Murcko scaffold
5H,6H,7H-Pyrrolo[3,4-b]pyridin-7-one scaffold
53 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 53
- With full pages
- 10
Scaffold SMILES
O=C1NCc2cccnc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 53 chemicals
![2,3-Dimethyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one chemical structure, C9H10N2O, CAS 90331-48-9](/s/FRZBXVJSHRJZBD-UHFFFAOYSA-N.svg)
2,3-Dimethyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one
CAS 90331-48-9C9H10N2O
![5-Hydroxy-5H-pyrrolo[3,4-b]pyridin-7(6H)-one chemical structure, C7H6N2O2, CAS 115012-10-7](/s/VZXZMFFSCIDRPJ-UHFFFAOYSA-N.svg)
5-Hydroxy-5H-pyrrolo[3,4-b]pyridin-7(6H)-one
CAS 115012-10-7C7H6N2O2
![5H,6H,7H-Pyrrolo[3,4-b]pyridin-7-one chemical structure, C7H6N2O, CAS 1211584-54-1](/s/CGULSYWKVCXEHE-UHFFFAOYSA-N.svg)
5H,6H,7H-Pyrrolo[3,4-b]pyridin-7-one
CAS 1211584-54-1C7H6N2O
![3-(7-Oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)propanoic acid chemical structure, C10H10N2O3, CAS 1206969-67-6](/s/LUUPKFFQILGAPH-UHFFFAOYSA-N.svg)
3-(7-Oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)propanoic acid
CAS 1206969-67-6C10H10N2O3
![2-(7-Oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)acetic acid chemical structure, C9H8N2O3, CAS 1206969-29-0](/s/KSHCVUGEBGIRCI-UHFFFAOYSA-N.svg)
2-(7-Oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)acetic acid
CAS 1206969-29-0C9H8N2O3
![3-Methyl-2-(7-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)butanoic acid chemical structure, C12H14N2O3, CAS 1218347-75-1](/s/IUVJQLCLTUQTTJ-UHFFFAOYSA-N.svg)
3-Methyl-2-(7-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)butanoic acid
CAS 1218347-75-1C12H14N2O3
2-Chloro-6-methyl-5H,6H,7H-pyrrolo(3,4-b)pyridin-7-one
CAS 1201924-35-7C8H7ClN2O
![3-Bromo-6-methyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one chemical structure, C8H7BrN2O, CAS 1254319-55-5](/s/BIAJIZVBOQVDTC-UHFFFAOYSA-N.svg)
3-Bromo-6-methyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one
CAS 1254319-55-5C8H7BrN2O
![3-Bromo-5H-pyrrolo[3,4-b]pyridin-7(6H)-one chemical structure, C7H5BrN2O, CAS 1346809-61-7](/s/MIVZJHZGDCIYBT-UHFFFAOYSA-N.svg)
3-Bromo-5H-pyrrolo[3,4-b]pyridin-7(6H)-one
CAS 1346809-61-7C7H5BrN2O
![4-Chloro-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one chemical structure, C7H5ClN2O, CAS 1402666-33-4](/s/HFMIDEZZRMURRV-UHFFFAOYSA-N.svg)
4-Chloro-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one
CAS 1402666-33-4C7H5ClN2O
![2-Chloro-5H-pyrrolo[3,4-b]pyridin-7(6H)-one chemical structure, C7H5ClN2O, CAS 1256786-85-2](/s/YWVRQJYBHYCBBF-UHFFFAOYSA-N.svg)
2-Chloro-5H-pyrrolo[3,4-b]pyridin-7(6H)-one
CAS 1256786-85-2C7H5ClN2O
![3-Methoxy-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one chemical structure, C8H8N2O2, CAS 1256791-04-4](/s/LSPYUNCDHBDWPA-UHFFFAOYSA-N.svg)
3-Methoxy-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one
CAS 1256791-04-4C8H8N2O2
![3-Methyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one chemical structure, C8H8N2O, CAS 1256806-40-2](/s/ASLKXJXKIZSDRW-UHFFFAOYSA-N.svg)
3-Methyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one
CAS 1256806-40-2C8H8N2O
![6-Ethyl-5H-pyrrolo[3,4-b]pyridin-7(6H)-one chemical structure, C9H10N2O, CAS 1046121-01-0](/s/TUNVGEXAGFCECO-UHFFFAOYSA-N.svg)
6-Ethyl-5H-pyrrolo[3,4-b]pyridin-7(6H)-one
CAS 1046121-01-0C9H10N2O
![7-Oxo-5H,6H,7H-pyrrolo[3,4-b]pyridine-2-carboxylic acid chemical structure, C8H6N2O3, CAS 1539911-77-7](/s/AJERUAYZGBWNDZ-UHFFFAOYSA-N.svg)
7-Oxo-5H,6H,7H-pyrrolo[3,4-b]pyridine-2-carboxylic acid
CAS 1539911-77-7C8H6N2O3
![Methyl 7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyridine-2-carboxylate chemical structure, C9H8N2O3, CAS 1518079-04-3](/s/BVSOHXCCUCXAMX-UHFFFAOYSA-N.svg)
Methyl 7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyridine-2-carboxylate
CAS 1518079-04-3C9H8N2O3
![3-Bromo-6-ethyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one chemical structure, C9H9BrN2O, CAS 1614234-03-5](/s/WPFPYNSAODHTCN-UHFFFAOYSA-N.svg)
3-Bromo-6-ethyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one
CAS 1614234-03-5C9H9BrN2O
![(6-Ethyl-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-3-yl)boronic acid chemical structure, C9H11BN2O3, CAS 1614234-04-6](/s/LCCLMACKSZYKJJ-UHFFFAOYSA-N.svg)
(6-Ethyl-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-3-yl)boronic acid
CAS 1614234-04-6C9H11BN2O3
4-Methyl-5H,6H,7H-pyrrolo(3,4-b)pyridin-7-one
CAS 2287340-98-9C8H8N2O
![3-Bromo-6-propan-2-yl-5H-pyrrolo[3,4-b]pyridin-7-one chemical structure, C10H11BrN2O, CAS 1352152-93-2](/s/HUJLEEBVVSLWMA-UHFFFAOYSA-N.svg)
3-Bromo-6-propan-2-yl-5H-pyrrolo[3,4-b]pyridin-7-one
CAS 1352152-93-2C10H11BrN2O
![5,6-Dihydro-6-propyl-7H-pyrrolo[3,4-b]pyridin-7-one chemical structure, C10H12N2O, CAS 1046121-02-1](/s/VOGPNQNYXJZNQU-UHFFFAOYSA-N.svg)
5,6-Dihydro-6-propyl-7H-pyrrolo[3,4-b]pyridin-7-one
CAS 1046121-02-1C10H12N2O
![2-Methyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one chemical structure, C8H8N2O, CAS 1784325-47-8](/s/SBFZCKJGCWRNMO-UHFFFAOYSA-N.svg)
2-Methyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one
CAS 1784325-47-8C8H8N2O
![Methyl 7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyridine-3-carboxylate chemical structure, C9H8N2O3, CAS 1822620-12-1](/s/NDZQERQVDIUZCU-UHFFFAOYSA-N.svg)
Methyl 7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyridine-3-carboxylate
CAS 1822620-12-1C9H8N2O3
![(7-Oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-3-yl)boronic acid chemical structure, C7H7BN2O3, CAS 1598437-67-2](/s/DIYAVMXLDMJTOX-UHFFFAOYSA-N.svg)
(7-Oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-3-yl)boronic acid
CAS 1598437-67-2C7H7BN2O3
- 2-Bromo-5,6-dihydropyrrolo[3,4-b]pyridin-7-one1823357-15-8C7H5BrN2O
- 4-Bromo-5,6-dihydro-7H-pyrrolo(3,4-b)pyridin-7-one1823870-64-9C7H5BrN2O
- 7-Oxo-5H,6H,7H-pyrrolo[3,4-b]pyridine-3-carboxylic acid2090355-24-9C8H6N2O3
- 3-Amino-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one hydrochloride2137936-74-2C7H8ClN3O
- 3-Amino-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one2055255-86-0C7H7N3O
- 3-(Ethenesulfonyl)-N-{7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-3-yl}propanamide2224315-17-5C12H13N3O4S
- 6-tert-Butyl-2-iodo-5H-pyrrolo[3,4-b]pyridin-7-one2376147-89-4C11H13IN2O
- 2-Iodo-6-methyl-5H-pyrrolo[3,4-b]pyridin-7-one2376147-84-9C8H7IN2O
- 2-Methoxy-4-methyl-6,7-dihydro-5H-pyrrolo[4,3-b]pyridin-7-one2170723-95-0C9H10N2O2
- Methyl 6,7-dihydro-4-methyl-7-oxo-5H-pyrrolo[3,4-b]pyridine-2-carboxylate2170723-78-9C10H10N2O3
- 2,4-Dimethyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one2170723-57-4C9H10N2O
- 4-Methoxy-6-methyl-5,6-dihydro-pyrrolo[3,4-b]pyridin-7-one2407051-39-0C9H10N2O2
- tert-Butyl (2R)-2-(2-chloro-7-oxo-5H-pyrrolo[3,4-b]pyridin-6-yl)propanoate2762930-20-9C14H17ClN2O3
- 4-Chloro-6-(propan-2-yl)-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one2138303-50-9C10H11ClN2O
- 4-Fluoro-6-methyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one2138303-58-7C8H7FN2O
- 4-Fluoro-6-propyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one2137798-35-5C10H11FN2O
- 4-Chloro-6-ethyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one2137636-99-6C9H9ClN2O
- 4-Chloro-6-propyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one2138150-02-2C10H11ClN2O
- 2-Chloro-N-{7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-3-yl}propanamide2411294-45-4C10H10ClN3O2
- 4-Chloro-6-methyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one2137732-24-0C8H7ClN2O
- 4-Fluoro-6-(propan-2-yl)-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one2138196-58-2C10H11FN2O
- Methyl 7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyridine-4-carboxylate2866308-03-2C9H8N2O3
- 6-Ethyl-4-fluoro-5H,6H,7H-pyrrolo[3,4-b]pyridin-7-one2137637-16-0C9H9FN2O
- Methyl 2-{4-chloro-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}acetate2763965-81-5C10H9ClN2O3
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