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Murcko scaffold

Ring system with 3 rings and 16 atoms

19 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 16
Chemicals: 19
With full pages: 5

Scaffold SMILES

O=c1c(-c2nccs2)coc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1c(-c2nccs2)coc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

7-Methoxy-5-methyl-3-(4-methyl-1,3-thiazol-2-yl)-4H-chromen-4-one chemical structure, C15H13NO3S, CAS 292053-14-6

7-Methoxy-5-methyl-3-(4-methyl-1,3-thiazol-2-yl)-4H-chromen-4-one

CAS 292053-14-6C₁₅H₁₃NO₃S

6-Ethyl-2-methyl-3-(4-methylthiazol-2-yl)-4-oxo-4H-chromen-7-yl acetate chemical structure, C18H17NO4S, CAS 374700-64-8

6-Ethyl-2-methyl-3-(4-methylthiazol-2-yl)-4-oxo-4H-chromen-7-yl acetate

CAS 374700-64-8C₁₈H₁₇NO₄S

7-Ethoxy-6-ethyl-3-(4-methyl-1,3-thiazol-2-yl)-4H-chromen-4-one chemical structure, C17H17NO3S, CAS 306288-78-8

7-Ethoxy-6-ethyl-3-(4-methyl-1,3-thiazol-2-yl)-4H-chromen-4-one

CAS 306288-78-8C₁₇H₁₇NO₃S

8-[(Dimethylamino)methyl]-6-ethyl-7-hydroxy-3-(4-methyl-1,3-thiazol-2-yl)-4H-chromen-4-one chemical structure, C18H20N2O3S, CAS 383386-75-2

8-[(Dimethylamino)methyl]-6-ethyl-7-hydroxy-3-(4-methyl-1,3-thiazol-2-yl)-4H-chromen-4-one

CAS 383386-75-2C₁₈H₂₀N₂O₃S

2-Methyl-3-(4-methylthiazol-2-yl)-4-oxo-6-propyl-4H-chromen-7-yl acetate chemical structure, C19H19NO4S, CAS 299952-22-0

2-Methyl-3-(4-methylthiazol-2-yl)-4-oxo-6-propyl-4H-chromen-7-yl acetate

CAS 299952-22-0C₁₉H₁₉NO₄S

Methyl 2-[6-ethyl-3-(4-methyl-1,3-thiazol-2-yl)-4-oxochromen-7-yl]oxyacetate chemical structure, C18H17NO5S, CAS 374704-60-6

Methyl 2-[6-ethyl-3-(4-methyl-1,3-thiazol-2-yl)-4-oxochromen-7-yl]oxyacetate

CAS 374704-60-6C₁₈H₁₇NO₅S

Ethyl {[5-methyl-3-(4-methyl-1,3-thiazol-2-yl)-4-oxo-4H-chromen-7-yl]oxy}acetate chemical structure, C18H17NO5S, CAS 292053-13-5

Ethyl {[5-methyl-3-(4-methyl-1,3-thiazol-2-yl)-4-oxo-4H-chromen-7-yl]oxy}acetate

CAS 292053-13-5C₁₈H₁₇NO₅S

6-Ethyl-3-(4-methyl-2-thiazolyl)-4-oxo-4H-1-benzopyran-7-yl 6-aminohexanoate chemical structure, C21H24N2O4S, CAS 919741-66-5

6-Ethyl-3-(4-methyl-2-thiazolyl)-4-oxo-4H-1-benzopyran-7-yl 6-aminohexanoate

CAS 919741-66-5C₂₁H₂₄N₂O₄S

Ethyl 2-((6-ethyl-3-(4-methylthiazol-2-yl)-4-oxo-4H-chromen-7-yl)oxy)propanoate chemical structure, C20H21NO5S, CAS 170466-93-0

Ethyl 2-((6-ethyl-3-(4-methylthiazol-2-yl)-4-oxo-4H-chromen-7-yl)oxy)propanoate

CAS 170466-93-0C₂₀H₂₁NO₅S

2,6-Diethyl-3-(4-methylthiazol-2-yl)-4-oxo-4H-chromen-7-yl propionate chemical structure, C20H21NO4S, CAS 315237-70-8

2,6-Diethyl-3-(4-methylthiazol-2-yl)-4-oxo-4H-chromen-7-yl propionate

CAS 315237-70-8C₂₀H₂₁NO₄S

6-Ethyl-2-isopropyl-3-(4-methylthiazol-2-yl)-4-oxo-4H-chromen-7-yl isobutyrate chemical structure, C22H25NO4S, CAS 308297-72-5

6-Ethyl-2-isopropyl-3-(4-methylthiazol-2-yl)-4-oxo-4H-chromen-7-yl isobutyrate

CAS 308297-72-5C₂₂H₂₅NO₄S

7-Hydroxy-6-methyl-3-(4-methyl-1,3-thiazol-2-yl)-2-(trifluoromethyl)-4H-chromen-4-one chemical structure, C15H10F3NO3S, CAS 170466-89-4

7-Hydroxy-6-methyl-3-(4-methyl-1,3-thiazol-2-yl)-2-(trifluoromethyl)-4H-chromen-4-one

CAS 170466-89-4C₁₅H₁₀F₃NO₃S

6-Ethyl-7-hydroxy-3-(4-methylthiazol-2-yl)-4H-chromen-4-one chemical structure, C15H13NO3S, CAS 170466-84-9

6-Ethyl-7-hydroxy-3-(4-methylthiazol-2-yl)-4H-chromen-4-one

CAS 170466-84-9C₁₅H₁₃NO₃S

7-Hydroxy-3-(4-methyl-1,3-thiazol-2-yl)-6-propyl-4H-chromen-4-one chemical structure, C16H15NO3S, CAS 137812-01-2

7-Hydroxy-3-(4-methyl-1,3-thiazol-2-yl)-6-propyl-4H-chromen-4-one

CAS 137812-01-2C₁₆H₁₅NO₃S

6-Ethyl-7-hydroxy-3-(4-methyl-1,3-thiazol-2-yl)-4-oxo-4H-chromene-2-carboxylic acid chemical structure, C16H13NO5S, CAS 374697-97-9

6-Ethyl-7-hydroxy-3-(4-methyl-1,3-thiazol-2-yl)-4-oxo-4H-chromene-2-carboxylic acid

CAS 374697-97-9C₁₆H₁₃NO₅S

6-Ethyl-7-hydroxy-2-methyl-3-(4-methyl-1,3-thiazol-2-yl)-4H-chromen-4-one chemical structure, C16H15NO3S, CAS 374699-31-7

6-Ethyl-7-hydroxy-2-methyl-3-(4-methyl-1,3-thiazol-2-yl)-4H-chromen-4-one

CAS 374699-31-7C₁₆H₁₅NO₃S

3-(6-Ethyl-7-hydroxy-3-(4-methylthiazol-2-yl)-4-oxo-4H-chromen-2-yl)propanoic acid chemical structure, C18H17NO5S, CAS 300557-67-9

3-(6-Ethyl-7-hydroxy-3-(4-methylthiazol-2-yl)-4-oxo-4H-chromen-2-yl)propanoic acid

CAS 300557-67-9C₁₈H₁₇NO₅S

4-[6-Ethyl-7-hydroxy-3-(4-methyl-1,3-thiazol-2-yl)-4-oxo-4H-chromen-2-yl]butanoic acid chemical structure, C19H19NO5S, CAS 405921-45-1

4-[6-Ethyl-7-hydroxy-3-(4-methyl-1,3-thiazol-2-yl)-4-oxo-4H-chromen-2-yl]butanoic acid

CAS 405921-45-1C₁₉H₁₉NO₅S

6-Butyl-7-hydroxy-3-(4-methyl-2-thiazolyl)-4H-1-benzopyran-4-one chemical structure, C17H17NO3S, CAS 170466-86-1

6-Butyl-7-hydroxy-3-(4-methyl-2-thiazolyl)-4H-1-benzopyran-4-one

CAS 170466-86-1C₁₇H₁₇NO₃S