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Murcko scaffold

Ring system with 3 rings and 18 atoms

23 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
23
With full pages
16
Scaffold SMILES

O=c1ccnc2nc(SCc3ccccc3)[nH]n12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccnc2nc(SCc3ccccc3)[nH]n12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

2-(Benzylsulfanyl)-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C15H16N4OS, CAS 774561-85-2
2-(Benzylsulfanyl)-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 774561-85-2C15H16N4OS
2-Benzylthio-5-methyl-S-triazolo(1,5-A)pyrimidin-7-ol chemical structure, C13H12N4OS, CAS 51646-33-4
2-Benzylthio-5-methyl-S-triazolo(1,5-A)pyrimidin-7-ol
CAS 51646-33-4C13H12N4OS
2-Benzylsulfanyl-5-methoxymethyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one chemical structure, C14H14N4O2S, CAS 774561-87-4
2-Benzylsulfanyl-5-methoxymethyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
CAS 774561-87-4C14H14N4O2S
2-[(4-Chlorobenzyl)sulfanyl]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C13H11ClN4OS, CAS 898920-88-2
2-[(4-Chlorobenzyl)sulfanyl]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 898920-88-2C13H11ClN4OS
Ethyl 2-benzylsulfanyl-7-oxo-1H-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C15H14N4O3S, CAS 51646-43-6
Ethyl 2-benzylsulfanyl-7-oxo-1H-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
CAS 51646-43-6C15H14N4O3S
2-[(2-Chlorobenzyl)sulfanyl]-5-methyl-6-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C16H17ClN4OS, CAS 903466-72-8
2-[(2-Chlorobenzyl)sulfanyl]-5-methyl-6-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 903466-72-8C16H17ClN4OS
Methyl {2-[(2-chlorobenzyl)sulfanyl]-7-hydroxy[1,2,4]triazolo[1,5-a]pyrimidin-5-yl}acetate chemical structure, C15H13ClN4O3S, CAS 908499-03-6
Methyl {2-[(2-chlorobenzyl)sulfanyl]-7-hydroxy[1,2,4]triazolo[1,5-a]pyrimidin-5-yl}acetate
CAS 908499-03-6C15H13ClN4O3S
2-(Benzylthio)-5-methyl-6-(3-methylbutyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C18H22N4OS, CAS 896665-76-2
2-(Benzylthio)-5-methyl-6-(3-methylbutyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 896665-76-2C18H22N4OS
2-(Benzylthio)-5-isopropyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C15H16N4OS, CAS 896667-90-6
2-(Benzylthio)-5-isopropyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 896667-90-6C15H16N4OS
2-(Benzylsulfanyl)-5,6-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C14H14N4OS, CAS 898922-14-0
2-(Benzylsulfanyl)-5,6-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 898922-14-0C14H14N4OS
2-(Benzylsulfanyl)-6-ethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C15H16N4OS, CAS 898924-43-1
2-(Benzylsulfanyl)-6-ethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 898924-43-1C15H16N4OS
5-Methyl-2-[(4-methylbenzyl)thio][1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C14H14N4OS, CAS 899380-28-0
5-Methyl-2-[(4-methylbenzyl)thio][1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 899380-28-0C14H14N4OS
2-[[(2-Chlorophenyl)methyl]thio]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(1H)-one chemical structure, C13H11ClN4OS, CAS 898920-00-8
2-[[(2-Chlorophenyl)methyl]thio]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(1H)-one
CAS 898920-00-8C13H11ClN4OS
2-[(2-Chlorobenzyl)thio]-5-isopropyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C15H15ClN4OS, CAS 898924-57-7
2-[(2-Chlorobenzyl)thio]-5-isopropyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 898924-57-7C15H15ClN4OS
2-[(2-Chlorobenzyl)sulfanyl]-6-ethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C15H15ClN4OS, CAS 898918-86-0
2-[(2-Chlorobenzyl)sulfanyl]-6-ethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 898918-86-0C15H15ClN4OS
2-[(4-Chlorobenzyl)sulfanyl]-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C15H15ClN4OS, CAS 898915-91-8
2-[(4-Chlorobenzyl)sulfanyl]-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 898915-91-8C15H15ClN4OS
2-[(4-Methylbenzyl)thio]-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C16H18N4OS, CAS 899377-07-2
2-[(4-Methylbenzyl)thio]-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 899377-07-2C16H18N4OS
2-[(4-Chlorobenzyl)thio]-5-isopropyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C15H15ClN4OS, CAS 903436-23-7
2-[(4-Chlorobenzyl)thio]-5-isopropyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 903436-23-7C15H15ClN4OS
2-(((4-Chlorophenyl)methyl)thio)-5-methyl-6-propyl(1,2,4)triazolo(1,5-a)pyrimidin-7(1H)-one chemical structure, C16H17ClN4OS, CAS 903202-11-9
2-(((4-Chlorophenyl)methyl)thio)-5-methyl-6-propyl(1,2,4)triazolo(1,5-a)pyrimidin-7(1H)-one
CAS 903202-11-9C16H17ClN4OS
6-Butyl-2-[(4-chlorobenzyl)thio]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C17H19ClN4OS, CAS 898922-78-6
6-Butyl-2-[(4-chlorobenzyl)thio]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 898922-78-6C17H19ClN4OS
2-(Benzylsulfanyl)-6-(2-hydroxyethyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol chemical structure, C15H16N4O2S, CAS 898917-91-4
2-(Benzylsulfanyl)-6-(2-hydroxyethyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol
CAS 898917-91-4C15H16N4O2S
2-{[(2,5-Dichlorophenyl)methyl]sulfanyl}-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol chemical structure, C13H10Cl2N4OS, CAS 1383456-76-5
2-{[(2,5-Dichlorophenyl)methyl]sulfanyl}-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol
CAS 1383456-76-5C13H10Cl2N4OS
2-{[(2,5-Dichlorophenyl)methyl]sulfanyl}-5-Ethyl-[1,2,4]triazolo[1,5-A]pyrimidin-7-Ol chemical structure, C14H12Cl2N4OS, CAS 1383456-79-8
2-{[(2,5-Dichlorophenyl)methyl]sulfanyl}-5-Ethyl-[1,2,4]triazolo[1,5-A]pyrimidin-7-Ol
CAS 1383456-79-8C14H12Cl2N4OS