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Murcko scaffold

Ring system with 2 rings and 8 atoms

33 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
33
With full pages
11
Scaffold SMILES

O=C1C=CCC2OC12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CCC2OC12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

Epoxydon chemical structure, C7H8O4, CAS 24292-29-3
Epoxydon
CAS 24292-29-3C7H8O4
LL-C 10037alpha chemical structure, C8H9NO4, CAS 93752-54-6
LL-C 10037alpha
CAS 93752-54-6C8H9NO4
6-tert-Butyl-2,3-epoxy-1,4-benzoquinone chemical structure, C10H14O3, CAS 158592-93-9
6-tert-Butyl-2,3-epoxy-1,4-benzoquinone
CAS 158592-93-9C10H14O3
MM 14201 chemical structure, C6H7NO3, CAS 89020-30-4
MM 14201
CAS 89020-30-4C6H7NO3
7-Oxabicyclo(4.1.0)hept-3-en-2-one, 5-hydroxy-3-methyl-, (1R,5S,6R)- chemical structure, C7H8O3, CAS 67772-77-4
7-Oxabicyclo(4.1.0)hept-3-en-2-one, 5-hydroxy-3-methyl-, (1R,5S,6R)-
CAS 67772-77-4C7H8O3
Epoformin chemical structure, C7H8O3, CAS 52146-62-0
Epoformin
CAS 52146-62-0C7H8O3
(1S,2R,6S)-2-Hydroxy-4-(3-methylbut-3-en-1-ynyl)-7-oxabicyclo(4.1.0)hept-3-en-5-one chemical structure, C11H10O3, CAS 125555-67-1
(1S,2R,6S)-2-Hydroxy-4-(3-methylbut-3-en-1-ynyl)-7-oxabicyclo(4.1.0)hept-3-en-5-one
CAS 125555-67-1C11H10O3
7-Oxabicyclo[4.1.0]hept-3-en-2-one, 5-hydroxy-3-(hydroxymethyl)- chemical structure, C7H8O4, CAS 25163-24-0
7-Oxabicyclo[4.1.0]hept-3-en-2-one, 5-hydroxy-3-(hydroxymethyl)-
CAS 25163-24-0C7H8O4
(1R,5S,6R)-5-Hydroxy-6-(hydroxymethyl)-7-oxabicyclo[4.1.0]hept-3-en-2-one chemical structure, C7H8O4, CAS 55164-60-8
(1R,5S,6R)-5-Hydroxy-6-(hydroxymethyl)-7-oxabicyclo[4.1.0]hept-3-en-2-one
CAS 55164-60-8C7H8O4
Isoepoxydon chemical structure, C7H8O4, CAS 67772-76-3
Isoepoxydon
CAS 67772-76-3C7H8O4
Parasitenone chemical structure, C7H8O4, CAS 439906-13-5
Parasitenone
CAS 439906-13-5C7H8O4
2-Hydroxy-4-methoxy-7-oxabicyclo[4.1.0]hept-3-en-5-one chemical structure, C7H8O4, CAS 78472-10-3
2-Hydroxy-4-methoxy-7-oxabicyclo[4.1.0]hept-3-en-5-one
CAS 78472-10-3C7H8O4
5-[2-Hydroxy-5-oxo-4-[[(2E)-4,6,8-trimethylnona-2,7-dienoyl]amino]-7-oxabicyclo[4.1.0]hept-3-en-2-yl]pentanoic acid chemical structure, C23H33NO6, CAS 82516-67-4
5-[2-Hydroxy-5-oxo-4-[[(2E)-4,6,8-trimethylnona-2,7-dienoyl]amino]-7-oxabicyclo[4.1.0]hept-3-en-2-yl]pentanoic acid
CAS 82516-67-4C23H33NO6
(1R,5S,6R)-5-Hydroxy-4-(hydroxymethyl)-3-[(E)-prop-1-enyl]-7-oxabicyclo[4.1.0]hept-3-en-2-one chemical structure, C10H12O4, CAS 556795-50-7
(1R,5S,6R)-5-Hydroxy-4-(hydroxymethyl)-3-[(E)-prop-1-enyl]-7-oxabicyclo[4.1.0]hept-3-en-2-one
CAS 556795-50-7C10H12O4
Malyngamide H chemical structure, C26H41NO4, CAS 165337-92-8
Malyngamide H
CAS 165337-92-8C26H41NO4
Lachnumon chemical structure, C10H10Cl2O4, CAS 150671-02-6
Lachnumon
CAS 150671-02-6C10H10Cl2O4
Cetoniacytone B chemical structure, C7H9NO4, CAS 496775-49-6
Cetoniacytone B
CAS 496775-49-6C7H9NO4
Bromoxone chemical structure, C6H5BrO3, CAS 110786-63-5
Bromoxone
CAS 110786-63-5C6H5BrO3
N-((1R,2S,6R)-2-Hydroxy-6-(hydroxymethyl)-5-oxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)acetamide chemical structure, C9H11NO5, CAS 496775-48-5
N-((1R,2S,6R)-2-Hydroxy-6-(hydroxymethyl)-5-oxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)acetamide
CAS 496775-48-5C9H11NO5
Jesterone chemical structure, C15H20O4, CAS 349081-09-0
Jesterone
CAS 349081-09-0C15H20O4
Malyngamide N chemical structure, C26H40ClNO4, CAS 69121-75-1
Malyngamide N
CAS 69121-75-1C26H40ClNO4
Harveynone chemical structure, C11H10O3, CAS 142435-66-3
Harveynone
CAS 142435-66-3C11H10O3
Panepoxydone chemical structure, C11H14O4, CAS 31298-54-1
Panepoxydone
CAS 31298-54-1C11H14O4
Ambuic acid chemical structure, C19H26O6, CAS 340774-69-8
Ambuic acid
CAS 340774-69-8C19H26O6