Murcko scaffold
Bicyclo[4.1.0]heptan-2-one scaffold
37 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 8
- Chemicals
- 37
- With full pages
- 6
Scaffold SMILES
O=C1CCCC2CC12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 37 of 37 chemicals
![Bicyclo[4.1.0]heptan-2-one chemical structure, C7H10O, CAS 5771-58-4](/s/CINFRRXNDRBHMD-UHFFFAOYSA-N.svg)
Bicyclo[4.1.0]heptan-2-one
CAS 5771-58-4C7H10O
Yttrium nitrate hexahydrate
CAS 13949-98-9C10H14O3
![1-Methylbicyclo[4.1.0]heptan-2-one chemical structure, C8H12O, CAS 14845-40-0](/s/ZSCULIADDRFIKK-UHFFFAOYSA-N.svg)
1-Methylbicyclo[4.1.0]heptan-2-one
CAS 14845-40-0C8H12O
![6-Methylbicyclo[4.1.0]heptan-2-one chemical structure, C8H12O, CAS 14845-41-1](/s/UEILJFFGJJRFFG-UHFFFAOYSA-N.svg)
6-Methylbicyclo[4.1.0]heptan-2-one
CAS 14845-41-1C8H12O
Carone
CAS 497-62-1C10H16O
![Bicyclo[4.1.0]heptan-2-one, 3,5,5-trimethyl- chemical structure, C10H16O, CAS 29750-24-1](/s/SKYRDOBZMWMBPY-UHFFFAOYSA-N.svg)
Bicyclo[4.1.0]heptan-2-one, 3,5,5-trimethyl-
CAS 29750-24-1C10H16O
![Bicyclo[4.1.0]heptan-2-one, 1,3-dimethyl- chemical structure, C9H14O, CAS 113282-70-5](/s/WSELLTNZXPRTLH-UHFFFAOYSA-N.svg)
Bicyclo[4.1.0]heptan-2-one, 1,3-dimethyl-
CAS 113282-70-5C9H14O
Ctk0I7585
CAS 24120-78-3C11H16O
![(1S,6R)-Bicyclo[4.1.0]heptan-2-one chemical structure, C7H10O, CAS 196488-91-2](/s/CINFRRXNDRBHMD-RITPCOANSA-N.svg)
(1S,6R)-Bicyclo[4.1.0]heptan-2-one
CAS 196488-91-2C7H10O
![(1r,6s)-Bicyclo[4.1.0]heptan-2-one chemical structure, C7H10O, CAS 82334-95-0](/s/CINFRRXNDRBHMD-NTSWFWBYSA-N.svg)
(1r,6s)-Bicyclo[4.1.0]heptan-2-one
CAS 82334-95-0C7H10O
![7,7-Dichlorobicyclo[4.1.0]heptan-2-one chemical structure, C7H8Cl2O, CAS 89215-50-9](/s/DUPNMSFQEBPXHS-UHFFFAOYSA-N.svg)
7,7-Dichlorobicyclo[4.1.0]heptan-2-one
CAS 89215-50-9C7H8Cl2O
![7,7-Dichloro-6-methylbicyclo[4.1.0]heptan-2-one chemical structure, C8H10Cl2O, CAS 89467-88-9](/s/NVBRXYMRBWYEFI-UHFFFAOYSA-N.svg)
7,7-Dichloro-6-methylbicyclo[4.1.0]heptan-2-one
CAS 89467-88-9C8H10Cl2O
![2-Oxobicyclo[4.1.0]heptane-1-acetic Acid Ethyl Ester chemical structure, C11H16O3, CAS 119137-76-7](/s/CONROKZEFXQQKS-UHFFFAOYSA-N.svg)
2-Oxobicyclo[4.1.0]heptane-1-acetic Acid Ethyl Ester
CAS 119137-76-7C11H16O3
![(1R,6S,7R)-7-Nitrobicyclo[4.1.0]heptan-2-one chemical structure, C7H9NO3, CAS 919530-29-3](/s/YELGNZJJCHLKFY-JSKYLQRQSA-N.svg)
(1R,6S,7R)-7-Nitrobicyclo[4.1.0]heptan-2-one
CAS 919530-29-3C7H9NO3
![5,5-Dimethylbicyclo[4.1.0]heptan-2-one chemical structure, C9H14O, CAS 88105-44-6](/s/ABUIFBOQTQEYLB-UHFFFAOYSA-N.svg)
5,5-Dimethylbicyclo[4.1.0]heptan-2-one
CAS 88105-44-6C9H14O
![1-Methyl-4-(1-methylethenyl)bicyclo[4.1.0]heptan-2-one chemical structure, C11H16O, CAS 2815-41-0](/s/DMFQYNMCGKIPKC-UHFFFAOYSA-N.svg)
1-Methyl-4-(1-methylethenyl)bicyclo[4.1.0]heptan-2-one
CAS 2815-41-0C11H16O
3,7,7-Trimethyl-3-(2-methyl-3-oxobutyl)bicyclo(4.1.0)heptan-2-one
CAS 85409-65-0C15H24O2
![7-(Trifluoromethyl)bicyclo[4.1.0]heptan-2-one chemical structure, C8H9F3O, CAS 1251922-94-7](/s/YHDOWHXDSBWDIT-UHFFFAOYSA-N.svg)
7-(Trifluoromethyl)bicyclo[4.1.0]heptan-2-one
CAS 1251922-94-7C8H9F3O
![7,7-Difluorobicyclo[4.1.0]heptan-2-one chemical structure, C7H8F2O, CAS 1251923-13-3](/s/ROGDHMVMJRRJEU-UHFFFAOYSA-N.svg)
7,7-Difluorobicyclo[4.1.0]heptan-2-one
CAS 1251923-13-3C7H8F2O
![Ethyl (1a,6a,7a)-2-oxo-bicyclo-[4.1.0]heptane-7-carboxylate chemical structure, C10H14O3, CAS 123880-22-8](/s/CZSYBCSTFANLEL-VDAHYXPESA-N.svg)
Ethyl (1a,6a,7a)-2-oxo-bicyclo-[4.1.0]heptane-7-carboxylate
CAS 123880-22-8C10H14O3
![(1S,6R,7S)-7-Nitrobicyclo[4.1.0]heptan-2-one chemical structure, C7H9NO3, CAS 919530-30-6](/s/YELGNZJJCHLKFY-QXRNQMCJSA-N.svg)
(1S,6R,7S)-7-Nitrobicyclo[4.1.0]heptan-2-one
CAS 919530-30-6C7H9NO3
![(1S,6R,7S)-2-Oxobicyclo[4.1.0]heptane-7-carboxylic acid chemical structure, C8H10O3, CAS 1932097-23-8](/s/FGQMQAVNCATITO-QXRNQMCJSA-N.svg)
(1S,6R,7S)-2-Oxobicyclo[4.1.0]heptane-7-carboxylic acid
CAS 1932097-23-8C8H10O3
![5-(Prop-2-yn-1-yl)bicyclo[4.1.0]heptan-2-one chemical structure, C10H12O, CAS 210172-12-6](/s/ZDXVGMHWRJLHPG-UHFFFAOYSA-N.svg)
5-(Prop-2-yn-1-yl)bicyclo[4.1.0]heptan-2-one
CAS 210172-12-6C10H12O
![6-(3-Buten-1-yl)-4,4-dimethylbicyclo[4.1.0]heptan-2-one chemical structure, C13H20O, CAS 137678-90-1](/s/NVIHKKWHFZMPME-UHFFFAOYSA-N.svg)
6-(3-Buten-1-yl)-4,4-dimethylbicyclo[4.1.0]heptan-2-one
CAS 137678-90-1C13H20O
- 3-(2,2-Difluoroacetyl)bicyclo[4.1.0]heptan-2-one1956335-29-7C9H10F2O2
- Rel-methyl (1R,6S,7R)-2-oxobicyclo[4.1.0]heptane-7-carboxylate134176-20-8C9H12O3
- (1R,4S,6S)-1-Methyl-4-(prop-1-en-2-yl)bicyclo[4.1.0]heptan-2-one33116-69-7C11H16O
- rac-(1R,6S,7R)-2-Oxobicyclo[4.1.0]heptane-7-carboxylic acid1903172-74-6C8H10O3
- 3-(Trifluoromethyl)bicyclo[4.1.0]heptan-2-one2247106-19-8C8H9F3O
- 1-{[(tert-Butyldimethylsilyl)oxy]methyl}bicyclo[4.1.0]heptan-2-one2613382-19-5C14H26O2Si
- rac-(1R,6R,7R)-7-Chloro-2-oxobicyclo[4.1.0]heptane-7-carboxylic acid2639378-05-3C8H9ClO3
- (1R,5S,6R)-5-tert-Butylbicyclo[4.1.0]heptan-2-one53715-68-7C11H18O
- 1-(Hydroxymethyl)bicyclo[4.1.0]heptan-2-one2764016-08-0C8H12O2
- Methyl rel-(1S,6S,7S)-7-ethyl-2-oxo-norcarane-1-carboxylate2760662-76-6C11H16O3
- Methyl rel-(1S,6S,7R)-7-ethyl-2-oxo-norcarane-1-carboxylate2760663-07-6C11H16O3
- Ethyl 6-methyl-2-oxo-norcarane-1-carboxylate2734197-42-1C11H16O3
- rac-(1R,6S,7S)-7-Nitrobicyclo[4.1.0]heptan-2-one2694058-51-8C7H9NO3
Related scaffolds
Same ring framework with different atoms or bond orders
