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Murcko scaffold

Ring system with 2 rings and 14 atoms

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
22
With full pages
11
Scaffold SMILES

O=c1[nH]cnnc1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cnnc1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

4-Amino-6-benzyl-3-methyl-1,2,4-triazin-5(4H)-one chemical structure, C11H12N4O, CAS 62191-16-6
4-Amino-6-benzyl-3-methyl-1,2,4-triazin-5(4H)-one
CAS 62191-16-6C11H12N4O
2-Amino-6-benzyl-3-(methylsulfanyl)-1,2,4-triazin-5(2H)-one chemical structure, C11H12N4OS, CAS 89569-67-5
2-Amino-6-benzyl-3-(methylsulfanyl)-1,2,4-triazin-5(2H)-one
CAS 89569-67-5C11H12N4OS
4-Amino-6-benzyl-3-(methylsulfanyl)-1,2,4-triazin-5(4H)-one chemical structure, C11H12N4OS, CAS 22285-41-2
4-Amino-6-benzyl-3-(methylsulfanyl)-1,2,4-triazin-5(4H)-one
CAS 22285-41-2C11H12N4OS
Ethyl 2-[5-hydroxy-6-benzyl-1,2,4-triazin-3-ylthio]acetate chemical structure, C14H15N3O3S, CAS 405920-65-2
Ethyl 2-[5-hydroxy-6-benzyl-1,2,4-triazin-3-ylthio]acetate
CAS 405920-65-2C14H15N3O3S
3-[(2E)-2-Butylidenehydrazinyl]-6-(3,4-dimethoxybenzyl)-1,2,4-triazin-5(2H)-one chemical structure, C16H21N5O3, CAS 374095-39-3
3-[(2E)-2-Butylidenehydrazinyl]-6-(3,4-dimethoxybenzyl)-1,2,4-triazin-5(2H)-one
CAS 374095-39-3C16H21N5O3
6-(4-Methoxybenzyl)-3-(methylthio)-1,2,4-triazin-5(4H)-one chemical structure, C12H13N3O2S, CAS 118740-03-7
6-(4-Methoxybenzyl)-3-(methylthio)-1,2,4-triazin-5(4H)-one
CAS 118740-03-7C12H13N3O2S
3-Amino-6-(3,4,5-trimethoxybenzyl)-1,2,4-triazin-5-ol chemical structure, C13H16N4O4, CAS 61404-59-9
3-Amino-6-(3,4,5-trimethoxybenzyl)-1,2,4-triazin-5-ol
CAS 61404-59-9C13H16N4O4
3-Hydrazinyl-6-(phenylmethyl)-1,2,4-triazin-5(2H)-one chemical structure, C10H11N5O, CAS 19542-08-6
3-Hydrazinyl-6-(phenylmethyl)-1,2,4-triazin-5(2H)-one
CAS 19542-08-6C10H11N5O
6-((3,4-Dimethoxyphenyl)methyl)-3-hydrazinyl-1,2,4-triazin-5(2H)-one chemical structure, C12H15N5O3, CAS 131468-54-7
6-((3,4-Dimethoxyphenyl)methyl)-3-hydrazinyl-1,2,4-triazin-5(2H)-one
CAS 131468-54-7C12H15N5O3
6-Benzyl-3-(methylsulfanyl)-1,2,4-triazin-5(2H)-one chemical structure, C11H11N3OS, CAS 7338-74-1
6-Benzyl-3-(methylsulfanyl)-1,2,4-triazin-5(2H)-one
CAS 7338-74-1C11H11N3OS
6-Benzyl-3-[(2E)-2-heptylidenehydrazinyl]-1,2,4-triazin-5(2H)-one chemical structure, C17H23N5O, CAS 311763-55-0
6-Benzyl-3-[(2E)-2-heptylidenehydrazinyl]-1,2,4-triazin-5(2H)-one
CAS 311763-55-0C17H23N5O
6-Benzyl-3-((2-hydroxyethyl)amino)-1,2,4-triazin-5(4H)-one chemical structure, C12H14N4O2, CAS 459218-66-7
6-Benzyl-3-((2-hydroxyethyl)amino)-1,2,4-triazin-5(4H)-one
CAS 459218-66-7C12H14N4O2
3-(Allylamino)-6-(4-methylbenzyl)-1,2,4-triazin-5(4H)-one chemical structure, C14H16N4O, CAS 899943-49-8
3-(Allylamino)-6-(4-methylbenzyl)-1,2,4-triazin-5(4H)-one
CAS 899943-49-8C14H16N4O
3-(Allylamino)-6-(4-methoxybenzyl)-1,2,4-triazin-5(4H)-one chemical structure, C14H16N4O2, CAS 905780-94-1
3-(Allylamino)-6-(4-methoxybenzyl)-1,2,4-triazin-5(4H)-one
CAS 905780-94-1C14H16N4O2
3-(Allylamino)-6-(4-isopropylbenzyl)-1,2,4-triazin-5(4H)-one chemical structure, C16H20N4O, CAS 899737-03-2
3-(Allylamino)-6-(4-isopropylbenzyl)-1,2,4-triazin-5(4H)-one
CAS 899737-03-2C16H20N4O
3-(Allylamino)-6-(4-ethoxybenzyl)-1,2,4-triazin-5(4H)-one chemical structure, C15H18N4O2, CAS 905765-08-4
3-(Allylamino)-6-(4-ethoxybenzyl)-1,2,4-triazin-5(4H)-one
CAS 905765-08-4C15H18N4O2
6-(4-Chlorobenzyl)-3-[(3-methoxypropyl)amino]-1,2,4-triazin-5-ol chemical structure, C14H17ClN4O2, CAS 895847-92-4
6-(4-Chlorobenzyl)-3-[(3-methoxypropyl)amino]-1,2,4-triazin-5-ol
CAS 895847-92-4C14H17ClN4O2
6-(4-Chlorobenzyl)-3-[(2-methoxyethyl)amino]-1,2,4-triazin-5-ol chemical structure, C13H15ClN4O2, CAS 898796-61-7
6-(4-Chlorobenzyl)-3-[(2-methoxyethyl)amino]-1,2,4-triazin-5-ol
CAS 898796-61-7C13H15ClN4O2
3-(Butylamino)-6-[(4-chlorophenyl)methyl]-2H-1,2,4-triazin-5-one chemical structure, C14H17ClN4O, CAS 895829-59-1
3-(Butylamino)-6-[(4-chlorophenyl)methyl]-2H-1,2,4-triazin-5-one
CAS 895829-59-1C14H17ClN4O
6-(3,4-Dimethoxybenzyl)-3-[(2-hydroxyethyl)amino]-1,2,4-triazin-5-ol chemical structure, C14H18N4O4, CAS 895827-78-8
6-(3,4-Dimethoxybenzyl)-3-[(2-hydroxyethyl)amino]-1,2,4-triazin-5-ol
CAS 895827-78-8C14H18N4O4
6-(4-Chlorobenzyl)-3-[(3-hydroxypropyl)amino]-1,2,4-triazin-5-ol chemical structure, C13H15ClN4O2, CAS 881432-79-7
6-(4-Chlorobenzyl)-3-[(3-hydroxypropyl)amino]-1,2,4-triazin-5-ol
CAS 881432-79-7C13H15ClN4O2
3-Amino-6-benzyl-1,2,4-triazin-5(4H)-one chemical structure, C10H10N4O, CAS 28544-78-7
3-Amino-6-benzyl-1,2,4-triazin-5(4H)-one
CAS 28544-78-7C10H10N4O