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Murcko scaffold

Ring system with 3 rings and 18 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
19
With full pages
5
Scaffold SMILES

O=C(Nc1c[nH]c2ccccc12)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1c[nH]c2ccccc12)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

Methyl 3-[(2,6-difluorobenzoyl)amino]-1H-indole-2-carboxylate chemical structure, C17H12F2N2O3, CAS 843628-13-7
Methyl 3-[(2,6-difluorobenzoyl)amino]-1H-indole-2-carboxylate
CAS 843628-13-7C17H12F2N2O3
3-[(2,4,5-Trimethylbenzoyl)amino]-1H-indole-2-carboxylic acid chemical structure, C19H18N2O3, CAS 383900-08-1
3-[(2,4,5-Trimethylbenzoyl)amino]-1H-indole-2-carboxylic acid
CAS 383900-08-1C19H18N2O3
Methyl 3-[(2-fluorobenzoyl)amino]-1H-indole-2-carboxylate chemical structure, C17H13FN2O3, CAS 383904-36-7
Methyl 3-[(2-fluorobenzoyl)amino]-1H-indole-2-carboxylate
CAS 383904-36-7C17H13FN2O3
3-[(4-Fluorobenzoyl)amino]-5-methyl-1H-indole-2-carboxylic acid chemical structure, C17H13FN2O3, CAS 385394-92-3
3-[(4-Fluorobenzoyl)amino]-5-methyl-1H-indole-2-carboxylic acid
CAS 385394-92-3C17H13FN2O3
Methyl 3-[(2,6-difluorobenzoyl)amino]-6-methoxy-1H-indole-2-carboxylate chemical structure, C18H14F2N2O4, CAS 840513-01-1
Methyl 3-[(2,6-difluorobenzoyl)amino]-6-methoxy-1H-indole-2-carboxylate
CAS 840513-01-1C18H14F2N2O4
Ethyl 3-{[3-(trifluoromethyl)benzoyl]amino}-1H-indole-2-carboxylate chemical structure, C19H15F3N2O3, CAS 338968-28-8
Ethyl 3-{[3-(trifluoromethyl)benzoyl]amino}-1H-indole-2-carboxylate
CAS 338968-28-8C19H15F3N2O3
Ethyl 3-(5-chloro-2-methoxybenzamido)-1H-indole-2-carboxylate chemical structure, C19H17ClN2O4, CAS 850929-09-8
Ethyl 3-(5-chloro-2-methoxybenzamido)-1H-indole-2-carboxylate
CAS 850929-09-8C19H17ClN2O4
Ethyl 3-(3,4-dimethylbenzamido)-1H-indole-2-carboxylate chemical structure, C20H20N2O3, CAS 850929-33-8
Ethyl 3-(3,4-dimethylbenzamido)-1H-indole-2-carboxylate
CAS 850929-33-8C20H20N2O3
Ethyl 3-[[4-(diethylsulfamoyl)benzoyl]amino]-1H-indole-2-carboxylate chemical structure, C22H25N3O5S, CAS 850929-70-3
Ethyl 3-[[4-(diethylsulfamoyl)benzoyl]amino]-1H-indole-2-carboxylate
CAS 850929-70-3C22H25N3O5S
Ethyl 3-(2-chloro-5-nitrobenzamido)-1H-indole-2-carboxylate chemical structure, C18H14ClN3O5, CAS 850929-07-6
Ethyl 3-(2-chloro-5-nitrobenzamido)-1H-indole-2-carboxylate
CAS 850929-07-6C18H14ClN3O5
5-Methoxy-3-(2-nitro-benzoylamino)-1H-indole-2-carboxylic acid chemical structure, C17H13N3O6, CAS 385386-37-8
5-Methoxy-3-(2-nitro-benzoylamino)-1H-indole-2-carboxylic acid
CAS 385386-37-8C17H13N3O6
Ethyl 3-(5-chloro-2-nitrobenzamido)-1H-indole-2-carboxylate chemical structure, C18H14ClN3O5, CAS 850929-06-5
Ethyl 3-(5-chloro-2-nitrobenzamido)-1H-indole-2-carboxylate
CAS 850929-06-5C18H14ClN3O5
Ethyl 3-(4-chloro-3-nitrobenzamido)-1H-indole-2-carboxylate chemical structure, C18H14ClN3O5, CAS 850929-56-5
Ethyl 3-(4-chloro-3-nitrobenzamido)-1H-indole-2-carboxylate
CAS 850929-56-5C18H14ClN3O5
3-Benzamido-4,6-dichloro-1H-indole-2-carboxylic acid chemical structure, C16H10Cl2N2O3, CAS 138847-77-5
3-Benzamido-4,6-dichloro-1H-indole-2-carboxylic acid
CAS 138847-77-5C16H10Cl2N2O3
3-(4-Chlorobenzamido)-N-(3-methoxypropyl)-5-methyl-1H-indole-2-carboxamide chemical structure, C21H22ClN3O3, CAS 1031993-73-3
3-(4-Chlorobenzamido)-N-(3-methoxypropyl)-5-methyl-1H-indole-2-carboxamide
CAS 1031993-73-3C21H22ClN3O3
3-(4-Chlorobenzamido)-N-isopentyl-1H-indole-2-carboxamide chemical structure, C21H22ClN3O2, CAS 1031993-88-0
3-(4-Chlorobenzamido)-N-isopentyl-1H-indole-2-carboxamide
CAS 1031993-88-0C21H22ClN3O2
N-(2-Methoxyethyl)-3-(3-methylbenzamido)-1H-indole-2-carboxamide chemical structure, C20H21N3O3, CAS 1029725-17-4
N-(2-Methoxyethyl)-3-(3-methylbenzamido)-1H-indole-2-carboxamide
CAS 1029725-17-4C20H21N3O3
3-(4-Chlorobenzamido)-N-propyl-1H-indole-2-carboxamide chemical structure, C19H18ClN3O2, CAS 1189651-40-8
3-(4-Chlorobenzamido)-N-propyl-1H-indole-2-carboxamide
CAS 1189651-40-8C19H18ClN3O2
N,5-dimethyl-3-[(4-methylbenzoyl)amino]-1H-indole-2-carboxamide chemical structure, C19H19N3O2, CAS 1351398-97-4
N,5-dimethyl-3-[(4-methylbenzoyl)amino]-1H-indole-2-carboxamide
CAS 1351398-97-4C19H19N3O2