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Murcko scaffold

Ring system with 3 rings and 13 atoms

164 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
164
With full pages
22
Scaffold SMILES

C1=CC2c3ccccc3NCC2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=CC2c3ccccc3NCC2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 164 chemicals

8-Methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C14H15NO2, CAS 354815-91-1
8-Methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 354815-91-1C14H15NO2
6,7-Dimethyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C15H17NO2, CAS 935279-96-2
6,7-Dimethyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 935279-96-2C15H17NO2
6-Methoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C14H15NO3, CAS 247225-88-3
6-Methoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 247225-88-3C14H15NO3
6-Hydroxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C13H13NO3, CAS 1415811-61-8
6-Hydroxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 1415811-61-8C13H13NO3
Ethyl (3aR,4S,9bS)-8-bromo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylate chemical structure, C15H16BrNO2
Ethyl (3aR,4S,9bS)-8-bromo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylate
C15H16BrNO2
(3aR,4S,9bS)-8-Chloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C13H12ClNO2, CAS 1212150-55-4
(3aR,4S,9bS)-8-Chloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 1212150-55-4C13H12ClNO2
(3aR,4S,9bS)-8-Methoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C14H15NO3, CAS 1415811-63-0
(3aR,4S,9bS)-8-Methoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 1415811-63-0C14H15NO3
(3aR,4S,9bS)-6,8-Dichloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C13H11Cl2NO2, CAS 1212084-89-3
(3aR,4S,9bS)-6,8-Dichloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 1212084-89-3C13H11Cl2NO2
(3aS,4R,9bR)-8-Acetyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C15H15NO3, CAS 1212255-32-7
(3aS,4R,9bR)-8-Acetyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 1212255-32-7C15H15NO3
(3aR,4S,9bS)-6-Hydroxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C13H13NO3, CAS 676552-83-3
(3aR,4S,9bS)-6-Hydroxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 676552-83-3C13H13NO3
Ethyl (3aS,4S,9bS)-8-bromo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylate chemical structure, C15H16BrNO2
Ethyl (3aS,4S,9bS)-8-bromo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylate
C15H16BrNO2
rac-(3aR,4S,9bS)-6,8-dichloro-3H,3aH,4H,5H,9bH-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C13H11Cl2NO2, CAS 2679949-43-8
rac-(3aR,4S,9bS)-6,8-dichloro-3H,3aH,4H,5H,9bH-cyclopenta[c]quinoline-4-carboxylic acid
CAS 2679949-43-8C13H11Cl2NO2
8-Iodo-6-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C14H14INO2, CAS 353484-33-0
8-Iodo-6-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 353484-33-0C14H14INO2
8-(Ethoxycarbonyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C16H17NO4, CAS 353484-61-4
8-(Ethoxycarbonyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 353484-61-4C16H17NO4
6,8-Dichloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C13H11Cl2NO2, CAS 470693-57-3
6,8-Dichloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 470693-57-3C13H11Cl2NO2
4-Isopropyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic acid chemical structure, C16H19NO2, CAS 354820-37-4
4-Isopropyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic acid
CAS 354820-37-4C16H19NO2
8-Methoxy-6-nitro-4-propan-2-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline chemical structure, C16H20N2O3, CAS 1005137-86-9
8-Methoxy-6-nitro-4-propan-2-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
CAS 1005137-86-9C16H20N2O3
7,9-Dichloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C13H11Cl2NO2, CAS 354809-23-7
7,9-Dichloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 354809-23-7C13H11Cl2NO2
8-(2-Methylpropoxycarbonyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C18H21NO4, CAS 474263-68-8
8-(2-Methylpropoxycarbonyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 474263-68-8C18H21NO4
(3aR,4S,9bS)-Ethyl 8-bromo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylate chemical structure, C15H16BrNO2, CAS 957559-59-0
(3aR,4S,9bS)-Ethyl 8-bromo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylate
CAS 957559-59-0C15H16BrNO2
8-Nitro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C13H12N2O4, CAS 353484-24-9
8-Nitro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 353484-24-9C13H12N2O4
8-Acetamido-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C15H16N2O3, CAS 347362-65-6
8-Acetamido-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 347362-65-6C15H16N2O3
3a,4,5,9b-Tetrahydro-8-methoxy-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C14H15NO3, CAS 247225-89-4
3a,4,5,9b-Tetrahydro-8-methoxy-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 247225-89-4C14H15NO3
6,8-Dimethyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid chemical structure, C15H17NO2, CAS 247225-90-7
6,8-Dimethyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
CAS 247225-90-7C15H17NO2