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Murcko scaffold

2,3,5,7A-Tetrahydro-1H-pyrrolizine scaffold

131 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
131
With full pages
44
Scaffold SMILES

C1=CC2CCCN2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3,5,7A-Tetrahydro-1H-pyrrolizine page
Murcko scaffold C1=CC2CCCN2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 131 of 131 chemicals

1H-Pyrrolizin-1-ol, 2,3,5,7a-tetrahydro-7-(methoxymethyl)-, (1R-trans)- chemical structure, C9H15NO2, CAS 24999-22-2
1H-Pyrrolizin-1-ol, 2,3,5,7a-tetrahydro-7-(methoxymethyl)-, (1R-trans)-
CAS 24999-22-2C9H15NO2
7,9-Ditigloylretronecine chemical structure, C18H25NO4, CAS 25471-38-9
7,9-Ditigloylretronecine
CAS 25471-38-9C18H25NO4
Heliosupine N-oxide chemical structure, C20H31NO8
Heliosupine N-oxide
C20H31NO8
Echimidine N-oxide chemical structure, C20H31NO8, CAS 41093-89-4
Echimidine N-oxide
CAS 41093-89-4C20H31NO8
(7-Hydroxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl)methyl N-ethylcarbamate chemical structure, C11H18N2O3
(7-Hydroxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl)methyl N-ethylcarbamate
C11H18N2O3
2-Butenoic acid, 2-methyl-, (2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (1R-(1alpha,7(E),7abeta))- chemical structure, C13H19NO3, CAS 63128-42-7
2-Butenoic acid, 2-methyl-, (2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (1R-(1alpha,7(E),7abeta))-
CAS 63128-42-7C13H19NO3
7-Angeloylrinderine chemical structure, C20H31NO6, CAS 116913-25-8
7-Angeloylrinderine
CAS 116913-25-8C20H31NO6
[(1R,7aR)-2,3,5,7a-Tetrahydro-1-hydroxy-4-oxido-1H-pyrrolizin-7-yl]methyl (2R)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate chemical structure, C15H25NO6, CAS 95462-16-1
[(1R,7aR)-2,3,5,7a-Tetrahydro-1-hydroxy-4-oxido-1H-pyrrolizin-7-yl]methyl (2R)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate
CAS 95462-16-1C15H25NO6
[(7S,8R)-7-[(E)-2-Methylbut-2-enoyl]oxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl (2R)-2,3-dihydroxy-2-[(1R)-1-methoxyethyl]-3-methylbutanoate chemical structure, C21H33NO8
[(7S,8R)-7-[(E)-2-Methylbut-2-enoyl]oxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl (2R)-2,3-dihydroxy-2-[(1R)-1-methoxyethyl]-3-methylbutanoate
C21H33NO8
Otonecine chemical structure, C9H16NO3+, CAS 6887-34-9
Otonecine
CAS 6887-34-9C9H16NO3+
Echiumine N-oxide chemical structure, C20H31NO7, CAS 685554-68-1
Echiumine N-oxide
CAS 685554-68-1C20H31NO7
Amabiline N-oxide chemical structure, C15H25NO5, CAS 145265-23-2
Amabiline N-oxide
CAS 145265-23-2C15H25NO5
Anadoline chemical structure, C20H31NO7, CAS 28513-29-3
Anadoline
CAS 28513-29-3C20H31NO7
[(7S,7aR)-7-Hydroxy-4-oxo-3,4,5,6,7,7a-hexahydro-4lambda5-pyrrolizin-1-yl]methyl (2S)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate chemical structure, C15H25NO6, CAS 137821-16-0
[(7S,7aR)-7-Hydroxy-4-oxo-3,4,5,6,7,7a-hexahydro-4lambda5-pyrrolizin-1-yl]methyl (2S)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate
CAS 137821-16-0C15H25NO6
Othonecine chloride chemical structure, C9H16ClNO3, CAS 7201-79-8
Othonecine chloride
CAS 7201-79-8C9H16ClNO3
Triacetylindicine chemical structure, C21H31NO8, CAS 39870-08-1
Triacetylindicine
CAS 39870-08-1C21H31NO8
7-Angelylheliotrine chemical structure, C21H33NO6, CAS 56317-17-0
7-Angelylheliotrine
CAS 56317-17-0C21H33NO6
((1R,7AS)-1-hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl)methyl ethylcarbamate chemical structure, C11H18N2O3
((1R,7AS)-1-hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl)methyl ethylcarbamate
C11H18N2O3
Intermedine monoacetate chemical structure, C17H29NO7, CAS 55529-83-4
Intermedine monoacetate
CAS 55529-83-4C17H29NO7
Indicine hydrochloride chemical structure, C15H26ClNO5, CAS 1195140-94-3
Indicine hydrochloride
CAS 1195140-94-3C15H26ClNO5
Europin N-oxide, HPLC Grade chemical structure, C16H27NO7
Europin N-oxide, HPLC Grade
C16H27NO7
Lasiocarpine-N-oxide chemical structure, C21H33NO8
Lasiocarpine-N-oxide
C21H33NO8
(7-Hydroxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl)methyl 3-hydroxy-2,4-dimethyl-5-(2-methylbut-2-enoyloxy)pentanoate chemical structure, C20H31NO7
(7-Hydroxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl)methyl 3-hydroxy-2,4-dimethyl-5-(2-methylbut-2-enoyloxy)pentanoate
C20H31NO7
Lasiocarpine N-oxide, HPLC Grade chemical structure, C21H33NO8
Lasiocarpine N-oxide, HPLC Grade
C21H33NO8