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Murcko scaffold

Ring system with 2 rings and 9 atoms

31 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 9
Chemicals: 31
With full pages: 3

Scaffold SMILES

O=C1OCC2OCOC12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1OCC2OCOC12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

(3aS,6R,6aS)-6-(Hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-4-one chemical structure, C8H12O5, CAS 56543-10-3

(3aS,6R,6aS)-6-(Hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-4-one

CAS 56543-10-3C₈H₁₂O₅

2,3-O-Isopropylidene-D-erythronolactone chemical structure, C7H10O4, CAS 51607-16-0

2,3-O-Isopropylidene-D-erythronolactone

CAS 51607-16-0C₇H₁₀O₄

2,2-Dimethyldihydrofuro(3,4-d)(1,3)dioxol-4(3aH)-one chemical structure, C7H10O4, CAS 25581-41-3

2,2-Dimethyldihydrofuro(3,4-d)(1,3)dioxol-4(3aH)-one

CAS 25581-41-3C₇H₁₀O₄

6-Hydroxymethyl-2,2-dimethyl-dihydro-furo(3,4-d)(1,3)dioxol-4-one chemical structure, C8H12O5, CAS 30725-00-9

6-Hydroxymethyl-2,2-dimethyl-dihydro-furo(3,4-d)(1,3)dioxol-4-one

CAS 30725-00-9C₈H₁₂O₅

AC1Lbqxa chemical structure, C8H11BrO4, CAS 94324-23-9

CAS 94324-23-9C₈H₁₁BrO₄

(3aS,6aS)-2,2-Dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one chemical structure, C7H10O4, CAS 37669-02-6

(3aS,6aS)-2,2-Dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one

CAS 37669-02-6C₇H₁₀O₄

6-[[tert-Butyl(dimethyl)silyl]oxymethyl]-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-4-one chemical structure, C14H26O5Si, CAS 1044813-00-4

6-[[tert-Butyl(dimethyl)silyl]oxymethyl]-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-4-one

CAS 1044813-00-4C₁₄H₂₆O₅Si

(3AS,6S,6AS)-6-(Hydroxymethyl)-2,2-dimethyldihydrofuro[3,4-D][1,3]dioxol-4(3AH)-one chemical structure, C8H12O5, CAS 83085-15-8

(3AS,6S,6AS)-6-(Hydroxymethyl)-2,2-dimethyldihydrofuro[3,4-D][1,3]dioxol-4(3AH)-one

CAS 83085-15-8C₈H₁₂O₅

2,3-O-Isopropylidene-L-lyxono-1,4-lactone chemical structure, C8H12O5, CAS 152006-17-2

2,3-O-Isopropylidene-L-lyxono-1,4-lactone

CAS 152006-17-2C₈H₁₂O₅

((3AR,4R,6aR)-2,2-dimethyl-6-oxotetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl acetate chemical structure, C10H14O6, CAS 32257-17-3

((3AR,4R,6aR)-2,2-dimethyl-6-oxotetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl acetate

CAS 32257-17-3C₁₀H₁₄O₆

(3aR,6R,6aR)-6-(((tert-Butyldimethylsilyl)oxy)methyl)-2,2-dimethyl-tetrahydro-2H-furo(3,4-d)(1,3)dioxol-4-one chemical structure, C14H26O5Si, CAS 75467-36-6

(3aR,6R,6aR)-6-(((tert-Butyldimethylsilyl)oxy)methyl)-2,2-dimethyl-tetrahydro-2H-furo(3,4-d)(1,3)dioxol-4-one

CAS 75467-36-6C₁₄H₂₆O₅Si

2-C-Methyl-2,3-O-isopropylidene-D-ribono-1,4-lactone chemical structure, C9H14O5, CAS 23709-41-3

2-C-Methyl-2,3-O-isopropylidene-D-ribono-1,4-lactone

CAS 23709-41-3C₉H₁₄O₅

(3aR,6R,6aR)-6-(Hydroxymethyl)-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-4-one chemical structure, C6H8O5, CAS 279682-97-2

(3aR,6R,6aR)-6-(Hydroxymethyl)-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-4-one

CAS 279682-97-2C₆H₈O₅

[(3aR,6R,6aR)-2,2-Dimethyl-4-oxo-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-6-yl]methyl methanesulfonate chemical structure, C9H14O7S, CAS 89747-54-6

[(3aR,6R,6aR)-2,2-Dimethyl-4-oxo-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-6-yl]methyl methanesulfonate

CAS 89747-54-6C₉H₁₄O₇S

2,3-O-Isopropylidene-L-gulonolactone chemical structure, C9H14O6, CAS 94840-08-1

2,3-O-Isopropylidene-L-gulonolactone

CAS 94840-08-1C₉H₁₄O₆

(3AS,6R,6aS)-6-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one chemical structure, C14H26O5Si, CAS 1266546-70-6

(3AS,6R,6aS)-6-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one

CAS 1266546-70-6C₁₄H₂₆O₅Si

5-Bromo-5-deoxy-2-C-methyl-2,3-o-(1-methylethylidene)-D-ribonic-gamma-lactone chemical structure, C9H13BrO4, CAS 157666-07-4

5-Bromo-5-deoxy-2-C-methyl-2,3-o-(1-methylethylidene)-D-ribonic-gamma-lactone

CAS 157666-07-4C₉H₁₃BrO₄

5-Azido-6-(tert-butyldimethylsilyl)-2,3-O-isopropylidene L-Gulono-1,4-lactone chemical structure, C15H27N3O5Si, CAS 118464-49-6

5-Azido-6-(tert-butyldimethylsilyl)-2,3-O-isopropylidene L-Gulono-1,4-lactone

CAS 118464-49-6C₁₅H₂₇N₃O₅Si

Dihydro-6-methoxy-2,2-dimethylfuro(3,4-d)-1,3-dioxol-4(3aH)-one chemical structure, C8H12O5, CAS 127758-34-3

Dihydro-6-methoxy-2,2-dimethylfuro(3,4-d)-1,3-dioxol-4(3aH)-one

CAS 127758-34-3C₈H₁₂O₅

(3aS,6R,6aR)-Dihydro-6-methoxy-2,2-dimethylfuro[3,4-d]-1,3-dioxol-4(3aH)-one chemical structure, C8H12O5, CAS 125851-01-6

(3aS,6R,6aR)-Dihydro-6-methoxy-2,2-dimethylfuro[3,4-d]-1,3-dioxol-4(3aH)-one

CAS 125851-01-6C₈H₁₂O₅

(3aR,6aR)-Dihydro-2,2,3a-trimethylfuro[3,4-d]-1,3-dioxol-4(3aH)-one chemical structure, C8H12O4, CAS 18465-72-0

(3aR,6aR)-Dihydro-2,2,3a-trimethylfuro[3,4-d]-1,3-dioxol-4(3aH)-one

CAS 18465-72-0C₈H₁₂O₄

5-Azido-5-deoxy-2,3-O-isopropylidene-D-lyxono-1,4-lactone chemical structure, C8H11N3O4, CAS 122194-04-1

5-Azido-5-deoxy-2,3-O-isopropylidene-D-lyxono-1,4-lactone

CAS 122194-04-1C₈H₁₁N₃O₄

(3aR,6R,6aR)-6-(2-Methoxypropan-2-yloxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-4-one chemical structure, C12H20O6, CAS 162635-53-2

(3aR,6R,6aR)-6-(2-Methoxypropan-2-yloxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-4-one

CAS 162635-53-2C₁₂H₂₀O₆

D-Erythruronolactone acetonide chemical structure, C7H10O5, CAS 85254-46-2

D-Erythruronolactone acetonide

CAS 85254-46-2C₇H₁₀O₅