Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 5 rings and 30 atoms

40 chemicals on CompoundList share this ring system.

Rings: 5
Scaffold atoms: 30
Chemicals: 40
With full pages: 9

Scaffold SMILES

c1ccc(COc2ccc(Nc3ncnc4ccc(-c5ccco5)cc34)cc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(COc2ccc(Nc3ncnc4ccc(-c5ccco5)cc34)cc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

Lapatinib chemical structure, C29H26ClFN4O4S, CAS 231277-92-2

CAS 231277-92-2C₂₉H₂₆ClFN₄O₄S

Lapatinib impurity 46 chemical structure, C31H30ClFN4O4S, CAS 320337-10-8

Lapatinib impurity 46

CAS 320337-10-8C₃₁H₃₀ClFN₄O₄S

N-(4-(Benzyloxy)phenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)furan-2-yl)quinazolin-4-amine chemical structure, C29H28N4O4S, CAS 231278-05-0

N-(4-(Benzyloxy)phenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)furan-2-yl)quinazolin-4-amine

CAS 231278-05-0C₂₉H₂₈N₄O₄S

Desfluoro lapatinib chemical structure, C29H27ClN4O4S, CAS 231277-91-1

Desfluoro lapatinib

CAS 231277-91-1C₂₉H₂₇ClN₄O₄S

Sdccggsk-0000340.P001 chemical structure, C29H28N4O4S, CAS 231277-83-1

Sdccggsk-0000340.P001

CAS 231277-83-1C₂₉H₂₈N₄O₄S

Deschloro lapatinib chemical structure, C29H27FN4O4S, CAS 633370-23-7

Deschloro lapatinib

CAS 633370-23-7C₂₉H₂₇FN₄O₄S

Lapatinib ditosylate anhydrous chemical structure, C43H42ClFN4O10S3, CAS 388082-77-7

Lapatinib ditosylate anhydrous

CAS 388082-77-7C₄₃H₄₂ClFN₄O₁₀S₃

N-[3-Bromo-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine chemical structure, C29H26BrFN4O4S, CAS 388082-79-9

N-[3-Bromo-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine

CAS 388082-79-9C₂₉H₂₆BrFN₄O₄S

N-[3-Chloro-4-[(4-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine chemical structure, C29H26ClFN4O4S, CAS 1026818-86-9

N-[3-Chloro-4-[(4-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine

CAS 1026818-86-9C₂₉H₂₆ClFN₄O₄S

5-(4-((3-Chloro-4-(((3-fluorophenyl)methyl)oxy)phenyl)amino)-6-quinazolinyl)-2-furancarbaldehyde mono(4-methylbenzenesulfonate) chemical structure, C33H25ClFN3O6S, CAS 388082-75-5

5-(4-((3-Chloro-4-(((3-fluorophenyl)methyl)oxy)phenyl)amino)-6-quinazolinyl)-2-furancarbaldehyde mono(4-methylbenzenesulfonate)

CAS 388082-75-5C₃₃H₂₅ClFN₃O₆S

(5-(4-(4-((3-Fluorobenzyl)oxy)-3-chloroanilino)-6-quinazolinyl)-2-furancarboxaldehyde chemical structure, C26H17ClFN3O3, CAS 231278-84-5

(5-(4-(4-((3-Fluorobenzyl)oxy)-3-chloroanilino)-6-quinazolinyl)-2-furancarboxaldehyde

CAS 231278-84-5C₂₆H₁₇ClFN₃O₃

Lapatinib ditosylate chemical structure, C43H44ClFN4O11S3, CAS 388082-78-8

Lapatinib ditosylate

CAS 388082-78-8C₄₃H₄₄ClFN₄O₁₁S₃

Tykerb chemical structure, C36H34ClFN4O7S2, CAS 1187538-35-7

CAS 1187538-35-7C₃₆H₃₄ClFN₄O₇S₂

5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde hydrochloride chemical structure, C26H18Cl2FN3O3, CAS 388082-76-6

5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde hydrochloride

CAS 388082-76-6C₂₆H₁₈Cl₂FN₃O₃

5-(4-(4-Benzyloxy-phenylamino)-quinazolin-6-yl)-furan-2-carbaldehyde chemical structure, C26H19N3O3, CAS 202196-46-1

5-(4-(4-Benzyloxy-phenylamino)-quinazolin-6-yl)-furan-2-carbaldehyde

CAS 202196-46-1C₂₆H₁₉N₃O₃

N-Dealkylated lapatinib chemical structure, C26H20ClFN4O2, CAS 697299-82-4

N-Dealkylated lapatinib

CAS 697299-82-4C₂₆H₂₀ClFN₄O₂

Lapatinib impurity 24 chemical structure, C26H18ClN3O3, CAS 231278-83-4

Lapatinib impurity 24

CAS 231278-83-4C₂₆H₁₈ClN₃O₃

Lapatinib impurity 22 chemical structure, C26H18FN3O3, CAS 746591-42-4

Lapatinib impurity 22

CAS 746591-42-4C₂₆H₁₈FN₃O₃

Des(sulfonylethyl)amino Hydroxy Lapatinib chemical structure, C26H19ClFN3O3, CAS 320337-48-2

Des(sulfonylethyl)amino Hydroxy Lapatinib

CAS 320337-48-2C₂₆H₁₉ClFN₃O₃

Lapatinib-d4-1 chemical structure, C29H26ClFN4O4S, CAS 1184264-15-0

CAS 1184264-15-0C₂₉H₂₆ClFN₄O₄S

Lapatinib-d4 chemical structure, C29H26ClFN4O4S, CAS 1184263-99-7

CAS 1184263-99-7C₂₉H₂₆ClFN₄O₄S

N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-(2-methylsulfonylethyliminomethyl)furan-2-yl]quinazolin-4-amine chemical structure, C29H24ClFN4O4S, CAS 1227853-06-6

N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-(2-methylsulfonylethyliminomethyl)furan-2-yl]quinazolin-4-amine

CAS 1227853-06-6C₂₉H₂₄ClFN₄O₄S

2-Furancarboxylic acid, 5-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)- chemical structure, C26H17ClFN3O4, CAS 1152131-73-1

2-Furancarboxylic acid, 5-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-

CAS 1152131-73-1C₂₆H₁₇ClFN₃O₄

Selatinib chemical structure, C29H26ClFN4O3S, CAS 1275595-86-2

CAS 1275595-86-2C₂₉H₂₆ClFN₄O₃S