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Murcko scaffold

Ring system with 4 rings and 24 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
11
With full pages
6
Scaffold SMILES

O=C(Nc1ccc(N2CCNCC2)cc1)c1cc2ccccc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(N2CCNCC2)cc1)c1cc2ccccc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

N-[4-(4-Methylpiperazin-1-yl)phenyl]-1-benzofuran-2-carboxamide chemical structure, C20H21N3O2, CAS 578745-63-8
N-[4-(4-Methylpiperazin-1-yl)phenyl]-1-benzofuran-2-carboxamide
CAS 578745-63-8C20H21N3O2
N-[4-(4-Propanoylpiperazin-1-yl)phenyl]-1-benzofuran-2-carboxamide chemical structure, C22H23N3O3, CAS 688333-52-0
N-[4-(4-Propanoylpiperazin-1-yl)phenyl]-1-benzofuran-2-carboxamide
CAS 688333-52-0C22H23N3O3
N-[4-(4-Methylsulfonylpiperazin-1-yl)phenyl]-1-benzofuran-2-carboxamide chemical structure, C20H21N3O4S, CAS 672344-19-3
N-[4-(4-Methylsulfonylpiperazin-1-yl)phenyl]-1-benzofuran-2-carboxamide
CAS 672344-19-3C20H21N3O4S
N-[4-[4-(2-Methylpropanoyl)piperazin-1-yl]phenyl]-1-benzofuran-2-carboxamide chemical structure, C23H25N3O3, CAS 676157-17-8
N-[4-[4-(2-Methylpropanoyl)piperazin-1-yl]phenyl]-1-benzofuran-2-carboxamide
CAS 676157-17-8C23H25N3O3
Rasarfin chemical structure, C23H24ClN3O3, CAS 674359-73-0
Rasarfin
CAS 674359-73-0C23H24ClN3O3
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-1-benzofuran-2-carboxamide chemical structure, C22H22ClN3O3, CAS 838261-45-3
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-1-benzofuran-2-carboxamide
CAS 838261-45-3C22H22ClN3O3
N-[4-(4-Butyryl-1-piperazinyl)-3-chlorophenyl]-1-benzofuran-2-carboxamide chemical structure, C23H24ClN3O3, CAS 587010-13-7
N-[4-(4-Butyryl-1-piperazinyl)-3-chlorophenyl]-1-benzofuran-2-carboxamide
CAS 587010-13-7C23H24ClN3O3
N-[4-(4-Butyryl-1-piperazinyl)phenyl]-1-benzofuran-2-carboxamide chemical structure, C23H25N3O3, CAS 688333-53-1
N-[4-(4-Butyryl-1-piperazinyl)phenyl]-1-benzofuran-2-carboxamide
CAS 688333-53-1C23H25N3O3
N-[4-(4-Ethylpiperazin-1-yl)phenyl]-1-benzofuran-2-carboxamide chemical structure, C21H23N3O2, CAS 737808-93-4
N-[4-(4-Ethylpiperazin-1-yl)phenyl]-1-benzofuran-2-carboxamide
CAS 737808-93-4C21H23N3O2
N-[4-(4-Acetylpiperazin-1-yl)-3-chlorophenyl]-1-benzofuran-2-carboxamide chemical structure, C21H20ClN3O3, CAS 876898-77-0
N-[4-(4-Acetylpiperazin-1-yl)-3-chlorophenyl]-1-benzofuran-2-carboxamide
CAS 876898-77-0C21H20ClN3O3
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-1-benzofuran-2-carboxamide chemical structure, C24H27N3O3, CAS 895074-90-5
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-1-benzofuran-2-carboxamide
CAS 895074-90-5C24H27N3O3