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Murcko scaffold

Ring system with 4 rings and 25 atoms

1,930 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
1,930
With full pages
109
Scaffold SMILES

O=C(NCc1ccccc1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1ccccc1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 1,930 chemicals

5-(4-(9-Fluorenylmethyloxycarbonyl)aminomethyl-3,5-dimethoxyphenoxy)valeric acid chemical structure, C29H31NO7, CAS 115109-65-4
5-(4-(9-Fluorenylmethyloxycarbonyl)aminomethyl-3,5-dimethoxyphenoxy)valeric acid
CAS 115109-65-4C29H31NO7
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(3,4-dichlorophenyl)acetic acid chemical structure, C23H17Cl2NO4, CAS 1260591-04-5
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(3,4-dichlorophenyl)acetic acid
CAS 1260591-04-5C23H17Cl2NO4
Fmoc-(R)-3-amino-3-phenylpropionic acid chemical structure, C24H21NO4, CAS 220498-02-2
Fmoc-(R)-3-amino-3-phenylpropionic acid
CAS 220498-02-2C24H21NO4
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-bromophenyl)propanoic acid chemical structure, C24H20BrNO4, CAS 220497-68-7
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-bromophenyl)propanoic acid
CAS 220497-68-7C24H20BrNO4
Fmoc-4-fluoro-l-phenylglycine chemical structure, C23H18FNO4, CAS 872359-16-5
Fmoc-4-fluoro-l-phenylglycine
CAS 872359-16-5C23H18FNO4
Fmoc-(S)-3-amino-3-(3-nitro-phenyl)-propionic acid chemical structure, C24H20N2O6, CAS 374791-01-2
Fmoc-(S)-3-amino-3-(3-nitro-phenyl)-propionic acid
CAS 374791-01-2C24H20N2O6
3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-(tert-butoxy)phenyl)propanoic acid chemical structure, C28H29NO5, CAS 372144-16-6
3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-(tert-butoxy)phenyl)propanoic acid
CAS 372144-16-6C28H29NO5
3-N-Fmoc-amino-3-(2-T-butoxyphenyl)propionic acid chemical structure, C28H29NO5, CAS 372144-18-8
3-N-Fmoc-amino-3-(2-T-butoxyphenyl)propionic acid
CAS 372144-18-8C28H29NO5
2-(2-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)phenyl)acetic acid chemical structure, C24H21NO4, CAS 882847-15-6
2-(2-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)phenyl)acetic acid
CAS 882847-15-6C24H21NO4
3-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)benzoic acid chemical structure, C23H19NO4, CAS 155369-11-2
3-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)benzoic acid
CAS 155369-11-2C23H19NO4
2-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]phenyl}acetic acid chemical structure, C24H21NO4, CAS 631915-50-9
2-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]phenyl}acetic acid
CAS 631915-50-9C24H21NO4
4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)benzoic acid chemical structure, C23H19NO4, CAS 164470-64-8
4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)benzoic acid
CAS 164470-64-8C23H19NO4
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-phenylacetic acid chemical structure, C23H19NO4, CAS 111524-95-9
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-phenylacetic acid
CAS 111524-95-9C23H19NO4
2-(4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)phenyl)acetic acid chemical structure, C24H21NO4, CAS 176504-01-1
2-(4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)phenyl)acetic acid
CAS 176504-01-1C24H21NO4
Fmoc-N-benzylglycine chemical structure, C24H21NO4, CAS 141743-13-7
Fmoc-N-benzylglycine
CAS 141743-13-7C24H21NO4
3-(4-Bromophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid chemical structure, C24H20BrNO4, CAS 269078-76-4
3-(4-Bromophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
CAS 269078-76-4C24H20BrNO4
3-(4-Cyanophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid chemical structure, C25H20N2O4, CAS 282524-87-2
3-(4-Cyanophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
CAS 282524-87-2C25H20N2O4
3-(2,3-Dichlorophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid chemical structure, C24H19Cl2NO4, CAS 284492-12-2
3-(2,3-Dichlorophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
CAS 284492-12-2C24H19Cl2NO4
3-N-Fmoc-3-(2-fluorophenyl)propionic acid chemical structure, C24H20FNO4, CAS 284492-05-3
3-N-Fmoc-3-(2-fluorophenyl)propionic acid
CAS 284492-05-3C24H20FNO4
3-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(3-fluorophenyl)propanoic acid chemical structure, C24H20FNO4, CAS 284492-07-5
3-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(3-fluorophenyl)propanoic acid
CAS 284492-07-5C24H20FNO4
3-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-fluorophenyl)propanoic acid chemical structure, C24H20FNO4, CAS 188814-36-0
3-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-fluorophenyl)propanoic acid
CAS 188814-36-0C24H20FNO4
3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(propan-2-yl)phenyl)propanoic acid chemical structure, C27H27NO4, CAS 728919-92-4
3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(propan-2-yl)phenyl)propanoic acid
CAS 728919-92-4C27H27NO4
3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-methoxyphenyl)propanoic acid chemical structure, C25H23NO5, CAS 284492-01-9
3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-methoxyphenyl)propanoic acid
CAS 284492-01-9C25H23NO5
3-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-methoxyphenyl)propanoic acid chemical structure, C25H23NO5, CAS 284492-02-0
3-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-methoxyphenyl)propanoic acid
CAS 284492-02-0C25H23NO5