Murcko scaffold
Timoprazole scaffold
157 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 18
- Chemicals
- 157
- With full pages
- 54
Scaffold SMILES
O=S(Cc1ccccn1)c1nc2ccccc2[nH]1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=S(Cc1ccccn1)c1nc2ccccc2[nH]1](/scaffold/HBDKFZNDMVLSHM-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 157 chemicals
Lansoprazole
CAS 103577-45-3C16H14F3N3O2S
Omeprazole
CAS 73590-58-6C17H19N3O3S
Pantoprazole
CAS 102625-70-7C16H15F2N3O4S
Rabeprazole
CAS 117976-89-3C18H21N3O3S
Disuprazole
CAS 99499-40-8C16H17N3OS2
Picoprazole
CAS 78090-11-6C17H17N3O3S
Timoprazole
CAS 57237-97-5C13H11N3OS
Hydroxyomeprazole
CAS 92340-57-3C17H19N3O4S
SK&F 95448
CAS 97963-96-7C16H13F4N3O3S
4-Methoxy-6-(((6-methoxy-1H-benzimidazol-2-yl)sulfinyl)methyl)-5-methyl-3-pyridinecarboxylic acid
CAS 120003-72-7C17H17N3O5S
Omeprazole magnesium
CAS 95382-33-5C34H36MgN6O6S2
RefChem:116186
CAS 86604-68-4C16H14F3N3O2S
N-Methyl omeprazole
CAS 784143-42-6C18H21N3O3S
5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1-methyl-1H-benzimidazole
CAS 89352-76-1C18H21N3O3S
Esomeprazole magnesium
CAS 161973-10-0C34H36MgN6O6S2
Esomeprazole
CAS 119141-88-7C17H19N3O3S
Dexlansoprazole
CAS 138530-94-6C16H14F3N3O2S
Levolansoprazole
CAS 138530-95-7C16H14F3N3O2S
(R)-Omeprazole
CAS 119141-89-8C17H19N3O3S
Omeprazolemagnesium
C17H19MgN3O3S
5-Hydroxylansoprazole
CAS 131926-98-2C16H14F3N3O3S
Esomeprazole magnesium salt
CAS 1198768-91-0C17H19MgN3O3S
![1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1) chemical structure, C16H15F2N3NaO4S, CAS 138786-67-1](/s/WHCXDEORRDVLKS-UHFFFAOYSA-N.svg)
1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)
CAS 138786-67-1C16H15F2N3NaO4S
![5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole sodium salt chemical structure, C17H19N3NaO3S](/s/HVAJOLFRLWQQQL-UHFFFAOYSA-N.svg)
5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole sodium salt
C17H19N3NaO3S
- 1-Propanol, 3-[[2-[(1H-benzimidazol-2-ylsulfinyl)methyl]-3-methyl-4-pyridinyl]oxy]-117976-94-0C17H19N3O3S
- 5 suppliers(+)-Rabeprazole177795-60-7C18H21N3O3S
- 4-Desmethoxy-4-nitro Omeprazole317807-10-6C16H16N4O4S
- (-)-Pantoprazole142678-35-1C16H15F2N3O4S
- 2-[[(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole73590-60-0C16H17N3O2S
- 2-[[(4-Chloro-3-methoxy-2-pyridinyl)methyl]sulfinyl]-6-(difluoromethoxy)-1H-benzimidazole409098-86-8C15H12ClF2N3O3S
- 6-Chloro-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole73590-61-1C16H16ClN3O2S
- 5'-Desmethoxy-5'-methyl 7'-Methyl 3,5-Dimethyl Omeprazole73590-45-1C16H17N3O2S
- 5-o-Desmethylomeprazole151602-49-2C16H17N3O3S
- 6-Methoxy-2-[[(4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole124473-15-0C16H17N3O3S
- 2-[(4-Ethoxy-3-methyl-2-pyridinyl)-methylsulfinyl]-benzimidazole169905-00-4C16H17N3O2S
- 7 suppliersDexrabeprazole sodium171440-18-9C18H20N3NaO3S
- (S)-Rabeprazole177795-59-4C18H21N3O3S
- 40 suppliersOmeprazole sodium95510-70-6C17H18N3NaO3S
- 4 suppliersOmeprazole-N-oxide176219-04-8C17H19N3O4S
- Pantoprazole, (R)-142706-18-1C16H15F2N3O4S
- 2-(((4-Chloro-3-methyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole168167-42-8C14H12ClN3OS
- Pantoprazole impurity I812664-93-0C16H14ClF2N3O4S
- 4-Desmethoxypropoxyl-4-methoxy rabeprazole102804-77-3C15H15N3O2S
- Esomeprazole strontium anhydrous914613-86-8C34H36N6O6S2Sr
- 3 suppliersLansoprazole sodium226904-00-3C16H13F3N3NaO2S
- 2 suppliersOmeprazole (sodium)161796-77-6C17H18N3NaO3S
- 6-Ethyl-2-[(pyridin-2-yl)methanesulfinyl]-1H-benzimidazole60524-79-0C15H15N3OS
- 2-(((3-Methylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole60524-97-2C14H13N3OS
Related scaffolds
Same ring framework with different atoms or bond orders
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C(=Cc1nc2ccccc2[nH]1)c1ccccc149 chemicals![Scaffold c1ccc(OCc2nc3ccccc3[nH]2)cc1](/scaffold/XATKRQREMKIRLA-UHFFFAOYSA-N/structure.svg)
c1ccc(OCc2nc3ccccc3[nH]2)cc147 chemicals![Scaffold O=c1[nH]c(=O)c2nc(SCc3ccccc3)[nH]c2[nH]1](/scaffold/DPACPINNZAEEGT-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2nc(SCc3ccccc3)[nH]c2[nH]138 chemicals![Scaffold O=C(Nc1nc2ccccc2[nH]1)c1ccccc1](/scaffold/LYLQJTSHZYGWBO-UHFFFAOYSA-N/structure.svg)
O=C(Nc1nc2ccccc2[nH]1)c1ccccc137 chemicals![Scaffold c1ccc(CSc2nc3ccccc3[nH]2)cc1](/scaffold/IJINDUSMSVDESS-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2nc3ccccc3[nH]2)cc134 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]c(NCc3ccccc3)nc2[nH]1](/scaffold/GWEJMPIBANKNEQ-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]c(NCc3ccccc3)nc2[nH]132 chemicals
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c1ccc(CNc2nc3ccccc3[nH]2)cc128 chemicals
C(=Cc1ccccc1)C1=Nc2ccccc2C125 chemicals