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Murcko scaffold

Ring system with 3 rings and 14 atoms

169 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
169
With full pages
39
Scaffold SMILES

O=c1oc2ccccc2c2c1CCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1oc2ccccc2c2c1CCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 169 chemicals

7-Dimethylaminocyclopenta[c]coumarin chemical structure, C14H15NO2, CAS 62669-74-3
7-Dimethylaminocyclopenta[c]coumarin
CAS 62669-74-3C14H15NO2
7,9-Dimethoxy-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C14H14O4, CAS 1146-71-0
7,9-Dimethoxy-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 1146-71-0C14H14O4
7-[2-Hydroxy-3-(propylamino)propoxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C18H23NO4, CAS 84229-49-2
7-[2-Hydroxy-3-(propylamino)propoxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 84229-49-2C18H23NO4
6-Methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl N-(tert-butoxycarbonyl)glycinate chemical structure, C20H23NO6, CAS 578757-18-3
6-Methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl N-(tert-butoxycarbonyl)glycinate
CAS 578757-18-3C20H23NO6
4-Oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl 2-[(tert-butoxycarbonyl)amino]butanoate chemical structure, C21H25NO6, CAS 1008463-59-9
4-Oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl 2-[(tert-butoxycarbonyl)amino]butanoate
CAS 1008463-59-9C21H25NO6
Methyl 2-[(7-methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-9-yl)oxy]propanoate chemical structure, C17H18O5, CAS 307549-55-9
Methyl 2-[(7-methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-9-yl)oxy]propanoate
CAS 307549-55-9C17H18O5
4-Oxo-8-propyl-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl acetate chemical structure, C17H18O4, CAS 306321-80-2
4-Oxo-8-propyl-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl acetate
CAS 306321-80-2C17H18O4
(8-Chloro-4-oxo-2,3-dihydro-1H-cyclopenta[c]chromen-7-yl) acetate chemical structure, C14H11ClO4, CAS 304889-94-9
(8-Chloro-4-oxo-2,3-dihydro-1H-cyclopenta[c]chromen-7-yl) acetate
CAS 304889-94-9C14H11ClO4
4-Oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl pivalate chemical structure, C17H18O4, CAS 324055-74-5
4-Oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl pivalate
CAS 324055-74-5C17H18O4
7-[(3-Methylbut-2-enyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C17H18O3, CAS 374703-73-8
7-[(3-Methylbut-2-enyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 374703-73-8C17H18O3
4-Oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl acetate chemical structure, C14H12O4, CAS 21260-40-2
4-Oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl acetate
CAS 21260-40-2C14H12O4
Acetic acid 9-acetoxy-4-oxo-1,2,3,4-tetrahydro-cyclopenta(C)chromen-7-yl ester chemical structure, C16H14O6, CAS 314743-99-2
Acetic acid 9-acetoxy-4-oxo-1,2,3,4-tetrahydro-cyclopenta(C)chromen-7-yl ester
CAS 314743-99-2C16H14O6
6-Methyl-7-((3-methyl-2-butenyl)oxy)-2,3-dihydrocyclopenta(C)chromen-4(1H)-one chemical structure, C18H20O3, CAS 374758-76-6
6-Methyl-7-((3-methyl-2-butenyl)oxy)-2,3-dihydrocyclopenta(C)chromen-4(1H)-one
CAS 374758-76-6C18H20O3
8-Chloro-7-propan-2-yloxy-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-4-one chemical structure, C15H15ClO3, CAS 377765-66-7
8-Chloro-7-propan-2-yloxy-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-4-one
CAS 377765-66-7C15H15ClO3
Diethyl 2,2'-[(4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromene-6,7-diyl)bis(oxy)]diacetate chemical structure, C20H22O8, CAS 670242-23-6
Diethyl 2,2'-[(4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromene-6,7-diyl)bis(oxy)]diacetate
CAS 670242-23-6C20H22O8
6-[(Dimethylazaniumyl)methyl]-4-oxo-2,3-dihydro-1H-cyclopenta[c]chromen-7-olate chemical structure, C15H17NO3, CAS 5729-82-8
6-[(Dimethylazaniumyl)methyl]-4-oxo-2,3-dihydro-1H-cyclopenta[c]chromen-7-olate
CAS 5729-82-8C15H17NO3
8-Chloro-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl N-(tert-butoxycarbonyl)-beta-alaninate chemical structure, C20H22ClNO6, CAS 301227-31-6
8-Chloro-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl N-(tert-butoxycarbonyl)-beta-alaninate
CAS 301227-31-6C20H22ClNO6
Ethyl 2-(4-oxo-1,2,3-trihydrocyclopenta[1,2-c]chromen-7-yloxy)acetate chemical structure, C16H16O5, CAS 298207-30-4
Ethyl 2-(4-oxo-1,2,3-trihydrocyclopenta[1,2-c]chromen-7-yloxy)acetate
CAS 298207-30-4C16H16O5
4-Oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl N-(tert-butoxycarbonyl)-beta-alaninate chemical structure, C20H23NO6, CAS 307526-39-2
4-Oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl N-(tert-butoxycarbonyl)-beta-alaninate
CAS 307526-39-2C20H23NO6
Dimethyl 2,2'-[(4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromene-7,9-diyl)bis(oxy)]diacetate chemical structure, C18H18O8, CAS 301304-69-8
Dimethyl 2,2'-[(4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromene-7,9-diyl)bis(oxy)]diacetate
CAS 301304-69-8C18H18O8
(6-Methyl-4-oxo-1,2,3,4-tetrahydro-cyclopenta[c]chromen-7-yloxy)-acetonitrile chemical structure, C15H13NO3, CAS 449737-10-4
(6-Methyl-4-oxo-1,2,3,4-tetrahydro-cyclopenta[c]chromen-7-yloxy)-acetonitrile
CAS 449737-10-4C15H13NO3
4-Oxo-8-propyl-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl N-(tert-butoxycarbonyl)-beta-alaninate chemical structure, C23H29NO6, CAS 301308-29-2
4-Oxo-8-propyl-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl N-(tert-butoxycarbonyl)-beta-alaninate
CAS 301308-29-2C23H29NO6
Butyl [(4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy]acetate chemical structure, C18H20O5, CAS 301308-96-3
Butyl [(4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy]acetate
CAS 301308-96-3C18H20O5
Diethyl 2,2'-((4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromene-7,9-diyl)bis(oxy))diacetate chemical structure, C20H22O8, CAS 307549-27-5
Diethyl 2,2'-((4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromene-7,9-diyl)bis(oxy))diacetate
CAS 307549-27-5C20H22O8