Murcko scaffold
Isoxazole scaffold
5,682 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 5
- Chemicals
- 5,682
- With full pages
- 801
Scaffold SMILES
c1cnoc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1,873 to 1,920 of 5,682 chemicals
3-Isopropyl-5-propylisoxazole-4-carboxylic acid
CAS 1048920-38-2C10H15NO3
5-Butyl-3-isopropylisoxazole-4-carboxylic acid
CAS 1048920-46-2C11H17NO3
5-Ethyl-3-isopropylisoxazole-4-carboxylic acid
CAS 1048920-60-0C9H13NO3
3,5-Dipropylisoxazole-4-carboxylic acid
CAS 1048920-81-5C10H15NO3
N-Butan-2-yl-N'-(5-tert-butyl-1,2-oxazol-3-yl)urea
CAS 55808-70-3C12H21N3O2
Ethyl (isoxazol-3-ylamino)(oxo)acetate
CAS 1001634-98-5C7H8N2O4
3-(3,5-Dimethyl-1,2-oxazol-4-yl)-N-(2,2,2-trifluoroethyl)propanamide
CAS 1207006-95-8C10H13F3N2O2
2-(3,5-Dimethylisoxazol-4-yl)-N-(2,2,2-trifluoroethyl)acetamide
CAS 1207051-20-4C9H11F3N2O2
N1-(3-ethoxypropyl)-N2-(isoxazol-3-yl)oxalamide
CAS 1207049-40-8C10H15N3O4
3,4-Diethyl-5-isoxazolamine hydrochloride
CAS 1185426-22-5C7H13ClN2O
![Methyl[(3-methyl-1,2-oxazol-5-yl)methyl]amine hydrochloride chemical structure, C6H11ClN2O, CAS 1000896-85-4](/s/LPAAQOUQIBYDMQ-UHFFFAOYSA-N.svg)
Methyl[(3-methyl-1,2-oxazol-5-yl)methyl]amine hydrochloride
CAS 1000896-85-4C6H11ClN2O
1-(5-Isopropylisoxazol-3-yl)-N-methylmethanamine
CAS 1160246-01-4C8H14N2O
![2-{[3-(Methylethyl)isoxazol-5-yl]methoxy}ethylamine chemical structure, C9H16N2O2, CAS 1160246-30-9](/s/PRKOJEUDHODQQV-UHFFFAOYSA-N.svg)
2-{[3-(Methylethyl)isoxazol-5-yl]methoxy}ethylamine
CAS 1160246-30-9C9H16N2O2
![Methyl 2-[(3-ethylisoxazol-5-yl)methylthio]acetate chemical structure, C9H13NO3S, CAS 1160246-41-2](/s/YKEBLOXNYKUFJT-UHFFFAOYSA-N.svg)
Methyl 2-[(3-ethylisoxazol-5-yl)methylthio]acetate
CAS 1160246-41-2C9H13NO3S
![[3-(Methylethyl)isoxazol-5-yl]methane-1-thiol chemical structure, C7H11NOS, CAS 1160246-43-4](/s/APZMDJXRIYFLHY-UHFFFAOYSA-N.svg)
[3-(Methylethyl)isoxazol-5-yl]methane-1-thiol
CAS 1160246-43-4C7H11NOS
2-(((3-Isopropylisoxazol-4-yl)methyl)thio)acetic acid
CAS 1160246-44-5C9H13NO3S
1-(3,5-Dimethylisoxazol-4-yl)methanamine hydrochloride
CAS 503469-65-6C6H11ClN2O
((Dimethyl-1,2-oxazol-4-yl)methyl)(methyl)amine hydrochloride
CAS 1177326-01-0C7H13ClN2O
4-Bromo-3,5-(dimethyl-d6)-isoxazole
CAS 1185306-70-0C5H6BrNO
3-Isopropoxyisoxazole-5-carboxylic acid
CAS 1086391-25-4C7H9NO4
1-(3-Ethylisoxazol-5-yl)ethanamine
CAS 1209818-13-2C7H12N2O
(3,5-Dimethylisoxazol-4-yl)methanesulfonyl chloride
CAS 1181458-41-2C6H8ClNO3S
![{[(Dimethyl-1,2-oxazol-4-yl)methyl]sulfanyl}methanimidamide hydrochloride chemical structure, C7H12ClN3OS, CAS 136389-69-0](/s/HVRLCQPOXGURJT-UHFFFAOYSA-N.svg)
{[(Dimethyl-1,2-oxazol-4-yl)methyl]sulfanyl}methanimidamide hydrochloride
CAS 136389-69-0C7H12ClN3OS
1-(5-Methyl-1,2-oxazol-3-yl)-3-(prop-2-yn-1-yl)urea
CAS 1197564-41-2C8H9N3O2
- 3-(5-Chloro-3-methyl-1,2-oxazol-4-yl)propanoic acid1209765-87-6C7H8ClNO3
- (3-Methyl-1,2-oxazol-5-yl)methanamine hydrochloride70183-89-0C5H9ClN2O
- 1-Amino-1-oxopropan-2-yl 5-amino-3-methylisoxazole-4-carboxylate1111604-61-5C8H11N3O4
- 2-(N-Isobutyl-3,5-dimethylisoxazole-4-sulfonamido)acetic acid946505-84-6C11H18N2O5S
- 2-(N-(2-Methoxyethyl)-3,5-dimethylisoxazole-4-sulfonamido)acetic acid1033194-58-9C10H16N2O6S
- tert-Butyl 5-tert-butylisoxazol-3-ylcarbamate89661-71-2C12H20N2O3
- 3-(Boc-amino)-5-tert-butylisoxazole-4-carboxylic acid1065075-72-0C13H20N2O5
- 3-(3,5-Dimethyl-1,2-oxazol-4-yl)propan-1-amine hydrochloride1185449-91-5C8H15ClN2O
- (r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4-yl]propionic Acid Sesquihydrate209977-56-0C18H30N4O15
- 3-Nitroisoxazole-5-carboxamide1224594-00-6C4H3N3O4
- N-Butyl-3-nitro-5-isoxazolecarboxamide1224594-01-7C8H11N3O4
- 4-(Hydroxymethyl)-5-methylisoxazole-3-carboxylic acid1134333-99-5C6H7NO4
- 5-Ethyl-4-(hydroxymethyl)isoxazole-3-carboxylic acid1134334-00-1C7H9NO4
- 3-(Propan-2-yl)-1,2-oxazole-5-carbonitrile1217862-28-6C7H8N2O
- 3-Ethylisoxazole-5-carbonitrile1215295-98-9C6H6N2O
- 2-Chloro-1-(dimethyl-1,2-oxazol-4-yl)ethan-1-one1284455-20-4C7H8ClNO2
- (3-Ethylisoxazol-5-yl)methanamine hydrochloride790254-36-3C6H11ClN2O
- (3-Propyl-1,2-oxazol-5-yl)methanamine hydrochloride1185300-37-1C7H13ClN2O
- 4-Dimethylaminomethyl-5-methyl-isoxazole-3-carboxylic acid hydrobromideC8H13BrN2O3
- 2 suppliersIsoxazole-4-boronic acid1008139-25-0C3H4BNO3
- 2-(3-Ethyl-1,2-oxazol-5-yl)acetic acid1368192-71-5C7H9NO3
- 4-Methyl-5-propyl-1,2-oxazol-3-amine1207175-25-4C7H12N2O
- 1-(5-Methylisoxazol-3-yl)propan-2-amine1207175-74-3C7H12N2O
- 1-(3-Methylisoxazol-5-yl)propan-2-amine1207176-27-9C7H12N2O
Only the first 1,920 are listed here. Use the substructure search to filter further.
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1cn[nH]c1](/scaffold/WTKZEGDFNFYCGP-UHFFFAOYSA-N/structure.svg)
![Scaffold c1c[nH]cn1](/scaffold/RAXXELZNTBOGNW-UHFFFAOYSA-N/structure.svg)
![Scaffold c1cc[nH]c1](/scaffold/KAESVJOAVNADME-UHFFFAOYSA-N/structure.svg)
![Scaffold c1nc[nH]n1](/scaffold/NSPMIYGKQJPBQR-UHFFFAOYSA-N/structure.svg)
