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Murcko scaffold

4-Piperazin-1-yl-quinoline scaffold

392 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
392
With full pages
14
Scaffold SMILES

c1ccc2c(N3CCNCC3)ccnc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Piperazin-1-yl-quinoline page
Murcko scaffold c1ccc2c(N3CCNCC3)ccnc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 385 to 392 of 392 chemicals

N-(Propan-2-yl)-2-[4-(quinolin-4-yl)piperazin-1-yl]propanamide chemical structure, C19H26N4O, CAS 2741893-59-2
N-(Propan-2-yl)-2-[4-(quinolin-4-yl)piperazin-1-yl]propanamide
CAS 2741893-59-2C19H26N4O
N-tert-Butyl-4-(piperazin-1-yl)quinolin-2-amine chemical structure, C17H24N4, CAS 2556839-07-5
N-tert-Butyl-4-(piperazin-1-yl)quinolin-2-amine
CAS 2556839-07-5C17H24N4
2-[4-(6-Methoxyquinolin-4-yl)piperazin-1-yl]-N-(propan-2-yl)propanamide chemical structure, C20H28N4O2, CAS 2741889-82-5
2-[4-(6-Methoxyquinolin-4-yl)piperazin-1-yl]-N-(propan-2-yl)propanamide
CAS 2741889-82-5C20H28N4O2
1-{4-[7-(Trifluoromethyl)quinolin-4-yl]piperazin-1-yl}ethan-1-one chemical structure, C16H16F3N3O, CAS 2741928-21-0
1-{4-[7-(Trifluoromethyl)quinolin-4-yl]piperazin-1-yl}ethan-1-one
CAS 2741928-21-0C16H16F3N3O
N-Methyl-N-{2-oxo-2-[4-(quinolin-4-yl)piperazin-1-yl]ethyl}prop-2-enamide chemical structure, C19H22N4O2, CAS 2201937-53-1
N-Methyl-N-{2-oxo-2-[4-(quinolin-4-yl)piperazin-1-yl]ethyl}prop-2-enamide
CAS 2201937-53-1C19H22N4O2
tert-Butyl 4-(3-cyanoquinolin-4-yl)piperazine-1-carboxylate chemical structure, C19H22N4O2, CAS 2680661-83-8
tert-Butyl 4-(3-cyanoquinolin-4-yl)piperazine-1-carboxylate
CAS 2680661-83-8C19H22N4O2
6-Fluoro-4-(piperazin-1-yl)quinoline dihydrochloride chemical structure, C13H16Cl2FN3, CAS 2995276-77-0
6-Fluoro-4-(piperazin-1-yl)quinoline dihydrochloride
CAS 2995276-77-0C13H16Cl2FN3
tert-Butyl 4-(3-nitroquinolin-4-yl)piperazine-1-carboxylate chemical structure, C18H22N4O4, CAS 1026669-86-2
tert-Butyl 4-(3-nitroquinolin-4-yl)piperazine-1-carboxylate
CAS 1026669-86-2C18H22N4O4