CompoundList
Sign in
Murcko scaffold

2-Oxa-5-azabicyclo[4.1.0]heptane scaffold

76 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
7
Chemicals
76
With full pages
8
Scaffold SMILES

C1COC2CC2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Oxa-5-azabicyclo[4.1.0]heptane page
Murcko scaffold C1COC2CC2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 76 chemicals

(1R,4S,6S)-5-[(tert-Butoxy)carbonyl]-7-(trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid chemical structure, C12H16F3NO5, CAS 1955485-41-2
(1R,4S,6S)-5-[(tert-Butoxy)carbonyl]-7-(trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid
CAS 1955485-41-2C12H16F3NO5
(1S,4S,6R)-5-[(tert-Butoxy)carbonyl]-7-(trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid chemical structure, C12H16F3NO5, CAS 1955485-23-0
(1S,4S,6R)-5-[(tert-Butoxy)carbonyl]-7-(trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid
CAS 1955485-23-0C12H16F3NO5
(1R,4S,6S)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid hydrochloride chemical structure, C7H9ClF3NO3, CAS 1955485-19-4
(1R,4S,6S)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid hydrochloride
CAS 1955485-19-4C7H9ClF3NO3
(1R,4S,6S)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid chemical structure, C7H8F3NO3, CAS 1290672-17-1
(1R,4S,6S)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid
CAS 1290672-17-1C7H8F3NO3
(1S,4S,6R)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid hydrochloride chemical structure, C7H9ClF3NO3, CAS 1955485-39-8
(1S,4S,6R)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid hydrochloride
CAS 1955485-39-8C7H9ClF3NO3
(1S,4S,6R)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid chemical structure, C7H8F3NO3, CAS 1290672-18-2
(1S,4S,6R)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid
CAS 1290672-18-2C7H8F3NO3
7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane hydrochloride chemical structure, C6H9ClF3NO, CAS 1235439-60-7
7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane hydrochloride
CAS 1235439-60-7C6H9ClF3NO
7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane chemical structure, C6H8F3NO, CAS 1235528-17-2
7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane
CAS 1235528-17-2C6H8F3NO
2-Oxa-5-azabicyclo[4.1.0]heptane chemical structure, C5H9NO, CAS 166756-12-3
2-Oxa-5-azabicyclo[4.1.0]heptane
CAS 166756-12-3C5H9NO
(1S,4S,6R)-5-[(tert-Butoxy)carbonyl]-7,7-difluoro-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid chemical structure, C11H15F2NO5, CAS 1955473-86-5
(1S,4S,6R)-5-[(tert-Butoxy)carbonyl]-7,7-difluoro-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid
CAS 1955473-86-5C11H15F2NO5
(1R,6S,7S)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane chemical structure, C6H8F3NO, CAS 1486468-43-2
(1R,6S,7S)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane
CAS 1486468-43-2C6H8F3NO
7,7-Difluoro-2-oxa-5-azabicyclo[4.1.0]heptane chemical structure, C5H7F2NO, CAS 1258640-26-4
7,7-Difluoro-2-oxa-5-azabicyclo[4.1.0]heptane
CAS 1258640-26-4C5H7F2NO
rac-(1R,6S,7R)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane chemical structure, C6H8F3NO, CAS 1932618-95-5
rac-(1R,6S,7R)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane
CAS 1932618-95-5C6H8F3NO
(1R,6S)-2-Oxa-5-azabicyclo[4.1.0]heptane chemical structure, C5H9NO, CAS 2351211-01-1
(1R,6S)-2-Oxa-5-azabicyclo[4.1.0]heptane
CAS 2351211-01-1C5H9NO
(1S,6R)-2-Oxa-5-azabicyclo[4.1.0]heptane chemical structure, C5H9NO, CAS 2351211-00-0
(1S,6R)-2-Oxa-5-azabicyclo[4.1.0]heptane
CAS 2351211-00-0C5H9NO
2-Oxa-5-azabicyclo[4.1.0]heptane hydrochloride chemical structure, C5H10ClNO, CAS 1354952-28-5
2-Oxa-5-azabicyclo[4.1.0]heptane hydrochloride
CAS 1354952-28-5C5H10ClNO
5-[(tert-Butoxy)carbonyl]-7-(trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid chemical structure, C12H16F3NO5, CAS 1822540-63-5
5-[(tert-Butoxy)carbonyl]-7-(trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid
CAS 1822540-63-5C12H16F3NO5
7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid hydrochloride chemical structure, C7H9ClF3NO3, CAS 1822443-98-0
7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid hydrochloride
CAS 1822443-98-0C7H9ClF3NO3
7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid chemical structure, C7H8F3NO3, CAS 1933720-17-2
7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid
CAS 1933720-17-2C7H8F3NO3
5-((tert-Butoxy)carbonyl)-7,7-difluoro-2-oxa-5-azabicyclo(4.1.0)heptane-4-carboxylic acid chemical structure, C11H15F2NO5, CAS 1822535-60-3
5-((tert-Butoxy)carbonyl)-7,7-difluoro-2-oxa-5-azabicyclo(4.1.0)heptane-4-carboxylic acid
CAS 1822535-60-3C11H15F2NO5
tert-Butyl 7,7-difluoro-2-oxa-5-azabicyclo[4.1.0]heptane-5-carboxylate chemical structure, C10H15F2NO3, CAS 1461706-61-5
tert-Butyl 7,7-difluoro-2-oxa-5-azabicyclo[4.1.0]heptane-5-carboxylate
CAS 1461706-61-5C10H15F2NO3
5-[(tert-Butoxy)carbonyl]-2-oxa-5-azabicyclo[4.1.0]heptane-7-carboxylic acid chemical structure, C11H17NO5, CAS 1992978-79-6
5-[(tert-Butoxy)carbonyl]-2-oxa-5-azabicyclo[4.1.0]heptane-7-carboxylic acid
CAS 1992978-79-6C11H17NO5
rac-(1R,6S,7S)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane chemical structure, C6H8F3NO, CAS 1305712-30-4
rac-(1R,6S,7S)-7-(Trifluoromethyl)-2-oxa-5-azabicyclo[4.1.0]heptane
CAS 1305712-30-4C6H8F3NO
tert-Butyl 2-oxa-5-azabicyclo[4.1.0]heptane-5-carboxylate chemical structure, C10H17NO3, CAS 2421735-39-7
tert-Butyl 2-oxa-5-azabicyclo[4.1.0]heptane-5-carboxylate
CAS 2421735-39-7C10H17NO3