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Murcko scaffold

Ring system with 2 rings and 20 atoms

33 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
33
With full pages
6
Scaffold SMILES

O=C(CS(=O)(=O)Cc1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CS(=O)(=O)Cc1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

Methyl 4-{[(benzylsulfonyl)acetyl]amino}benzoate chemical structure, C17H17NO5S, CAS 701224-90-0
Methyl 4-{[(benzylsulfonyl)acetyl]amino}benzoate
CAS 701224-90-0C17H17NO5S
2-{[(Benzylsulfonyl)acetyl]amino}benzamide chemical structure, C16H16N2O4S, CAS 701229-61-0
2-{[(Benzylsulfonyl)acetyl]amino}benzamide
CAS 701229-61-0C16H16N2O4S
2-Benzylsulfonyl-N-(2-cyanophenyl)acetamide chemical structure, C16H14N2O3S, CAS 702647-63-0
2-Benzylsulfonyl-N-(2-cyanophenyl)acetamide
CAS 702647-63-0C16H14N2O3S
2-Benzylsulfonyl-N-(2,6-diethylphenyl)acetamide chemical structure, C19H23NO3S, CAS 702649-81-8
2-Benzylsulfonyl-N-(2,6-diethylphenyl)acetamide
CAS 702649-81-8C19H23NO3S
2-Benzylsulfonyl-N-(4-chloro-2,5-dimethoxyphenyl)acetamide chemical structure, C17H18ClNO5S, CAS 701229-84-7
2-Benzylsulfonyl-N-(4-chloro-2,5-dimethoxyphenyl)acetamide
CAS 701229-84-7C17H18ClNO5S
2-Benzylsulfonyl-N-(4-sulfamoylphenyl)acetamide chemical structure, C15H16N2O5S2, CAS 701244-44-2
2-Benzylsulfonyl-N-(4-sulfamoylphenyl)acetamide
CAS 701244-44-2C15H16N2O5S2
2-Benzylsulfonyl-N-(2,5-dichlorophenyl)acetamide chemical structure, C15H13Cl2NO3S, CAS 701227-74-9
2-Benzylsulfonyl-N-(2,5-dichlorophenyl)acetamide
CAS 701227-74-9C15H13Cl2NO3S
2-Benzylsulfonyl-N-(4-bromo-2-fluorophenyl)acetamide chemical structure, C15H13BrFNO3S, CAS 701227-16-9
2-Benzylsulfonyl-N-(4-bromo-2-fluorophenyl)acetamide
CAS 701227-16-9C15H13BrFNO3S
2-Benzylsulfonyl-N-[2-(trifluoromethyl)phenyl]acetamide chemical structure, C16H14F3NO3S, CAS 701229-99-4
2-Benzylsulfonyl-N-[2-(trifluoromethyl)phenyl]acetamide
CAS 701229-99-4C16H14F3NO3S
2-[(4-Chlorophenyl)methanesulfonyl]-N-(4-methoxyphenyl)acetamide chemical structure, C16H16ClNO4S, CAS 339097-72-2
2-[(4-Chlorophenyl)methanesulfonyl]-N-(4-methoxyphenyl)acetamide
CAS 339097-72-2C16H16ClNO4S
2-[(2-Chlorobenzyl)sulfonyl]-N-(2-chlorophenyl)acetamide chemical structure, C15H13Cl2NO3S, CAS 339107-36-7
2-[(2-Chlorobenzyl)sulfonyl]-N-(2-chlorophenyl)acetamide
CAS 339107-36-7C15H13Cl2NO3S
2-[(4-Chlorobenzyl)sulfonyl]-N-methyl-N-phenylacetamide chemical structure, C16H16ClNO3S, CAS 339108-32-6
2-[(4-Chlorobenzyl)sulfonyl]-N-methyl-N-phenylacetamide
CAS 339108-32-6C16H16ClNO3S
2-[(2-Chlorobenzyl)sulfonyl]-N-methyl-N-phenylacetamide chemical structure, C16H16ClNO3S, CAS 339110-03-1
2-[(2-Chlorobenzyl)sulfonyl]-N-methyl-N-phenylacetamide
CAS 339110-03-1C16H16ClNO3S
N-(3-Acetylphenyl)-2-(benzylsulfonyl)acetamide chemical structure, C17H17NO4S, CAS 698987-65-4
N-(3-Acetylphenyl)-2-(benzylsulfonyl)acetamide
CAS 698987-65-4C17H17NO4S
2-(Benzylsulfonyl)-N-(2-methyl-3-nitrophenyl)acetamide chemical structure, C16H16N2O5S, CAS 702647-72-1
2-(Benzylsulfonyl)-N-(2-methyl-3-nitrophenyl)acetamide
CAS 702647-72-1C16H16N2O5S
2-Benzylsulfonyl-N-[2-chloro-5-(trifluoromethyl)phenyl]acetamide chemical structure, C16H13ClF3NO3S, CAS 701238-68-8
2-Benzylsulfonyl-N-[2-chloro-5-(trifluoromethyl)phenyl]acetamide
CAS 701238-68-8C16H13ClF3NO3S
2-Benzylsulfonyl-N-(4-butylphenyl)acetamide chemical structure, C19H23NO3S, CAS 701228-78-6
2-Benzylsulfonyl-N-(4-butylphenyl)acetamide
CAS 701228-78-6C19H23NO3S
2-Benzylsulfonyl-N-(2-methoxy-5-nitrophenyl)acetamide chemical structure, C16H16N2O6S, CAS 702649-56-7
2-Benzylsulfonyl-N-(2-methoxy-5-nitrophenyl)acetamide
CAS 702649-56-7C16H16N2O6S
Dimethyl 5-{[(benzylsulfonyl)acetyl]amino}benzene-1,3-dicarboxylate chemical structure, C19H19NO7S, CAS 702649-22-7
Dimethyl 5-{[(benzylsulfonyl)acetyl]amino}benzene-1,3-dicarboxylate
CAS 702649-22-7C19H19NO7S
2-[(2-Benzylsulfonylacetyl)amino]-N-propan-2-ylbenzamide chemical structure, C19H22N2O4S, CAS 827618-61-1
2-[(2-Benzylsulfonylacetyl)amino]-N-propan-2-ylbenzamide
CAS 827618-61-1C19H22N2O4S
N-(3-Chloro-4-fluorophenyl)-2-(((3,4-dichlorophenyl)methyl)sulfonyl)acetamide chemical structure, C15H11Cl3FNO3S, CAS 218929-48-7
N-(3-Chloro-4-fluorophenyl)-2-(((3,4-dichlorophenyl)methyl)sulfonyl)acetamide
CAS 218929-48-7C15H11Cl3FNO3S
2-Benzylsulfonyl-N-(4-ethoxyphenyl)acetamide chemical structure, C17H19NO4S, CAS 701230-22-0
2-Benzylsulfonyl-N-(4-ethoxyphenyl)acetamide
CAS 701230-22-0C17H19NO4S
2-Benzylsulfonyl-N-[5-(diethylsulfamoyl)-2-methoxyphenyl]acetamide chemical structure, C20H26N2O6S2, CAS 702648-26-8
2-Benzylsulfonyl-N-[5-(diethylsulfamoyl)-2-methoxyphenyl]acetamide
CAS 702648-26-8C20H26N2O6S2
2-Benzylsulfonyl-N-(2-methoxy-4-nitrophenyl)acetamide chemical structure, C16H16N2O6S, CAS 702650-77-9
2-Benzylsulfonyl-N-(2-methoxy-4-nitrophenyl)acetamide
CAS 702650-77-9C16H16N2O6S