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Murcko scaffold

Ring system with 2 rings and 19 atoms

20 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
20
With full pages
7
Scaffold SMILES

O=C(CCC(=O)c1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCC(=O)c1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

Benzenebutanamide, 4-chloro-N-(2-methoxyphenyl)-gamma-oxo- chemical structure, C17H16ClNO3, CAS 64081-82-9
Benzenebutanamide, 4-chloro-N-(2-methoxyphenyl)-gamma-oxo-
CAS 64081-82-9C17H16ClNO3
4-(4-Methoxyphenyl)-4-oxo-n-phenylbutanamide chemical structure, C17H17NO3, CAS 36776-11-1
4-(4-Methoxyphenyl)-4-oxo-n-phenylbutanamide
CAS 36776-11-1C17H17NO3
N-(4-Bromophenyl)-4-oxo-4-phenylbutanamide chemical structure, C16H14BrNO2, CAS 6621-86-9
N-(4-Bromophenyl)-4-oxo-4-phenylbutanamide
CAS 6621-86-9C16H14BrNO2
N-(4-Bromophenyl)-4-(4-ethoxyphenyl)-4-oxobutanamide chemical structure, C18H18BrNO3, CAS 7500-10-9
N-(4-Bromophenyl)-4-(4-ethoxyphenyl)-4-oxobutanamide
CAS 7500-10-9C18H18BrNO3
N-(4-Bromophenyl)-4-(2,5-diethoxyphenyl)-4-oxobutanamide chemical structure, C20H22BrNO4, CAS 7500-11-0
N-(4-Bromophenyl)-4-(2,5-diethoxyphenyl)-4-oxobutanamide
CAS 7500-11-0C20H22BrNO4
4-(4-Oxo-4-phenyl-butyrylamino)-benzoic acid chemical structure, C17H15NO4, CAS 333415-72-8
4-(4-Oxo-4-phenyl-butyrylamino)-benzoic acid
CAS 333415-72-8C17H15NO4
N-(4-Methylphenyl)-4-oxo-4-phenylbutanamide chemical structure, C17H17NO2, CAS 36775-83-4
N-(4-Methylphenyl)-4-oxo-4-phenylbutanamide
CAS 36775-83-4C17H17NO2
N-(4-Ethoxyphenyl)-4-(4-methoxyphenyl)-4-oxobutanamide chemical structure, C19H21NO4, CAS 425652-64-8
N-(4-Ethoxyphenyl)-4-(4-methoxyphenyl)-4-oxobutanamide
CAS 425652-64-8C19H21NO4
4-(4-Methoxyphenyl)-N-(3-methylphenyl)-4-oxobutanamide chemical structure, C18H19NO3, CAS 36776-13-3
4-(4-Methoxyphenyl)-N-(3-methylphenyl)-4-oxobutanamide
CAS 36776-13-3C18H19NO3
N-(3-Chloro-4-methylphenyl)-4-(4-ethoxyphenyl)-4-oxobutanamide chemical structure, C19H20ClNO3, CAS 428447-66-9
N-(3-Chloro-4-methylphenyl)-4-(4-ethoxyphenyl)-4-oxobutanamide
CAS 428447-66-9C19H20ClNO3
4-(4-Methylphenyl)-4-oxo-N-phenylbutanamide chemical structure, C17H17NO2, CAS 36775-95-8
4-(4-Methylphenyl)-4-oxo-N-phenylbutanamide
CAS 36775-95-8C17H17NO2
N-(2,4-Dichlorophenyl)-4-oxo-4-phenylbutanamide chemical structure, C16H13Cl2NO2, CAS 432020-16-1
N-(2,4-Dichlorophenyl)-4-oxo-4-phenylbutanamide
CAS 432020-16-1C16H13Cl2NO2
N-(2,3-Dichlorophenyl)-4-(4-methylphenyl)-4-oxobutanamide chemical structure, C17H15Cl2NO2, CAS 431980-39-1
N-(2,3-Dichlorophenyl)-4-(4-methylphenyl)-4-oxobutanamide
CAS 431980-39-1C17H15Cl2NO2
N-(4-Ethoxyphenyl)-4-(4-fluorophenyl)-4-oxobutanamide chemical structure, C18H18FNO3, CAS 444144-19-8
N-(4-Ethoxyphenyl)-4-(4-fluorophenyl)-4-oxobutanamide
CAS 444144-19-8C18H18FNO3
N-(3-Acetylphenyl)-4-(4-fluorophenyl)-4-oxobutanamide chemical structure, C18H16FNO3, CAS 729577-30-4
N-(3-Acetylphenyl)-4-(4-fluorophenyl)-4-oxobutanamide
CAS 729577-30-4C18H16FNO3
N-(4-Ethylphenyl)-4-oxo-4-phenylbutanamide chemical structure, C18H19NO2, CAS 571154-81-9
N-(4-Ethylphenyl)-4-oxo-4-phenylbutanamide
CAS 571154-81-9C18H19NO2
N-(4-Ethylphenyl)-4-(4-methylphenyl)-4-oxobutanamide chemical structure, C19H21NO2, CAS 731776-43-5
N-(4-Ethylphenyl)-4-(4-methylphenyl)-4-oxobutanamide
CAS 731776-43-5C19H21NO2
N-(4-Chlorophenyl)-4-oxo-4-phenylbutanamide chemical structure, C16H14ClNO2, CAS 38752-55-5
N-(4-Chlorophenyl)-4-oxo-4-phenylbutanamide
CAS 38752-55-5C16H14ClNO2
N-(2-Bromophenyl)-4-fluoro-I(3)-oxobenzenebutanamide chemical structure, C16H13BrFNO2, CAS 1027209-89-7
N-(2-Bromophenyl)-4-fluoro-I(3)-oxobenzenebutanamide
CAS 1027209-89-7C16H13BrFNO2
2-Methoxy-5-methyl-N-(3-methylphenyl)-I(3)-oxobenzenebutanamide chemical structure, C19H21NO3, CAS 1060816-43-4
2-Methoxy-5-methyl-N-(3-methylphenyl)-I(3)-oxobenzenebutanamide
CAS 1060816-43-4C19H21NO3