CompoundList
Sign in
Murcko scaffold

1-(2,3-Dihydro-1,4-benzodioxine-6-sulfonyl)piperazine scaffold

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
6
With full pages
5
Scaffold SMILES

O=S(=O)(c1ccc2c(c1)OCCO2)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(2,3-Dihydro-1,4-benzodioxine-6-sulfonyl)piperazine page
Murcko scaffold O=S(=O)(c1ccc2c(c1)OCCO2)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

1-(2,3-Dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-methylpiperazine chemical structure, C13H18N2O4S, CAS 305853-89-8
1-(2,3-Dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-methylpiperazine
CAS 305853-89-8C13H18N2O4S
Ethyl 4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine-1-carboxylate chemical structure, C15H20N2O6S, CAS 333441-41-1
Ethyl 4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine-1-carboxylate
CAS 333441-41-1C15H20N2O6S
1-(2,3-Dihydro-1,4-benzodioxine-6-sulfonyl)piperazine chemical structure, C12H16N2O4S, CAS 95591-73-4
1-(2,3-Dihydro-1,4-benzodioxine-6-sulfonyl)piperazine
CAS 95591-73-4C12H16N2O4S
2-Chloro-1-[4-(2,3-dihydro-1,4-benzodioxine-6-sulfonyl)piperazin-1-yl]ethan-1-one chemical structure, C14H17ClN2O5S, CAS 722491-28-3
2-Chloro-1-[4-(2,3-dihydro-1,4-benzodioxine-6-sulfonyl)piperazin-1-yl]ethan-1-one
CAS 722491-28-3C14H17ClN2O5S
1-(2,3-Dihydro-1,4-benzodioxine-6-sulfonyl)piperazine hydrochloride chemical structure, C12H17ClN2O4S, CAS 95591-80-3
1-(2,3-Dihydro-1,4-benzodioxine-6-sulfonyl)piperazine hydrochloride
CAS 95591-80-3C12H17ClN2O4S
1-(2,3-Dihydro-benzo[1,4]dioxine-6-sulfonyl)-4-ethanesulfonyl-piperazine chemical structure, C14H20N2O6S2, CAS 606133-91-9
1-(2,3-Dihydro-benzo[1,4]dioxine-6-sulfonyl)-4-ethanesulfonyl-piperazine
CAS 606133-91-9C14H20N2O6S2