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Murcko scaffold

2-(Naphthalen-2-yloxy)-1-piperazin-1-yl-ethanone scaffold

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
11
With full pages
4
Scaffold SMILES

O=C(COc1ccc2ccccc2c1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Naphthalen-2-yloxy)-1-piperazin-1-yl-ethanone page
Murcko scaffold O=C(COc1ccc2ccccc2c1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

1-(4-Methylsulfonylpiperazin-1-yl)-2-naphthalen-2-yloxyethanone chemical structure, C17H20N2O4S, CAS 333756-35-7
1-(4-Methylsulfonylpiperazin-1-yl)-2-naphthalen-2-yloxyethanone
CAS 333756-35-7C17H20N2O4S
2-(Naphthalen-2-yloxy)-1-piperazin-1-yl-ethanone chemical structure, C16H18N2O2, CAS 462066-92-8
2-(Naphthalen-2-yloxy)-1-piperazin-1-yl-ethanone
CAS 462066-92-8C16H18N2O2
2-Naphthalen-2-yloxy-1-(4-propan-2-ylpiperazin-1-yl)ethanone chemical structure, C19H24N2O2, CAS 423738-63-0
2-Naphthalen-2-yloxy-1-(4-propan-2-ylpiperazin-1-yl)ethanone
CAS 423738-63-0C19H24N2O2
Ethyl 4-(2-naphthalen-2-yloxyacetyl)piperazine-1-carboxylate chemical structure, C19H22N2O4, CAS 6134-46-9
Ethyl 4-(2-naphthalen-2-yloxyacetyl)piperazine-1-carboxylate
CAS 6134-46-9C19H22N2O4
4-(2-Naphthalen-2-yloxyacetyl)piperazine-1-carbaldehyde chemical structure, C17H18N2O3, CAS 378214-66-5
4-(2-Naphthalen-2-yloxyacetyl)piperazine-1-carbaldehyde
CAS 378214-66-5C17H18N2O3
1-(4-Ethylpiperazin-1-yl)-2-naphthalen-2-yloxyethanone chemical structure, C18H22N2O2, CAS 445250-07-7
1-(4-Ethylpiperazin-1-yl)-2-naphthalen-2-yloxyethanone
CAS 445250-07-7C18H22N2O2
1-(4-Methylpiperazin-1-yl)-2-(naphthalen-2-yloxy)ethanone chemical structure, C17H20N2O2, CAS 549489-79-4
1-(4-Methylpiperazin-1-yl)-2-(naphthalen-2-yloxy)ethanone
CAS 549489-79-4C17H20N2O2
2-Naphthalen-2-yloxy-1-(4-propylsulfonylpiperazin-1-yl)ethanone chemical structure, C19H24N2O4S, CAS 428850-13-9
2-Naphthalen-2-yloxy-1-(4-propylsulfonylpiperazin-1-yl)ethanone
CAS 428850-13-9C19H24N2O4S
3-Methyl-1-[4-(2-naphthalen-2-yloxyacetyl)piperazin-1-yl]butan-1-one chemical structure, C21H26N2O3, CAS 333756-10-8
3-Methyl-1-[4-(2-naphthalen-2-yloxyacetyl)piperazin-1-yl]butan-1-one
CAS 333756-10-8C21H26N2O3
Ethyl 4-{[(1-bromo-2-naphthyl)oxy]acetyl}-1-piperazinecarboxylate chemical structure, C19H21BrN2O4, CAS 650588-11-7
Ethyl 4-{[(1-bromo-2-naphthyl)oxy]acetyl}-1-piperazinecarboxylate
CAS 650588-11-7C19H21BrN2O4
2-(Naphthalen-2-yloxy)-1-(piperazin-1-yl)ethanone 2,2,2-trifluoroacetate chemical structure, C18H19F3N2O4, CAS 1135289-91-6
2-(Naphthalen-2-yloxy)-1-(piperazin-1-yl)ethanone 2,2,2-trifluoroacetate
CAS 1135289-91-6C18H19F3N2O4