CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 25 atoms

77 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
77
With full pages
1
Scaffold SMILES

O=C(NCC1CCCOC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC1CCCOC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 77 chemicals

2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(oxan-3-yl)acetic acid chemical structure, C22H23NO5, CAS 1698357-98-0
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(oxan-3-yl)acetic acid
CAS 1698357-98-0C22H23NO5
2-[9H-Fluoren-9-ylmethoxycarbonyl(methyl)amino]-2-(oxan-3-yl)acetic acid chemical structure, C23H25NO5, CAS 1702124-27-3
2-[9H-Fluoren-9-ylmethoxycarbonyl(methyl)amino]-2-(oxan-3-yl)acetic acid
CAS 1702124-27-3C23H25NO5
3-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-tetrahydropyran-3-yl-propanoic acid chemical structure, C23H25NO5, CAS 1696515-48-6
3-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-tetrahydropyran-3-yl-propanoic acid
CAS 1696515-48-6C23H25NO5
(3S)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(oxan-3-yl)propanoic acid chemical structure, C23H25NO5, CAS 1705569-54-5
(3S)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(oxan-3-yl)propanoic acid
CAS 1705569-54-5C23H25NO5
(3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(oxan-3-yl)propanoic acid chemical structure, C23H25NO5, CAS 1705645-91-5
(3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(oxan-3-yl)propanoic acid
CAS 1705645-91-5C23H25NO5
3-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)oxane-3-carboxylic acid chemical structure, C22H23NO5, CAS 2138272-13-4
3-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)oxane-3-carboxylic acid
CAS 2138272-13-4C22H23NO5
2-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}-N-(prop-2-yn-1-yl)formamido)acetic acid chemical structure, C27H28N2O6, CAS 2171857-11-5
2-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}-N-(prop-2-yn-1-yl)formamido)acetic acid
CAS 2171857-11-5C27H28N2O6
2-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}-N-methylformamido)acetic acid chemical structure, C25H28N2O6, CAS 2172395-75-2
2-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}-N-methylformamido)acetic acid
CAS 2172395-75-2C25H28N2O6
(2S)-2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-4-hydroxybutanoic acid chemical structure, C26H30N2O7, CAS 2648919-61-1
(2S)-2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-4-hydroxybutanoic acid
CAS 2648919-61-1C26H30N2O7
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)butanoic acid chemical structure, C26H30N2O6, CAS 2172324-23-9
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)butanoic acid
CAS 2172324-23-9C26H30N2O6
(2S)-2-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}-N-methylformamido)propanoic acid chemical structure, C26H30N2O6, CAS 2648914-67-2
(2S)-2-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}-N-methylformamido)propanoic acid
CAS 2648914-67-2C26H30N2O6
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-2-hydroxypropanoic acid chemical structure, C25H28N2O7, CAS 2172452-32-1
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-2-hydroxypropanoic acid
CAS 2172452-32-1C25H28N2O7
4-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}-N-methylformamido)butanoic acid chemical structure, C27H32N2O6, CAS 2172523-03-2
4-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}-N-methylformamido)butanoic acid
CAS 2172523-03-2C27H32N2O6
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-2,2-dimethylpropanoic acid chemical structure, C27H32N2O6, CAS 2172025-85-1
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-2,2-dimethylpropanoic acid
CAS 2172025-85-1C27H32N2O6
2-(N-Ethyl-1-{3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)acetic acid chemical structure, C26H30N2O6, CAS 2172218-64-1
2-(N-Ethyl-1-{3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)acetic acid
CAS 2172218-64-1C26H30N2O6
(2R)-2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)butanoic acid chemical structure, C26H30N2O6, CAS 2171426-53-0
(2R)-2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)butanoic acid
CAS 2171426-53-0C26H30N2O6
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-2,2-difluoropropanoic acid chemical structure, C25H26F2N2O6, CAS 2172219-24-6
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-2,2-difluoropropanoic acid
CAS 2172219-24-6C25H26F2N2O6
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-3-hydroxybutanoic acid chemical structure, C26H30N2O7, CAS 2171803-05-5
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-3-hydroxybutanoic acid
CAS 2171803-05-5C26H30N2O7
3-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}-N-methylformamido)-2-methylpropanoic acid chemical structure, C27H32N2O6, CAS 2171923-49-0
3-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}-N-methylformamido)-2-methylpropanoic acid
CAS 2171923-49-0C27H32N2O6
(3R)-3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)pentanoic acid chemical structure, C27H32N2O6, CAS 2171414-58-5
(3R)-3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)pentanoic acid
CAS 2171414-58-5C27H32N2O6
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)butanoic acid chemical structure, C26H30N2O6, CAS 2172543-81-4
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)butanoic acid
CAS 2172543-81-4C26H30N2O6
3-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}-N-methylformamido)propanoic acid chemical structure, C26H30N2O6, CAS 2172073-56-0
3-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}-N-methylformamido)propanoic acid
CAS 2172073-56-0C26H30N2O6
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-2-methylpropanoic acid chemical structure, C26H30N2O6, CAS 2171899-06-0
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-2-methylpropanoic acid
CAS 2171899-06-0C26H30N2O6
2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-2-methylpropanoic acid chemical structure, C26H30N2O6, CAS 2171843-72-2
2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)-2-methylpropanoic acid
CAS 2171843-72-2C26H30N2O6