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Murcko scaffold

4-Piperazin-1-yl-quinoline scaffold

392 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
392
With full pages
14
Scaffold SMILES

c1ccc2c(N3CCNCC3)ccnc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Piperazin-1-yl-quinoline page
Murcko scaffold c1ccc2c(N3CCNCC3)ccnc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 392 chemicals

Piperazine, 1-(7-chloro-4-quinolinyl)-4-(trichloroacetyl)- chemical structure, C15H13Cl4N3O, CAS 104667-94-9
Piperazine, 1-(7-chloro-4-quinolinyl)-4-(trichloroacetyl)-
CAS 104667-94-9C15H13Cl4N3O
Piperazine, 1-(chloroacetyl)-4-(7-chloro-4-quinolinyl)- chemical structure, C15H15Cl2N3O, CAS 104692-85-5
Piperazine, 1-(chloroacetyl)-4-(7-chloro-4-quinolinyl)-
CAS 104692-85-5C15H15Cl2N3O
7-Chloro-4-(4-nitrosopiperazin-1-yl)quinoline chemical structure, C13H13ClN4O, CAS 32863-63-1
7-Chloro-4-(4-nitrosopiperazin-1-yl)quinoline
CAS 32863-63-1C13H13ClN4O
Ethyl 6-chloro-8-methyl-4-(4-methylpiperazin-1-yl)quinoline-3-carboxylate chemical structure, C18H22ClN3O2, CAS 442150-38-1
Ethyl 6-chloro-8-methyl-4-(4-methylpiperazin-1-yl)quinoline-3-carboxylate
CAS 442150-38-1C18H22ClN3O2
2-Methyl-4-(piperazin-1-yl)quinoline chemical structure, C14H17N3, CAS 82241-22-3
2-Methyl-4-(piperazin-1-yl)quinoline
CAS 82241-22-3C14H17N3
7-Chloro-4-(piperazin-1-yl)quinoline chemical structure, C13H14ClN3, CAS 837-52-5
7-Chloro-4-(piperazin-1-yl)quinoline
CAS 837-52-5C13H14ClN3
7-Chloro-4-[4-(2-chloroethyl)-1-piperazinyl]quinoline chemical structure, C15H17Cl2N3, CAS 92645-66-4
7-Chloro-4-[4-(2-chloroethyl)-1-piperazinyl]quinoline
CAS 92645-66-4C15H17Cl2N3
2-Methyl-4-(4-methylpiperazin-1-yl)quinoline chemical structure, C15H19N3, CAS 503423-43-6
2-Methyl-4-(4-methylpiperazin-1-yl)quinoline
CAS 503423-43-6C15H19N3
4-Piperazin-1-yl-quinoline chemical structure, C13H15N3, CAS 118306-89-1
4-Piperazin-1-yl-quinoline
CAS 118306-89-1C13H15N3
4-[4-(2-Methylquinolin-4-yl)piperazin-1-yl]-4-oxobut-2-enoic acid chemical structure, C18H19N3O3, CAS 308088-20-2
4-[4-(2-Methylquinolin-4-yl)piperazin-1-yl]-4-oxobut-2-enoic acid
CAS 308088-20-2C18H19N3O3
1-[2,6-Bis(trifluoromethyl)quinol-4-yl]piperazine chemical structure, C15H13F6N3, CAS 401567-74-6
1-[2,6-Bis(trifluoromethyl)quinol-4-yl]piperazine
CAS 401567-74-6C15H13F6N3
1-[6-Bromo-2-(trifluoromethyl)quinol-4-yl]piperazine chemical structure, C14H13BrF3N3, CAS 541539-65-5
1-[6-Bromo-2-(trifluoromethyl)quinol-4-yl]piperazine
CAS 541539-65-5C14H13BrF3N3
1-[6-Chloro-2-(trifluoromethyl)quinol-4-yl]piperazine chemical structure, C14H13ClF3N3, CAS 401567-88-2
1-[6-Chloro-2-(trifluoromethyl)quinol-4-yl]piperazine
CAS 401567-88-2C14H13ClF3N3
8-Chloro-4-piperazin-1-yl-2-(trifluoromethyl)quinoline chemical structure, C14H13ClF3N3, CAS 401567-90-6
8-Chloro-4-piperazin-1-yl-2-(trifluoromethyl)quinoline
CAS 401567-90-6C14H13ClF3N3
1-[6-Fluoro-2-(trifluoromethyl)quinolin-4-yl]piperazine chemical structure, C14H13F4N3, CAS 541539-66-6
1-[6-Fluoro-2-(trifluoromethyl)quinolin-4-yl]piperazine
CAS 541539-66-6C14H13F4N3
8-Fluoro-4-piperazin-1-yl-2-(trifluoromethyl)quinoline chemical structure, C14H13F4N3, CAS 401567-86-0
8-Fluoro-4-piperazin-1-yl-2-(trifluoromethyl)quinoline
CAS 401567-86-0C14H13F4N3
6-Methyl-4-(piperazin-1-yl)-2-(trifluoromethyl)quinoline chemical structure, C15H16F3N3, CAS 544429-25-6
6-Methyl-4-(piperazin-1-yl)-2-(trifluoromethyl)quinoline
CAS 544429-25-6C15H16F3N3
4-(1-Piperazinyl)-2-(trifluoromethyl)quinoline chemical structure, C14H14F3N3, CAS 175203-79-9
4-(1-Piperazinyl)-2-(trifluoromethyl)quinoline
CAS 175203-79-9C14H14F3N3
7-Chloro-4-(4-methylsulfonylpiperazin-1-yl)quinoline chemical structure, C14H16ClN3O2S, CAS 775302-73-3
7-Chloro-4-(4-methylsulfonylpiperazin-1-yl)quinoline
CAS 775302-73-3C14H16ClN3O2S
4-(4-Methylpiperazin-1-yl)-8-nitroquinoline chemical structure, C14H16N4O2, CAS 709005-94-7
4-(4-Methylpiperazin-1-yl)-8-nitroquinoline
CAS 709005-94-7C14H16N4O2
1-[4-(2-Methylquinolin-4-yl)piperazin-1-yl]-3-prop-2-ynoxypropan-2-ol chemical structure, C20H25N3O2, CAS 4064-14-6
1-[4-(2-Methylquinolin-4-yl)piperazin-1-yl]-3-prop-2-ynoxypropan-2-ol
CAS 4064-14-6C20H25N3O2
2-Buten-1-one, 1-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]-, (2E)- chemical structure, C17H18ClN3O, CAS 1370264-19-9
2-Buten-1-one, 1-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]-, (2E)-
CAS 1370264-19-9C17H18ClN3O
7-Chloro-4-(4-methyl-1-piperazinyl)quinoline chemical structure, C14H16ClN3, CAS 84594-63-8
7-Chloro-4-(4-methyl-1-piperazinyl)quinoline
CAS 84594-63-8C14H16ClN3
Ethyl 4-(7-chloroquinolin-4-yl)piperazine-1-carboxylate chemical structure, C16H18ClN3O2, CAS 353257-16-6
Ethyl 4-(7-chloroquinolin-4-yl)piperazine-1-carboxylate
CAS 353257-16-6C16H18ClN3O2