Murcko scaffold
2-(Phenoxymethyl)-1H-benzimidazole scaffold
201 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 17
- Chemicals
- 201
- With full pages
- 47
Scaffold SMILES
c1ccc(OCc2nc3ccccc3[nH]2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold c1ccc(OCc2nc3ccccc3[nH]2)cc1](/scaffold/XATKRQREMKIRLA-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 201 chemicals
2-((2,4-Dichlorophenoxy)methyl)-1H-benzimidazole
CAS 3156-21-6C14H10Cl2N2O
2-(Phenoxymethyl)-1H-benzimidazole
CAS 6637-29-2C14H12N2O
4-(1H-Benzimidazol-2-ylmethoxy)benzohydrazide
CAS 73418-54-9C15H14N4O2
Methyl 4-(1H-benzimidazol-2-ylmethoxy)benzoate
CAS 73418-50-5C16H14N2O3
2-(2-Chlorophenoxymethyl)-1H-1,3-benzodiazole
CAS 3384-30-3C14H11ClN2O
![2-[(4-Chlorophenoxy)methyl]-1H-1,3-benzodiazole chemical structure, C14H11ClN2O, CAS 3156-18-1](/s/ITCRYYSSWFKZJM-UHFFFAOYSA-N.svg)
2-[(4-Chlorophenoxy)methyl]-1H-1,3-benzodiazole
CAS 3156-18-1C14H11ClN2O
![2-[(4-Nitrophenoxy)methyl]-1H-benzimidazole chemical structure, C14H11N3O3, CAS 3156-22-7](/s/FLLWAOLNQOLQCD-UHFFFAOYSA-N.svg)
2-[(4-Nitrophenoxy)methyl]-1H-benzimidazole
CAS 3156-22-7C14H11N3O3
![2-[(4-Methoxyphenoxy)methyl]-1H-benzimidazole chemical structure, C15H14N2O2, CAS 120162-91-6](/s/FWFAQKXRSUWPCY-UHFFFAOYSA-N.svg)
2-[(4-Methoxyphenoxy)methyl]-1H-benzimidazole
CAS 120162-91-6C15H14N2O2
![1-Methyl-2-(phenoxymethyl)-1H-benzo[d]imidazole chemical structure, C15H14N2O, CAS 202065-29-0](/s/DOTIMNZXXZGBPP-UHFFFAOYSA-N.svg)
1-Methyl-2-(phenoxymethyl)-1H-benzo[d]imidazole
CAS 202065-29-0C15H14N2O
1-Methyl-2-o-tolyloxymethyl-1H-benzoimidazole
CAS 312748-38-2C16H16N2O
![2-[(2-Methoxyphenoxy)methyl]-1-methyl-1H-benzimidazole chemical structure, C16H16N2O2, CAS 298206-99-2](/s/JWVLAFDECSEOAL-UHFFFAOYSA-N.svg)
2-[(2-Methoxyphenoxy)methyl]-1-methyl-1H-benzimidazole
CAS 298206-99-2C16H16N2O2
![2-[(2-Bromophenoxy)methyl]-1H-benzimidazole chemical structure, C14H11BrN2O, CAS 3156-19-2](/s/DBILHVOKASGTBM-UHFFFAOYSA-N.svg)
2-[(2-Bromophenoxy)methyl]-1H-benzimidazole
CAS 3156-19-2C14H11BrN2O
1-Ethyl-2-(2-methoxy-phenoxymethyl)-1H-benzoimidazole
CAS 433700-04-0C17H18N2O2
![2-((4-Chlorophenoxy)methyl)-1-propyl-1H-benzo[d]imidazole chemical structure, C17H17ClN2O, CAS 370853-93-3](/s/XFDSMPXOUBPOGQ-UHFFFAOYSA-N.svg)
2-((4-Chlorophenoxy)methyl)-1-propyl-1H-benzo[d]imidazole
CAS 370853-93-3C17H17ClN2O
2-(Phenoxymethyl)-1-(propan-2-yl)-1H-1,3-benzodiazole
CAS 373611-05-3C17H18N2O
![2-((4-Chlorophenoxy)methyl)-1-isopropyl-1H-benzo[d]imidazole chemical structure, C17H17ClN2O, CAS 612049-71-5](/s/CPKDFBORUQCVRM-UHFFFAOYSA-N.svg)
2-((4-Chlorophenoxy)methyl)-1-isopropyl-1H-benzo[d]imidazole
CAS 612049-71-5C17H17ClN2O
![2-[(4-Methylphenoxy)methyl]-1H-benzimidazole chemical structure, C15H14N2O, CAS 3156-25-0](/s/NSQSYMQZJMZXRY-UHFFFAOYSA-N.svg)
2-[(4-Methylphenoxy)methyl]-1H-benzimidazole
CAS 3156-25-0C15H14N2O
![2-((4-(tert-Butyl)phenoxy)methyl)-1-propyl-1H-benzo[d]imidazole chemical structure, C21H26N2O, CAS 615280-67-6](/s/SXVCIVZYXNRAQE-UHFFFAOYSA-N.svg)
2-((4-(tert-Butyl)phenoxy)methyl)-1-propyl-1H-benzo[d]imidazole
CAS 615280-67-6C21H26N2O
![2-[(4-Methoxyphenoxy)methyl]-1-(3-methylbutyl)-1H-1,3-benzodiazole chemical structure, C20H24N2O2, CAS 443328-68-5](/s/ITBFXPOYUPWYOM-UHFFFAOYSA-N.svg)
2-[(4-Methoxyphenoxy)methyl]-1-(3-methylbutyl)-1H-1,3-benzodiazole
CAS 443328-68-5C20H24N2O2
![1-Allyl-2-[(2-isopropyl-5-methylphenoxy)methyl]-1H-benzimidazole chemical structure, C21H24N2O, CAS 385373-91-1](/s/WCCBEKJUZHVKSE-UHFFFAOYSA-N.svg)
1-Allyl-2-[(2-isopropyl-5-methylphenoxy)methyl]-1H-benzimidazole
CAS 385373-91-1C21H24N2O
![1-Isopentyl-2-((p-tolyloxy)methyl)-1H-benzo[d]imidazole chemical structure, C20H24N2O, CAS 443328-74-3](/s/QUDBGQAFVPPQKV-UHFFFAOYSA-N.svg)
1-Isopentyl-2-((p-tolyloxy)methyl)-1H-benzo[d]imidazole
CAS 443328-74-3C20H24N2O
![2-[(2-Methoxyphenoxy)methyl]-1-propyl-1H-1,3-benzodiazole chemical structure, C18H20N2O2, CAS 612049-72-6](/s/SZBHUEXHIXASTF-UHFFFAOYSA-N.svg)
2-[(2-Methoxyphenoxy)methyl]-1-propyl-1H-1,3-benzodiazole
CAS 612049-72-6C18H20N2O2
![2-[(2-Methoxyphenoxy)methyl]-1-(prop-2-en-1-yl)-1H-1,3-benzodiazole chemical structure, C18H18N2O2, CAS 433328-98-4](/s/RJZNJIIDNJHVER-UHFFFAOYSA-N.svg)
2-[(2-Methoxyphenoxy)methyl]-1-(prop-2-en-1-yl)-1H-1,3-benzodiazole
CAS 433328-98-4C18H18N2O2
1-(2,2-Diethoxyethyl)-2-(phenoxymethyl)benzimidazole
CAS 510723-47-4C20H24N2O3
- 2-[(2-Methylphenoxy)methyl]-1H-benzimidazole3156-23-8C15H14N2O
- 2-[(4-Chlorophenoxy)methyl]-1-methylbenzimidazole537009-34-0C15H13ClN2O
- 1-Propyl-2-((p-tolyloxy)methyl)-1H-benzo[d]imidazole433699-96-8C18H20N2O
- 1-(2-Methylpropyl)-2-(phenoxymethyl)benzimidazole378766-45-1C18H20N2O
- 2-{[5-Methyl-2-(propan-2-yl)phenoxy]methyl}-1-(2-methylpropyl)-1H-1,3-benzodiazole503431-04-7C22H28N2O
- 2-((2,4-Dichlorophenoxy)methyl)-1-isobutyl-1H-benzo[d]imidazole381201-07-6C18H18Cl2N2O
- 2-((2,4-Dichlorophenoxy)methyl)-1-propyl-1H-benzo[d]imidazole381682-50-4C17H16Cl2N2O
- 2-((4-Chlorophenoxy)methyl)-1-isobutyl-1H-benzo[d]imidazole433701-27-0C18H19ClN2O
- 1-Isobutyl-2-((p-tolyloxy)methyl)-1H-benzo[d]imidazole612049-65-7C19H22N2O
- 1-Allyl-2-((2,4-dichlorophenoxy)methyl)-1H-benzo[d]imidazole381198-69-2C17H14Cl2N2O
- 2-[(2,4-Dichlorophenoxy)methyl]-1-ethylbenzimidazole378211-95-1C16H14Cl2N2O
- 2-[(2,4-Dichlorophenoxy)methyl]-1-methyl-1H-1,3-benzodiazole202065-57-4C15H12Cl2N2O
- 2-(Phenoxymethyl)-1-prop-2-enylbenzimidazole381180-61-6C17H16N2O
- 2-((2,4-Dichlorophenoxy)methyl)-1-(2-methylallyl)-1H-benzo[d]imidazole477543-99-0C18H16Cl2N2O
- 1-Methyl-2-[(5-methyl-2-propan-2-ylphenoxy)methyl]benzimidazole379253-38-0C19H22N2O
- 1-Ethyl-2-[(5-methyl-2-propan-2-ylphenoxy)methyl]benzimidazole385373-89-7C20H24N2O
- 2-[(5-Methyl-2-propan-2-ylphenoxy)methyl]-1-(2-methylprop-2-enyl)benzimidazole385373-92-2C22H26N2O
- 2-((4-Methoxyphenoxy)methyl)-1-propyl-1H-benzo[d]imidazole379252-51-4C18H20N2O2
- 1-Isobutyl-2-(4-methoxy-phenoxymethyl)-1H-benzoimidazole428857-15-2C19H22N2O2
- 2-[(4-Methoxyphenoxy)methyl]-1-(prop-2-en-1-yl)-1H-1,3-benzodiazole380352-20-5C18H18N2O2
- 1-Ethyl-2-(4-methoxy-phenoxymethyl)-1H-benzoimidazole385373-85-3C17H18N2O2
- 2-[(4-Methoxyphenoxy)methyl]-1-methylbenzimidazole430444-53-4C16H16N2O2
- 1-(Methoxymethyl)-2-[(5-methyl-2-propan-2-ylphenoxy)methyl]benzimidazole385373-79-5C20H24N2O2
- 1-(2-Bromoallyl)-2-(phenoxymethyl)-1H-benzo[d]imidazole333746-93-3C17H15BrN2O
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1nc2ccccc2s1)c1ccccc1122 chemicals
O=C(Nc1ccccc1)c1cc2ccccc2o164 chemicals
O=C(Nc1cc2c(s1)CCCC2)c1ccccc160 chemicals![Scaffold O=S(Cc1ccccn1)c1nc2ccccc2[nH]1](/scaffold/HBDKFZNDMVLSHM-UHFFFAOYSA-N/structure.svg)
O=S(Cc1ccccn1)c1nc2ccccc2[nH]154 chemicals![Scaffold C(=Cc1nc2ccccc2[nH]1)c1ccccc1](/scaffold/QQLPPRIZUPEKMV-UHFFFAOYSA-N/structure.svg)
C(=Cc1nc2ccccc2[nH]1)c1ccccc149 chemicals![Scaffold O=c1[nH]c(=O)c2nc(SCc3ccccc3)[nH]c2[nH]1](/scaffold/DPACPINNZAEEGT-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2nc(SCc3ccccc3)[nH]c2[nH]138 chemicals![Scaffold O=C(Nc1nc2ccccc2[nH]1)c1ccccc1](/scaffold/LYLQJTSHZYGWBO-UHFFFAOYSA-N/structure.svg)
O=C(Nc1nc2ccccc2[nH]1)c1ccccc137 chemicals![Scaffold c1ccc(CSc2nc3ccccc3[nH]2)cc1](/scaffold/IJINDUSMSVDESS-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2nc3ccccc3[nH]2)cc134 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]c(NCc3ccccc3)nc2[nH]1](/scaffold/GWEJMPIBANKNEQ-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]c(NCc3ccccc3)nc2[nH]132 chemicals
O=C(Nc1ccccc1)c1cc2ccccc2s130 chemicals![Scaffold c1ccc(CNc2nc3ccccc3[nH]2)cc1](/scaffold/FXMPPQGQNSTUGE-UHFFFAOYSA-N/structure.svg)
c1ccc(CNc2nc3ccccc3[nH]2)cc128 chemicals
C(=Cc1ccccc1)C1=Nc2ccccc2C125 chemicals