Murcko scaffold
Isoxazole scaffold
5,682 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 5
- Chemicals
- 5,682
- With full pages
- 801
Scaffold SMILES
c1cnoc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1,249 to 1,296 of 5,682 chemicals
3-Propyl-1,2-oxazole-5-carboxylic acid
CAS 14716-92-8C7H9NO3
5-(Aminomethyl)-1,2-oxazole-3-carboxylic acid
CAS 138741-50-1C5H6N2O3
![Ethyl 5-[(methylamino)methyl]isoxazole-3-carboxylate chemical structure, C8H12N2O3, CAS 897094-85-8](/s/CSBSCGZWKOWOPY-UHFFFAOYSA-N.svg)
Ethyl 5-[(methylamino)methyl]isoxazole-3-carboxylate
CAS 897094-85-8C8H12N2O3
![5-[(Methylamino)methyl]-1,2-oxazole-3-carboxylic acid chemical structure, C6H8N2O3, CAS 893749-64-9](/s/YLWTUVGTHMKNAO-UHFFFAOYSA-N.svg)
5-[(Methylamino)methyl]-1,2-oxazole-3-carboxylic acid
CAS 893749-64-9C6H8N2O3
![5-[(Ethylamino)methyl]-1,2-oxazole-3-carboxylic acid chemical structure, C7H10N2O3, CAS 893749-72-9](/s/RSLCLEQPHNHZPQ-UHFFFAOYSA-N.svg)
5-[(Ethylamino)methyl]-1,2-oxazole-3-carboxylic acid
CAS 893749-72-9C7H10N2O3
N,N-Dimethyl-1-(3-((methylamino)methyl)isoxazol-5-yl)methanamine
CAS 893748-74-8C8H15N3O
(5-(Methoxymethyl)isoxazol-3-yl)methanamine
CAS 893749-21-8C6H10N2O2
(5-(Ethoxymethyl)isoxazol-3-yl)methanamine
CAS 893749-25-2C7H12N2O2
1-(5-(Methoxymethyl)isoxazol-3-yl)-N-methylmethanamine
CAS 893749-33-2C7H12N2O2
![5-[(Dimethylamino)methyl]-1,2-oxazole-3-carbaldehyde chemical structure, C7H10N2O2, CAS 893749-69-4](/s/XAIIKHPABHSAAX-UHFFFAOYSA-N.svg)
5-[(Dimethylamino)methyl]-1,2-oxazole-3-carbaldehyde
CAS 893749-69-4C7H10N2O2
5-(Methoxymethyl)-1,2-oxazole-3-carbaldehyde
CAS 893749-91-2C6H7NO3
![4-[(Dimethylamino)methyl]-5-methyl-3-isoxazolecarboxaldehyde chemical structure, C8H12N2O2, CAS 893751-53-6](/s/HRWIILVIZMHURG-UHFFFAOYSA-N.svg)
4-[(Dimethylamino)methyl]-5-methyl-3-isoxazolecarboxaldehyde
CAS 893751-53-6C8H12N2O2
5-((Dimethylamino)methyl)isoxazole-3-carboxylic acid
CAS 893749-80-9C7H10N2O3
5-Bromo-1,2-oxazole
CAS 1133930-99-0C3H2BrNO
3,5-Diethylisoxazole-4-carbonyl chloride
CAS 2101973-29-7C8H10ClNO2
3-Ethyl-5-methylisoxazole-4-carbonyl chloride
CAS 99298-90-5C7H8ClNO2
5-(Trifluoromethyl)isoxazole-4-carboxylic acid
CAS 1094702-34-7C5H2F3NO3
4-Isopropylisoxazole
CAS 98196-66-8C6H9NO
N-(4-Chloro-3-nonyl-1,2-oxazol-5-yl)acetamide
CAS 92088-05-6C14H23ClN2O2
5-(1-Chloroethyl)-3-methyl-1,2-oxazole
CAS 63820-94-0C6H8ClNO
4-Chloro-5-(chloromethyl)-3-methylisoxazole
CAS 69711-41-7C5H5Cl2NO
4-(Chloromethyl)-3-methyl-1,2-oxazole
CAS 99979-76-7C5H6ClNO
3-(1-Chloroethyl)isoxazole
CAS 69711-46-2C5H6ClNO
2-(3-Methoxy-1,2-oxazol-5-yl)acetic acid
CAS 16877-55-7C6H7NO4
- 1-(1,2-Oxazol-5-yl)ethan-1-one88511-38-0C5H5NO2
- 4-Nitro-1,2-oxazol-3-amine1314909-53-9C3H3N3O3
- N-Methyl-1,2-oxazol-3-amine55809-39-7C4H6N2O
- 5-Methylisoxazol-3-amine hydrochloride60959-25-3C4H7ClN2O
- 3-Ethyl-N,5-dimethyl-1,2-oxazole-4-carboxamide62613-74-5C8H12N2O2
- 4-Isoxazolecarbonitrile, 5-amino-3-(methylthio)-68571-72-2C5H5N3OS
- N'-(5-tert-Butyl-1,2-oxazol-3-yl)-N,N-diethylurea55808-37-2C12H21N3O2
- N'-(5-tert-Butyl-1,2-oxazol-3-yl)-N-ethyl-N-methylurea55808-36-1C11H19N3O2
- 1-(4-Nitro-5-tetradecyl-1,2-oxazol-3-yl)pentadecan-1-one65474-86-4C32H58N2O4
- N-Carbamoylisoxazole-3-carboxamide32954-29-3C5H5N3O3
- 2-[[(3,5-Dimethyl-4-isoxazolyl)methyl]thio]ethanamine1042777-67-2C8H14N2OS
- 1-(3-Ethyl-1,2-oxazol-4-yl)ethan-1-one58752-02-6C7H9NO2
- 1 suppliersMethyl 1,2-oxazole-3-carboxylate25742-68-1C5H5NO3
- 2-Amino-2-(5-methyl-1,2-oxazol-3-yl)acetic acid72699-65-1C6H8N2O3
- N-Methyl-N'-[5-(propan-2-yl)-1,2-oxazol-3-yl]urea55807-51-7C8H13N3O2
- N-(5-tert-Butyl-1,2-oxazol-3-yl)-N,N'-dimethylurea55807-94-8C10H17N3O2
- N,N-Dimethyl-N'-[5-(propan-2-yl)-1,2-oxazol-3-yl]urea55808-32-7C9H15N3O2
- N,N'-Dimethyl-N-[5-(propan-2-yl)-1,2-oxazol-3-yl]urea55807-92-6C9H15N3O2
- N-Butyl-N'-(5-tert-butyl-1,2-oxazol-3-yl)-N-methylurea55808-25-8C13H23N3O2
- N-(5-tert-Butyl-1,2-oxazol-3-yl)-N,N',N'-trimethylurea55809-02-4C11H19N3O2
- 1-Methyl-1-butylthio-3-(5-t-butyl-3-isoxazolyl)urea55809-31-9C13H23N3O2S
- N-Butyl-N-methyl-N'-[5-(propan-2-yl)-1,2-oxazol-3-yl]urea55808-34-9C12H21N3O2
- 4-(2-Chloroethyl)-5-methylisoxazole89415-73-6C6H8ClNO
- 3-Methyl-1,2-oxazole-4-sulfonyl chloride858489-87-9C4H4ClNO3S
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1cn[nH]c1](/scaffold/WTKZEGDFNFYCGP-UHFFFAOYSA-N/structure.svg)
![Scaffold c1c[nH]cn1](/scaffold/RAXXELZNTBOGNW-UHFFFAOYSA-N/structure.svg)
![Scaffold c1cc[nH]c1](/scaffold/KAESVJOAVNADME-UHFFFAOYSA-N/structure.svg)
![Scaffold c1nc[nH]n1](/scaffold/NSPMIYGKQJPBQR-UHFFFAOYSA-N/structure.svg)
