Murcko scaffold
2-Benzylthiobenzimidazole scaffold
124 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 17
- Chemicals
- 124
- With full pages
- 34
Scaffold SMILES
c1ccc(CSc2nc3ccccc3[nH]2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold c1ccc(CSc2nc3ccccc3[nH]2)cc1](/scaffold/IJINDUSMSVDESS-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 124 chemicals
2-(((4-Chlorophenyl)methyl)thio)-1H-benzimidazole
CAS 23976-76-3C14H11ClN2S
2-(2,3,4,5,6-Pentafluoro-benzylsulfanyl)-1H-benzoimidazole
CAS 157609-68-2C14H7F5N2S
2-Benzylthiobenzimidazole
CAS 51290-77-8C14H12N2S
2-Benzylsulfanyl-6-methyl-1H-benzimidazole
CAS 206983-14-4C15H14N2S
![2-{[(4-Chlorophenyl)methyl]sulfanyl}-5-methyl-1H-1,3-benzodiazole chemical structure, C15H13ClN2S, CAS 333771-43-0](/s/PWJYBZWYQPNBKP-UHFFFAOYSA-N.svg)
2-{[(4-Chlorophenyl)methyl]sulfanyl}-5-methyl-1H-1,3-benzodiazole
CAS 333771-43-0C15H13ClN2S
![2-[(3-Chlorophenyl)methylsulfanyl]-6-methyl-1H-benzimidazole chemical structure, C15H13ClN2S, CAS 449813-22-3](/s/JVXBBULPPLINSU-UHFFFAOYSA-N.svg)
2-[(3-Chlorophenyl)methylsulfanyl]-6-methyl-1H-benzimidazole
CAS 449813-22-3C15H13ClN2S
![2-{[(2-Chlorophenyl)methyl]sulfanyl}-5-methyl-1H-1,3-benzodiazole chemical structure, C15H13ClN2S, CAS 312275-13-1](/s/YOLFMMYVRKEHJW-UHFFFAOYSA-N.svg)
2-{[(2-Chlorophenyl)methyl]sulfanyl}-5-methyl-1H-1,3-benzodiazole
CAS 312275-13-1C15H13ClN2S
![2-[(4-Fluorophenyl)methylsulfanyl]-6-methyl-1H-benzimidazole chemical structure, C15H13FN2S, CAS 342383-63-5](/s/HJDOWNODDJGPDO-UHFFFAOYSA-N.svg)
2-[(4-Fluorophenyl)methylsulfanyl]-6-methyl-1H-benzimidazole
CAS 342383-63-5C15H13FN2S
![2-{[(2-Fluorophenyl)methyl]sulfanyl}-5-methyl-1H-1,3-benzodiazole chemical structure, C15H13FN2S, CAS 449813-24-5](/s/OQFYSWXAAZSBOU-UHFFFAOYSA-N.svg)
2-{[(2-Fluorophenyl)methyl]sulfanyl}-5-methyl-1H-1,3-benzodiazole
CAS 449813-24-5C15H13FN2S
![5-Methyl-2-((4-methylbenzyl)thio)-1H-benzo[d]imidazole chemical structure, C16H16N2S, CAS 449813-26-7](/s/QKCJOAOPYIEEGM-UHFFFAOYSA-N.svg)
5-Methyl-2-((4-methylbenzyl)thio)-1H-benzo[d]imidazole
CAS 449813-26-7C16H16N2S
![5-Methyl-2-{[(3-methylphenyl)methyl]sulfanyl}-1H-1,3-benzodiazole chemical structure, C16H16N2S, CAS 449813-27-8](/s/UHRYKMHCMYVFES-UHFFFAOYSA-N.svg)
5-Methyl-2-{[(3-methylphenyl)methyl]sulfanyl}-1H-1,3-benzodiazole
CAS 449813-27-8C16H16N2S
![6-Methyl-2-[(4-nitrophenyl)methylthio]-1H-benzimidazole chemical structure, C15H13N3O2S, CAS 415722-19-9](/s/RUAWVULWPTYWLK-UHFFFAOYSA-N.svg)
6-Methyl-2-[(4-nitrophenyl)methylthio]-1H-benzimidazole
CAS 415722-19-9C15H13N3O2S
![6-Methyl-2-[(2-nitrophenyl)methylsulfanyl]-1H-benzimidazole chemical structure, C15H13N3O2S, CAS 449813-31-4](/s/LEHHHWRXEXIKDQ-UHFFFAOYSA-N.svg)
6-Methyl-2-[(2-nitrophenyl)methylsulfanyl]-1H-benzimidazole
CAS 449813-31-4C15H13N3O2S
2-Chlorobenzyl 1-ethyl-1H-benzimidazol-2-yl sulfide
CAS 340741-04-0C16H15ClN2S
Methyl 4-(1H-benzimidazol-2-ylsulfanylmethyl)benzoate
CAS 308298-17-1C16H14N2O2S
![2-[(3,4-Dichlorobenzyl)sulfanyl]-1H-benzimidazole chemical structure, C14H10Cl2N2S, CAS 353261-18-4](/s/VVYDXXBTEWTQJF-UHFFFAOYSA-N.svg)
2-[(3,4-Dichlorobenzyl)sulfanyl]-1H-benzimidazole
CAS 353261-18-4C14H10Cl2N2S
![2-{[(3-Methylphenyl)methyl]sulfanyl}-1H-1,3-benzodiazole chemical structure, C15H14N2S, CAS 253168-40-0](/s/NHKYIEMLFDDAPD-UHFFFAOYSA-N.svg)
2-{[(3-Methylphenyl)methyl]sulfanyl}-1H-1,3-benzodiazole
CAS 253168-40-0C15H14N2S
![2-{[(2-Chlorophenyl)methyl]sulfanyl}-1H-1,3-benzodiazole chemical structure, C14H11ClN2S, CAS 35838-26-7](/s/ZNOFJEVAANDKBD-UHFFFAOYSA-N.svg)
2-{[(2-Chlorophenyl)methyl]sulfanyl}-1H-1,3-benzodiazole
CAS 35838-26-7C14H11ClN2S
2-(2-Benzylsulfanylbenzimidazol-1-yl)ethanol
CAS 304444-47-1C16H16N2OS
![2-{[(4-Bromophenyl)methyl]sulfanyl}-1H-1,3-benzodiazole chemical structure, C14H11BrN2S, CAS 296273-25-1](/s/SSZXTFFESFXOKA-UHFFFAOYSA-N.svg)
2-{[(4-Bromophenyl)methyl]sulfanyl}-1H-1,3-benzodiazole
CAS 296273-25-1C14H11BrN2S
2-(4-Methoxy-benzylsulfanyl)-1H-benzoimidazole
CAS 321680-96-0C15H14N2OS
![2-[(4-Nitrobenzyl)thio]-1H-benzimidazole chemical structure, C14H11N3O2S, CAS 100541-50-2](/s/GQKNIBASRJXHPJ-UHFFFAOYSA-N.svg)
2-[(4-Nitrobenzyl)thio]-1H-benzimidazole
CAS 100541-50-2C14H11N3O2S
![2-[(4-Fluorophenyl)methylsulfanyl]-1H-benzimidazole chemical structure, C14H11FN2S, CAS 295361-62-5](/s/OMXRCMRPDVPIDR-UHFFFAOYSA-N.svg)
2-[(4-Fluorophenyl)methylsulfanyl]-1H-benzimidazole
CAS 295361-62-5C14H11FN2S
![6-Methoxy-2-[(4-methylphenyl)methylsulfanyl]-1H-benzimidazole chemical structure, C16H16N2OS, CAS 309735-05-5](/s/HRUYBRGMRSNLNW-UHFFFAOYSA-N.svg)
6-Methoxy-2-[(4-methylphenyl)methylsulfanyl]-1H-benzimidazole
CAS 309735-05-5C16H16N2OS
- Methyl 3-(1H-benzimidazol-2-ylsulfanylmethyl)benzoate298208-33-0C16H14N2O2S
- 1 suppliers2-{[(3-Nitrophenyl)methyl]sulfanyl}-1H-1,3-benzodiazole401589-66-0C14H11N3O2S
- 2-{[(4-Methylphenyl)methyl]sulfanyl}-1H-1,3-benzodiazole352333-42-7C15H14N2S
- 1H-Benzimidazol-2-yl 3-chlorobenzyl sulfide353261-16-2C14H11ClN2S
- 2-((2-Chloro-6-fluorobenzyl)thio)-1H-benzo[d]imidazole362005-14-9C14H10ClFN2S
- 2-[(2,4-Dichlorobenzyl)sulfanyl]-1H-benzimidazole313224-32-7C14H10Cl2N2S
- 2-(Benzylthio)-1-methyl-1H-benzo[d]imidazole26196-38-3C15H14N2S
- 2-[(2,6-Dichlorobenzyl)sulfanyl]-1H-benzimidazole353261-17-3C14H10Cl2N2S
- 2-[(4-Chlorophenyl)methylsulfanyl]-6-methoxy-1H-benzimidazole325822-30-8C15H13ClN2OS
- 2-[(3-Bromophenyl)methylsulfanyl]-1H-benzimidazole5571-61-9C14H11BrN2S
- 2-Benzylsulfanyl-5-methoxy-1-methylbenzimidazole327104-07-4C16H16N2OS
- 3-[2-(Benzylsulfanyl)-1H-benzimidazol-1-yl]propanoic acid313958-05-3C17H16N2O2S
- 2-[(2-Methoxyphenyl)methylsulfanyl]-1H-benzimidazole401577-93-3C15H14N2OS
- 5-Methoxy-2-((2-methoxybenzyl)thio)-1H-benzo[d]imidazole401595-06-0C16H16N2O2S
- 2-[(4-tert-Butylbenzyl)sulfanyl]-5-methoxy-1H-benzimidazole325823-05-0C19H22N2OS
- 2-(2,6-Difluoro-benzylsulfanyl)-1H-benzoimidazole333442-62-9C14H10F2N2S
- 2-[(4-Chlorophenyl)methylsulfanyl]-5-methoxy-1-methylbenzimidazole314051-83-7C16H15ClN2OS
- 2-((2-Chlorobenzyl)thio)-5-ethoxy-1H-benzo[d]imidazole433700-43-7C16H15ClN2OS
- 4-[(6-Bromo-1H-benzimidazol-2-yl)sulfanylmethyl]benzonitrile340739-52-8C15H10BrN3S
- [2-(Benzylthio)-1H-benzimidazol-1-yl]acetic acid313240-26-5C16H14N2O2S
- 2-[(4-tert-Butylphenyl)methylsulfanyl]-1H-benzimidazole296273-22-8C18H20N2S
- 2-Benzylsulfanyl-5-ethoxy-1-methylbenzimidazole303047-76-9C17H18N2OS
- 2-[(2,4-Dimethylbenzyl)thio]-1H-benzimidazole295361-85-2C16H16N2S
- 2-[(3-Fluoro-4-methoxyphenyl)methylsulfanyl]-1-methylbenzimidazole423734-72-9C16H15FN2OS
Related scaffolds
Same ring framework with different atoms or bond orders
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C(=Cc1nc2ccccc2[nH]1)c1ccccc149 chemicals![Scaffold c1ccc(OCc2nc3ccccc3[nH]2)cc1](/scaffold/XATKRQREMKIRLA-UHFFFAOYSA-N/structure.svg)
c1ccc(OCc2nc3ccccc3[nH]2)cc147 chemicals![Scaffold O=c1[nH]c(=O)c2nc(SCc3ccccc3)[nH]c2[nH]1](/scaffold/DPACPINNZAEEGT-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2nc(SCc3ccccc3)[nH]c2[nH]138 chemicals![Scaffold O=C(Nc1nc2ccccc2[nH]1)c1ccccc1](/scaffold/LYLQJTSHZYGWBO-UHFFFAOYSA-N/structure.svg)
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O=c1[nH]c(=O)c2[nH]c(NCc3ccccc3)nc2[nH]132 chemicals
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c1ccc(CNc2nc3ccccc3[nH]2)cc128 chemicals
C(=Cc1ccccc1)C1=Nc2ccccc2C125 chemicals