Murcko scaffold
Benzalazine scaffold
140 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 140
- With full pages
- 34
Scaffold SMILES
C(=NN=Cc1ccccc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 140 chemicals
4-Hydroxy-3-methoxybenzaldehyde 2-((4-hydroxy-3-methoxyphenyl)methylene)hydrazone
CAS 1696-60-2C16H16N2O4
![4-(Dimethylamino)benzaldehyde [4-(dimethylamino)benzylidene]hydrazone chemical structure, C18H22N4, CAS 2143-98-8](/s/UPHRISURECPMEH-UHFFFAOYSA-N.svg)
4-(Dimethylamino)benzaldehyde [4-(dimethylamino)benzylidene]hydrazone
CAS 2143-98-8C18H22N4
Syringaldazine
CAS 14414-32-5C18H20N2O6
![N,N'-[Azinobis(methylidyne-4,1-phenylene)]bis(acetamide) chemical structure, C18H18N4O2, CAS 17745-84-5](/s/IJZPLXLJPCGXJX-UHFFFAOYSA-N.svg)
N,N'-[Azinobis(methylidyne-4,1-phenylene)]bis(acetamide)
CAS 17745-84-5C18H18N4O2
Benzalazine
CAS 588-68-1C14H12N2
1-Phenylethanone 2-(1-phenylethylidene)hydrazone
CAS 729-43-1C16H16N2
![1-(2,4-Dichlorophenyl)-N-[(2,4-dichlorophenyl)methylideneamino]methanimine chemical structure, C14H8Cl4N2](/s/VOXSRYYLVMOEEL-UHFFFAOYSA-N.svg)
1-(2,4-Dichlorophenyl)-N-[(2,4-dichlorophenyl)methylideneamino]methanimine
C14H8Cl4N2
![4-[N-[1-(2,4-Dihydroxyphenyl)ethylideneamino]-C-methylcarbonimidoyl]benzene-1,3-diol chemical structure, C16H16N2O4](/s/FKKDSIYPIRBAAP-UHFFFAOYSA-N.svg)
4-[N-[1-(2,4-Dihydroxyphenyl)ethylideneamino]-C-methylcarbonimidoyl]benzene-1,3-diol
C16H16N2O4
RefChem:854849
CAS 3533-45-7C16H16N2O4
![1-Benzylidene-2-[(4-methoxyphenyl)methylidene]hydrazine chemical structure, C15H14N2O, CAS 1149-69-5](/s/IGKAMOVQZRNZIR-UHFFFAOYSA-N.svg)
1-Benzylidene-2-[(4-methoxyphenyl)methylidene]hydrazine
CAS 1149-69-5C15H14N2O
![N,N-Dimethyl-4-{[(1-phenylethylidene)hydrazinylidene]methyl}aniline chemical structure, C17H19N3](/s/TZAMHKUTURYHSL-UHFFFAOYSA-N.svg)
N,N-Dimethyl-4-{[(1-phenylethylidene)hydrazinylidene]methyl}aniline
C17H19N3
![1-(2,4-Dimethoxyphenyl)ethanone 2-[1-(2,4-dimethoxyphenyl)ethylidene]hydrazone chemical structure, C20H24N2O4, CAS 315249-27-5](/s/ALPRNNHLTNJSAQ-UHFFFAOYSA-N.svg)
1-(2,4-Dimethoxyphenyl)ethanone 2-[1-(2,4-dimethoxyphenyl)ethylidene]hydrazone
CAS 315249-27-5C20H24N2O4
![1-(4-Hydroxy-3,5-dimethoxyphenyl)-1-propanone 2-[1-(4-hydroxy-3,5-dimethoxyphenyl)propylidene]hydrazone chemical structure, C22H28N2O6, CAS 117330-16-2](/s/DVVQQGUHFRQXLF-UHFFFAOYSA-N.svg)
1-(4-Hydroxy-3,5-dimethoxyphenyl)-1-propanone 2-[1-(4-hydroxy-3,5-dimethoxyphenyl)propylidene]hydrazone
CAS 117330-16-2C22H28N2O6
![1-(4-Butylphenyl)ethanone 2-[1-(4-butylphenyl)ethylidene]hydrazone chemical structure, C24H32N2, CAS 72928-11-1](/s/IMQCBZMFMQNVMP-UHFFFAOYSA-N.svg)
1-(4-Butylphenyl)ethanone 2-[1-(4-butylphenyl)ethylidene]hydrazone
CAS 72928-11-1C24H32N2
1-(4-Pentylphenyl)ethanone 2-(1-(4-pentylphenyl)ethylidene)hydrazone
CAS 73019-18-8C26H36N2
1,2-Bis(4,5-dimethoxy-2-nitrobenzylidene)hydrazine
CAS 17789-23-0C18H18N4O8
3-Ethoxybenzaldehyde azine
CAS 109692-33-3C18H20N2O2
2-Chloro-4-(dimethylamino)-benzaldehyde azine
CAS 28120-48-1C18H20Cl2N4
2,6-Dichlorobenzaldehyde azine
CAS 32188-71-9C14H8Cl4N2
1,2-Bis(chloro(phenyl)methylene)hydrazine
CAS 729-44-2C14H10Cl2N2
![Bis([C-(2-hydroxyphenyl)-N-[(4-methoxyphenyl)methylideneamino]carbonimidoyl]oxidanium), nickel(2+) chemical structure, C30H30N4NiO6+4](/s/id-5207270.svg)
Bis([C-(2-hydroxyphenyl)-N-[(4-methoxyphenyl)methylideneamino]carbonimidoyl]oxidanium), nickel(2+)
C30H30N4NiO6+4
Benzaldehyde azine
CAS 28867-76-7C14H12N2
Para-tolualdehyde azine
CAS 139030-29-8C16H16N2
(1E,2E)-Bis(2,3-dichlorobenzylidene)hydrazine
CAS 160777-20-8C14H8Cl4N2
- N,N'-Bis-(4-isopropoxy-benzylidene)-hydrazine144103-93-5C20H24N2O2
- N,N-Dimethyl-4-[(E)-[(Z)-1-phenylethylidenehydrazinylidene]methyl]aniline6510-37-8C17H19N3
- 1-(3-Aminophenyl)ethanone [1-(3-aminophenyl)ethylidene]hydrazone315670-87-2C16H18N4
- AE-848/3073503421399-34-8C18H20N2O2
- 1-(4-Fluorophenyl)ethanone [1-(4-fluorophenyl)ethylidene]hydrazone64985-95-1C16H14F2N2
- Butyrophenone, 3-hydroxy-4,4,4-trifluoro-3-trifluoromethyl-, azine101221-66-3C22H16F12N2O2
- 4-[(Z)-[(Z)-[4-(Dimethylamino)phenyl]methylidenehydrazinylidene]methyl]-N,N-dimethylanilineC18H22N4
- 1-{4-Nitrophenyl}ethanone (1-{4-nitrophenyl}ethylidene)hydrazone58896-24-5C16H14N4O4
- (E)-1-(3-Nitrophenyl)-N-[(Z)-(3-nitrophenyl)methylideneamino]methanimineC14H10N4O4
- N,N-Dimethyl-4-[(Z)-((E)-1-phenylethylidenehydrazinylidene)methyl]anilineC17H19N3
- (E)-1-(4-Propan-2-ylphenyl)-N-[(Z)-(4-propan-2-ylphenyl)methylideneamino]methanimine35196-94-2C20H24N2
- (E)-1-(4-Methylphenyl)-N-[(Z)-(4-methylphenyl)methylideneamino]methanimine4702-76-5C16H16N2
- (E)-2-Bromo-N-[(Z)-[2-bromo-1-(4-methylphenyl)ethylidene]amino]-1-(4-methylphenyl)ethanimine63160-09-8C18H18Br2N2
- N-[4-[(Z)-[(Z)-(4-Acetamidophenyl)methylidenehydrazinylidene]methyl]phenyl]acetamideC18H18N4O2
- (Z)-1-(2,6-Dichlorophenyl)-N-[(Z)-(2,6-dichlorophenyl)methylideneamino]methanimineC14H8Cl4N2
- (NE,E)-N-[chloro(phenyl)methylidene]benzenecarbohydrazonoyl chlorideC14H10Cl2N2
- (E)-1-(3,4,5-Trimethoxyphenyl)-N-[(Z)-(3,4,5-trimethoxyphenyl)methylideneamino]methanimine7251-01-6C20H24N2O6
- N'-[(Z)-[Dimethylamino(phenyl)methylidene]amino]-N,N-dimethylbenzenecarboximidamide13724-14-6C18H22N4
- (1Z,2Z)-Bis(2-bromo-1-phenylethylidene)hydrazine35635-90-6C16H14Br2N2
- Ethanone, 1-(3-nitro-4-(pentyloxy)phenyl)-(1-(3-nitro-4-(pentyloxy)phenyl)ethylidene)hydrazone134221-20-8C26H34N4O6
- 3,3'-Difluorobenzaldazine15332-10-2C14H10F2N2
- Benzaldehyde, 4-methoxy-, 2-((4-methoxyphenyl)methylene)hydrazone2299-73-2C16H16N2O2
- 2-Chlorobenzaldehyde azine5328-80-3C14H10Cl2N2
- (1E,2E)-Bis(3-nitrobenzylidene)hydrazine1567-91-5C14H10N4O4
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(COc1ccccc1)Nc1ccccc1476 chemicals
O=C(NN=Cc1ccccc1)c1ccccc1265 chemicals
O=C(C=Cc1ccccc1)Nc1ccccc1175 chemicals
O=C(CCc1ccccc1)Nc1ccccc1153 chemicals
O=C(NCCc1ccccc1)c1ccccc1147 chemicals
S=C(NCc1ccccc1)Nc1ccccc1127 chemicals
O=C(CCNc1ccccc1)c1ccccc1120 chemicals
O=C(NC(=S)Nc1ccccc1)c1ccccc196 chemicals
O=S(=O)(NCCc1ccccc1)c1ccccc183 chemicals
O=C(CNc1ccccc1)Nc1ccccc183 chemicals
O=C(CSc1ccccc1)Nc1ccccc177 chemicals
c1ccc(CCNCc2ccccc2)cc173 chemicals