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Murcko scaffold

2-(3-Oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)-N-phenylacetamide scaffold

58 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
58
With full pages
11
Scaffold SMILES

O=C(Cn1nc2c(cc1=O)CCCC2)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(3-Oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)-N-phenylacetamide page
Murcko scaffold O=C(Cn1nc2c(cc1=O)CCCC2)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 58 chemicals

N-(4-Fluorophenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C16H16FN3O2, CAS 869463-98-9
N-(4-Fluorophenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 869463-98-9C16H16FN3O2
N-(3-Bromophenyl)-2-(3-oxo-2,3,5,6,7,8-hexahydrocinnolin-2-yl)acetamide chemical structure, C16H16BrN3O2, CAS 863420-06-8
N-(3-Bromophenyl)-2-(3-oxo-2,3,5,6,7,8-hexahydrocinnolin-2-yl)acetamide
CAS 863420-06-8C16H16BrN3O2
N-(3-Chloro-4-methoxyphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C17H18ClN3O3, CAS 923238-61-3
N-(3-Chloro-4-methoxyphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 923238-61-3C17H18ClN3O3
N-(2,5-Dimethoxyphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C18H21N3O4, CAS 931361-69-2
N-(2,5-Dimethoxyphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 931361-69-2C18H21N3O4
N-Mesityl-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C19H23N3O2, CAS 932971-91-0
N-Mesityl-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 932971-91-0C19H23N3O2
N-(2,4-Difluorophenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C16H15F2N3O2, CAS 933027-94-2
N-(2,4-Difluorophenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 933027-94-2C16H15F2N3O2
Ethyl 3-[2-(3-oxo-2,3,5,6,7,8-hexahydrocinnolin-2-yl)acetamido]benzoate chemical structure, C19H21N3O4, CAS 932972-11-7
Ethyl 3-[2-(3-oxo-2,3,5,6,7,8-hexahydrocinnolin-2-yl)acetamido]benzoate
CAS 932972-11-7C19H21N3O4
2-(3-Oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)-N-(2-(trifluoromethyl)phenyl)acetamide chemical structure, C17H16F3N3O2, CAS 933238-14-3
2-(3-Oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)-N-(2-(trifluoromethyl)phenyl)acetamide
CAS 933238-14-3C17H16F3N3O2
N-(3-Chloro-4-methylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C17H18ClN3O2, CAS 933238-18-7
N-(3-Chloro-4-methylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 933238-18-7C17H18ClN3O2
2-(6-Methyl-3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)-N-(3,4,5-trimethoxyphenyl)acetamide chemical structure, C20H25N3O5, CAS 933005-40-4
2-(6-Methyl-3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)-N-(3,4,5-trimethoxyphenyl)acetamide
CAS 933005-40-4C20H25N3O5
N-(4-Ethoxyphenyl)-2-(6-methyl-3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C19H23N3O3, CAS 933238-67-6
N-(4-Ethoxyphenyl)-2-(6-methyl-3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 933238-67-6C19H23N3O3
N-(5-Chloro-2-methylphenyl)-2-(6-methyl-3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C18H20ClN3O2, CAS 932997-71-2
N-(5-Chloro-2-methylphenyl)-2-(6-methyl-3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 932997-71-2C18H20ClN3O2
2-(6-Methyl-3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)-N-(3-(trifluoromethyl)phenyl)acetamide chemical structure, C18H18F3N3O2, CAS 932997-83-6
2-(6-Methyl-3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)-N-(3-(trifluoromethyl)phenyl)acetamide
CAS 932997-83-6C18H18F3N3O2
N-(4-Bromophenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C16H16BrN3O2, CAS 932972-27-5
N-(4-Bromophenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 932972-27-5C16H16BrN3O2
2-(3-Oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)-N-(o-tolyl)acetamide chemical structure, C17H19N3O2, CAS 941934-17-4
2-(3-Oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)-N-(o-tolyl)acetamide
CAS 941934-17-4C17H19N3O2
N-(5-Chloro-2-methoxyphenyl)-2-(3-oxo-2,3,5,6,7,8-hexahydrocinnolin-2-yl)acetamide chemical structure, C17H18ClN3O3, CAS 933238-22-3
N-(5-Chloro-2-methoxyphenyl)-2-(3-oxo-2,3,5,6,7,8-hexahydrocinnolin-2-yl)acetamide
CAS 933238-22-3C17H18ClN3O3
2-(3-Oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)-N-phenylacetamide chemical structure, C16H17N3O2, CAS 933027-76-0
2-(3-Oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)-N-phenylacetamide
CAS 933027-76-0C16H17N3O2
N-(4-Ethoxyphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C18H21N3O3, CAS 932972-03-7
N-(4-Ethoxyphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 932972-03-7C18H21N3O3
N-(5-Chloro-2-methylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C17H18ClN3O2, CAS 933237-92-4
N-(5-Chloro-2-methylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 933237-92-4C17H18ClN3O2
N-(4-Chloro-2-methoxy-5-methylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C18H20ClN3O3, CAS 933238-02-9
N-(4-Chloro-2-methoxy-5-methylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 933238-02-9C18H20ClN3O3
N-(5-Chloro-2,4-dimethoxyphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C18H20ClN3O4, CAS 933028-21-8
N-(5-Chloro-2,4-dimethoxyphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 933028-21-8C18H20ClN3O4
N-(3-Ethylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C18H21N3O2, CAS 933028-00-3
N-(3-Ethylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 933028-00-3C18H21N3O2
N-(2-Methoxy-5-methylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C18H21N3O3, CAS 932972-19-5
N-(2-Methoxy-5-methylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 932972-19-5C18H21N3O3
N-(4-Acetylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide chemical structure, C18H19N3O3, CAS 933028-06-9
N-(4-Acetylphenyl)-2-(3-oxo-5,6,7,8-tetrahydrocinnolin-2(3H)-yl)acetamide
CAS 933028-06-9C18H19N3O3