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Murcko scaffold

Ring system with 2 rings and 18 atoms

23 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
23
With full pages
5
Scaffold SMILES

O=C(NCCCc1ccccc1)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCCc1ccccc1)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

5-Bromo-N-(3-phenylpropyl)pyridine-3-carboxamide chemical structure, C15H15BrN2O, CAS 851209-81-9
5-Bromo-N-(3-phenylpropyl)pyridine-3-carboxamide
CAS 851209-81-9C15H15BrN2O
5,6-Dichloro-N-(4-phenylbutan-2-yl)pyridine-3-carboxamide chemical structure, C16H16Cl2N2O, CAS 854354-73-7
5,6-Dichloro-N-(4-phenylbutan-2-yl)pyridine-3-carboxamide
CAS 854354-73-7C16H16Cl2N2O
2-Ethoxy-N-(4-phenylbutan-2-yl)pyridine-3-carboxamide chemical structure, C18H22N2O2, CAS 847783-24-8
2-Ethoxy-N-(4-phenylbutan-2-yl)pyridine-3-carboxamide
CAS 847783-24-8C18H22N2O2
2-(Methylsulfanyl)-N-(4-phenylbutan-2-yl)pyridine-3-carboxamide chemical structure, C17H20N2OS, CAS 794537-27-2
2-(Methylsulfanyl)-N-(4-phenylbutan-2-yl)pyridine-3-carboxamide
CAS 794537-27-2C17H20N2OS
6-Chloro-N-(4-phenylbutan-2-yl)pyridine-3-carboxamide chemical structure, C16H17ClN2O, CAS 794559-74-3
6-Chloro-N-(4-phenylbutan-2-yl)pyridine-3-carboxamide
CAS 794559-74-3C16H17ClN2O
5,6-Dichloro-N-[3-(2,4-dimethylphenyl)propyl]pyridine-3-carboxamide chemical structure, C17H18Cl2N2O, CAS 869630-38-6
5,6-Dichloro-N-[3-(2,4-dimethylphenyl)propyl]pyridine-3-carboxamide
CAS 869630-38-6C17H18Cl2N2O
2-Chloro-N-[3-(2,4-dimethylphenyl)propyl]pyridine-3-carboxamide chemical structure, C17H19ClN2O, CAS 1110860-52-0
2-Chloro-N-[3-(2,4-dimethylphenyl)propyl]pyridine-3-carboxamide
CAS 1110860-52-0C17H19ClN2O
N-{3-[4-(Dimethylamino)phenyl]propyl}-2-(methylsulfanyl)pyridine-3-carboxamide chemical structure, C18H23N3OS, CAS 1147696-58-9
N-{3-[4-(Dimethylamino)phenyl]propyl}-2-(methylsulfanyl)pyridine-3-carboxamide
CAS 1147696-58-9C18H23N3OS
2-Amino-N-(3-phenylpropyl)pyridine-3-carboxamide chemical structure, C15H17N3O, CAS 1271647-51-8
2-Amino-N-(3-phenylpropyl)pyridine-3-carboxamide
CAS 1271647-51-8C15H17N3O
2-Amino-N-(4-phenylbutan-2-yl)pyridine-3-carboxamide chemical structure, C16H19N3O, CAS 1326807-77-5
2-Amino-N-(4-phenylbutan-2-yl)pyridine-3-carboxamide
CAS 1326807-77-5C16H19N3O
Methyl 3-[(2-chloropyridin-3-yl)formamido]-2-[(4-hydroxyphenyl)methyl]propanoate chemical structure, C17H17ClN2O4, CAS 1311717-31-3
Methyl 3-[(2-chloropyridin-3-yl)formamido]-2-[(4-hydroxyphenyl)methyl]propanoate
CAS 1311717-31-3C17H17ClN2O4
N-(1-Cyano-1-methyl-3-phenylpropyl)-6-methylpyridine-3-carboxamide chemical structure, C18H19N3O, CAS 1355917-45-1
N-(1-Cyano-1-methyl-3-phenylpropyl)-6-methylpyridine-3-carboxamide
CAS 1355917-45-1C18H19N3O
5-Bromo-2-chloro-N-(4-methyl-4-phenylpentan-2-yl)pyridine-3-carboxamide chemical structure, C18H20BrClN2O, CAS 1365632-21-8
5-Bromo-2-chloro-N-(4-methyl-4-phenylpentan-2-yl)pyridine-3-carboxamide
CAS 1365632-21-8C18H20BrClN2O
6-Fluoro-N-(3-phenylpropyl)pyridine-3-carboxamide chemical structure, C15H15FN2O, CAS 1376301-97-1
6-Fluoro-N-(3-phenylpropyl)pyridine-3-carboxamide
CAS 1376301-97-1C15H15FN2O
N-(2-Hydroxy-3-(4-methoxyphenyl)-2-methylpropyl)-2-(methylthio)nicotinamide chemical structure, C18H22N2O3S, CAS 1396745-94-0
N-(2-Hydroxy-3-(4-methoxyphenyl)-2-methylpropyl)-2-(methylthio)nicotinamide
CAS 1396745-94-0C18H22N2O3S
2-Bromo-N-{4-[4-(propan-2-yloxy)phenyl]butan-2-yl}pyridine-3-carboxamide chemical structure, C19H23BrN2O2, CAS 1445105-07-6
2-Bromo-N-{4-[4-(propan-2-yloxy)phenyl]butan-2-yl}pyridine-3-carboxamide
CAS 1445105-07-6C19H23BrN2O2
6-Chloro-N-{2-[(2,5-difluorophenyl)methyl]-3-hydroxypropyl}pyridine-3-carboxamide chemical structure, C16H15ClF2N2O2, CAS 1797245-67-0
6-Chloro-N-{2-[(2,5-difluorophenyl)methyl]-3-hydroxypropyl}pyridine-3-carboxamide
CAS 1797245-67-0C16H15ClF2N2O2
5-Bromo-N-(2-hydroxy-3-(4-methoxyphenyl)-2-methylpropyl)nicotinamide chemical structure, C17H19BrN2O3, CAS 1798488-74-0
5-Bromo-N-(2-hydroxy-3-(4-methoxyphenyl)-2-methylpropyl)nicotinamide
CAS 1798488-74-0C17H19BrN2O3
2-Chloro-N-[4-(4-methoxyphenyl)butan-2-yl]-5-(trifluoromethyl)pyridine-3-carboxamide chemical structure, C18H18ClF3N2O2, CAS 1795344-71-6
2-Chloro-N-[4-(4-methoxyphenyl)butan-2-yl]-5-(trifluoromethyl)pyridine-3-carboxamide
CAS 1795344-71-6C18H18ClF3N2O2
5-Bromo-N-(3-(3-chlorophenyl)-3-hydroxypropyl)nicotinamide chemical structure, C15H14BrClN2O2, CAS 2034520-94-8
5-Bromo-N-(3-(3-chlorophenyl)-3-hydroxypropyl)nicotinamide
CAS 2034520-94-8C15H14BrClN2O2
N-(3-(3-Chlorophenyl)-3-hydroxypropyl)-6-(trifluoromethyl)nicotinamide chemical structure, C16H14ClF3N2O2, CAS 2034456-80-7
N-(3-(3-Chlorophenyl)-3-hydroxypropyl)-6-(trifluoromethyl)nicotinamide
CAS 2034456-80-7C16H14ClF3N2O2
5-Chloro-N-(3-phenylpropyl)nicotinamide chemical structure, C15H15ClN2O, CAS 2875176-59-1
5-Chloro-N-(3-phenylpropyl)nicotinamide
CAS 2875176-59-1C15H15ClN2O
5-Fluoro-N-(3-phenylpropyl)nicotinamide chemical structure, C15H15FN2O, CAS 2945311-60-2
5-Fluoro-N-(3-phenylpropyl)nicotinamide
CAS 2945311-60-2C15H15FN2O