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Murcko scaffold

2,3,5,7A-Tetrahydro-1H-pyrrolizine scaffold

131 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
131
With full pages
44
Scaffold SMILES

C1=CC2CCCN2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3,5,7A-Tetrahydro-1H-pyrrolizine page
Murcko scaffold C1=CC2CCCN2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 131 chemicals

Heliotridine, 7,9-dipivalate chemical structure, C18H29NO4, CAS 59532-51-3
Heliotridine, 7,9-dipivalate
CAS 59532-51-3C18H29NO4
7-Acetylintermedine chemical structure, C17H27NO6, CAS 74243-01-9
7-Acetylintermedine
CAS 74243-01-9C17H27NO6
1H-Pyrrolizin-1-ol, 7-(chloromethyl)-2,3,5,7a-tetrahydro-, (1S-cis)- chemical structure, C8H12ClNO, CAS 59518-71-7
1H-Pyrrolizin-1-ol, 7-(chloromethyl)-2,3,5,7a-tetrahydro-, (1S-cis)-
CAS 59518-71-7C8H12ClNO
(1S,7aR)-2,3,5,7a-Tetrahydro-7-(hydroxymethyl)-1H-pyrrolizin-1-yl (2Z)-2-methyl-2-butenoate chemical structure, C13H19NO3, CAS 723-78-4
(1S,7aR)-2,3,5,7a-Tetrahydro-7-(hydroxymethyl)-1H-pyrrolizin-1-yl (2Z)-2-methyl-2-butenoate
CAS 723-78-4C13H19NO3
Echimidine chemical structure, C20H31NO7, CAS 520-68-3
Echimidine
CAS 520-68-3C20H31NO7
Heliosupine chemical structure, C20H31NO7, CAS 32728-78-2
Heliosupine
CAS 32728-78-2C20H31NO7
Lasiocarpine chemical structure, C21H33NO7, CAS 303-34-4
Lasiocarpine
CAS 303-34-4C21H33NO7
Symlandine chemical structure, C20H31NO6, CAS 74410-74-5
Symlandine
CAS 74410-74-5C20H31NO6
Symphytine chemical structure, C20H31NO6, CAS 22571-95-5
Symphytine
CAS 22571-95-5C20H31NO6
Triangularine chemical structure, C18H25NO5, CAS 87340-27-0
Triangularine
CAS 87340-27-0C18H25NO5
Lasiocarpine impurity 2 chemical structure, C21H33NO8
Lasiocarpine impurity 2
C21H33NO8
[(1R,7aS)-1-Hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl]methyl (2S,3R)-2-hydroxy-3-methoxy-2-(propan-2-yl)butanoate chemical structure, C16H27NO5
[(1R,7aS)-1-Hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl]methyl (2S,3R)-2-hydroxy-3-methoxy-2-(propan-2-yl)butanoate
C16H27NO5
Heliotrine, N-oxide chemical structure, C16H27NO6, CAS 6209-65-0
Heliotrine, N-oxide
CAS 6209-65-0C16H27NO6
[(1S,7AR)-1-hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl]methyl (2R,3R)-2-hydroxy-2-isopropyl-3-methoxybutanoate chemical structure, C16H27NO5
[(1S,7AR)-1-hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl]methyl (2R,3R)-2-hydroxy-2-isopropyl-3-methoxybutanoate
C16H27NO5
Heliotridine, (-)- chemical structure, C8H13NO2, CAS 74431-30-4
Heliotridine, (-)-
CAS 74431-30-4C8H13NO2
Lasiocarpine N-oxide chemical structure, C21H33NO8, CAS 127-30-0
Lasiocarpine N-oxide
CAS 127-30-0C21H33NO8
Europine chemical structure, C16H27NO6, CAS 570-19-4
Europine
CAS 570-19-4C16H27NO6
Europine oxide chemical structure, C16H27NO7, CAS 65582-53-8
Europine oxide
CAS 65582-53-8C16H27NO7
Isatinecine chemical structure, C8H13NO3, CAS 6870-33-3
Isatinecine
CAS 6870-33-3C8H13NO3
3'-Acetylheliosupine chemical structure, C22H33NO8, CAS 31514-30-4
3'-Acetylheliosupine
CAS 31514-30-4C22H33NO8
2-Butenoic acid, 2-methyl, 2,3,5,7a-tetrahydro-7-(hydroxymethyl)-1H-pyrrolizin-1-yl ester, hydrochloride, (Z)- chemical structure, C13H20ClNO3, CAS 887-66-1
2-Butenoic acid, 2-methyl, 2,3,5,7a-tetrahydro-7-(hydroxymethyl)-1H-pyrrolizin-1-yl ester, hydrochloride, (Z)-
CAS 887-66-1C13H20ClNO3
Lasiocarpine hydrochloride chemical structure, C21H34ClNO7, CAS 1976-49-4
Lasiocarpine hydrochloride
CAS 1976-49-4C21H34ClNO7
Scorpioidine chemical structure, C20H31NO6, CAS 80405-18-1
Scorpioidine
CAS 80405-18-1C20H31NO6
7-Acetylscorpioidine chemical structure, C22H33NO7, CAS 80405-17-0
7-Acetylscorpioidine
CAS 80405-17-0C22H33NO7