl)pyridin-2-ol scaffold

21 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
21
With full pages
4
Scaffold SMILES

O=c1ccc(C2CCCN2)c[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(Pyrrolidin-2-yl)pyridin-2-ol page
Murcko scaffold O=c1ccc(C2CCCN2)c[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

6-Hydroxynicotine chemical structure, C10H14N2O, CAS 3220-56-2
6-Hydroxynicotine
CAS 3220-56-2C10H14N2O
(S)-6-Hydroxynicotine chemical structure, C10H14N2O, CAS 10516-09-3
(S)-6-Hydroxynicotine
CAS 10516-09-3C10H14N2O
5-[(2R)-1-Methylpyrrolidin-2-yl]pyridin-2-ol chemical structure, C10H14N2O, CAS 22956-40-7
5-[(2R)-1-Methylpyrrolidin-2-yl]pyridin-2-ol
CAS 22956-40-7C10H14N2O
5-(Pyrrolidin-2-yl)pyridin-2-ol chemical structure, C9H12N2O, CAS 1270473-32-9
5-(Pyrrolidin-2-yl)pyridin-2-ol
CAS 1270473-32-9C9H12N2O
4-Methyl-5-(pyrrolidin-2-yl)pyridin-2-ol chemical structure, C10H14N2O, CAS 1270425-24-5
4-Methyl-5-(pyrrolidin-2-yl)pyridin-2-ol
CAS 1270425-24-5C10H14N2O
2-(6-Oxo-1,6-dihydropyridin-3-yl)pyrrolidine-1-carbaldehyde chemical structure, C10H12N2O2, CAS 1352494-04-2
2-(6-Oxo-1,6-dihydropyridin-3-yl)pyrrolidine-1-carbaldehyde
CAS 1352494-04-2C10H12N2O2
5-(1-Acetylpyrrolidin-2-yl)pyridin-2(1H)-one chemical structure, C11H14N2O2, CAS 1352514-92-1
5-(1-Acetylpyrrolidin-2-yl)pyridin-2(1H)-one
CAS 1352514-92-1C11H14N2O2
tert-Butyl 2-(6-hydroxypyridin-3-yl)pyrrolidine-1-carboxylate chemical structure, C14H20N2O3, CAS 1352511-81-9
tert-Butyl 2-(6-hydroxypyridin-3-yl)pyrrolidine-1-carboxylate
CAS 1352511-81-9C14H20N2O3
5-(1-Propylpyrrolidin-2-yl)pyridin-2(1H)-one chemical structure, C12H18N2O, CAS 1352521-75-5
5-(1-Propylpyrrolidin-2-yl)pyridin-2(1H)-one
CAS 1352521-75-5C12H18N2O
2-(6-Hydroxy-5-methylpyridin-3-yl)pyrrolidine-1-carbaldehyde chemical structure, C11H14N2O2, CAS 1352509-63-7
2-(6-Hydroxy-5-methylpyridin-3-yl)pyrrolidine-1-carbaldehyde
CAS 1352509-63-7C11H14N2O2
5-(1-Acetylpyrrolidin-2-yl)-3-methylpyridin-2(1H)-one chemical structure, C12H16N2O2, CAS 1352497-85-8
5-(1-Acetylpyrrolidin-2-yl)-3-methylpyridin-2(1H)-one
CAS 1352497-85-8C12H16N2O2
tert-Butyl 2-(6-hydroxy-5-methylpyridin-3-yl)pyrrolidine-1-carboxylate chemical structure, C15H22N2O3, CAS 1352509-69-3
tert-Butyl 2-(6-hydroxy-5-methylpyridin-3-yl)pyrrolidine-1-carboxylate
CAS 1352509-69-3C15H22N2O3
2-(6-Hydroxy-4-methylpyridin-3-yl)pyrrolidine-1-carbaldehyde chemical structure, C11H14N2O2, CAS 1352513-66-6
2-(6-Hydroxy-4-methylpyridin-3-yl)pyrrolidine-1-carbaldehyde
CAS 1352513-66-6C11H14N2O2
5-(1-Acetylpyrrolidin-2-yl)-4-methylpyridin-2(1H)-one chemical structure, C12H16N2O2, CAS 1352484-06-0
5-(1-Acetylpyrrolidin-2-yl)-4-methylpyridin-2(1H)-one
CAS 1352484-06-0C12H16N2O2
tert-Butyl 2-(6-hydroxy-4-methylpyridin-3-yl)pyrrolidine-1-carboxylate chemical structure, C15H22N2O3, CAS 1352521-07-3
tert-Butyl 2-(6-hydroxy-4-methylpyridin-3-yl)pyrrolidine-1-carboxylate
CAS 1352521-07-3C15H22N2O3
4-Methyl-5-(1-propylpyrrolidin-2-yl)pyridin-2-ol chemical structure, C13H20N2O, CAS 1352496-37-7
4-Methyl-5-(1-propylpyrrolidin-2-yl)pyridin-2-ol
CAS 1352496-37-7C13H20N2O
5-(1-Acetylpyrrolidin-2-yl)-6-methylpyridin-2(1H)-one chemical structure, C12H16N2O2, CAS 1352510-22-5
5-(1-Acetylpyrrolidin-2-yl)-6-methylpyridin-2(1H)-one
CAS 1352510-22-5C12H16N2O2
tert-Butyl 2-(6-hydroxy-2-methylpyridin-3-yl)pyrrolidine-1-carboxylate chemical structure, C15H22N2O3, CAS 1352501-80-4
tert-Butyl 2-(6-hydroxy-2-methylpyridin-3-yl)pyrrolidine-1-carboxylate
CAS 1352501-80-4C15H22N2O3
6-Methyl-5-(1-propyl-pyrrolidin-2-yl)-1H-pyridin-2-one chemical structure, C13H20N2O, CAS 1352504-18-7
6-Methyl-5-(1-propyl-pyrrolidin-2-yl)-1H-pyridin-2-one
CAS 1352504-18-7C13H20N2O
5-(Pyrrolidin-2-yl)pyridin-2-ol dihydrochloride chemical structure, C9H14Cl2N2O, CAS 2567496-10-8
5-(Pyrrolidin-2-yl)pyridin-2-ol dihydrochloride
CAS 2567496-10-8C9H14Cl2N2O
5-(1-Methylpyrrolidin-2-yl)pyridin-2-ol hydrochloride chemical structure, C10H15ClN2O, CAS 2694747-33-4
5-(1-Methylpyrrolidin-2-yl)pyridin-2-ol hydrochloride
CAS 2694747-33-4C10H15ClN2O