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Murcko scaffold

Ring system with 4 rings and 24 atoms

15 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
15
With full pages
2
Scaffold SMILES

O=c1oc2c(CN3CCCCC3)cccc2cc1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1oc2c(CN3CCCCC3)cccc2cc1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

7-Hydroxy-3-(4-methoxyphenyl)-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C22H23NO4, CAS 825657-85-0
7-Hydroxy-3-(4-methoxyphenyl)-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 825657-85-0C22H23NO4
3-(3,4-Dimethoxyphenyl)-7-hydroxy-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C23H25NO5, CAS 869081-09-4
3-(3,4-Dimethoxyphenyl)-7-hydroxy-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 869081-09-4C23H25NO5
7-Hydroxy-3-phenyl-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C21H21NO3, CAS 887217-58-5
7-Hydroxy-3-phenyl-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 887217-58-5C21H21NO3
7-Hydroxy-3-(4-methoxyphenyl)-8-[(4-methylpiperidin-1-yl)methyl]-2H-chromen-2-one chemical structure, C23H25NO4, CAS 869340-61-4
7-Hydroxy-3-(4-methoxyphenyl)-8-[(4-methylpiperidin-1-yl)methyl]-2H-chromen-2-one
CAS 869340-61-4C23H25NO4
3-(2,4-Dimethoxyphenyl)-7-hydroxy-8-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one chemical structure, C24H27NO5, CAS 859669-52-6
3-(2,4-Dimethoxyphenyl)-7-hydroxy-8-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one
CAS 859669-52-6C24H27NO5
3-(2,4-Dimethoxyphenyl)-7-hydroxy-8-((2-methylpiperidin-1-yl)methyl)-2H-chromen-2-one chemical structure, C24H27NO5, CAS 859668-53-4
3-(2,4-Dimethoxyphenyl)-7-hydroxy-8-((2-methylpiperidin-1-yl)methyl)-2H-chromen-2-one
CAS 859668-53-4C24H27NO5
3-(2,4-Dimethoxyphenyl)-7-hydroxy-8-[(3-methylpiperidin-1-yl)methyl]-2H-chromen-2-one chemical structure, C24H27NO5, CAS 859670-46-5
3-(2,4-Dimethoxyphenyl)-7-hydroxy-8-[(3-methylpiperidin-1-yl)methyl]-2H-chromen-2-one
CAS 859670-46-5C24H27NO5
3-(2,5-Dimethoxyphenyl)-7-hydroxy-8-((3-methylpiperidin-1-yl)methyl)-2H-chromen-2-one chemical structure, C24H27NO5, CAS 859670-74-9
3-(2,5-Dimethoxyphenyl)-7-hydroxy-8-((3-methylpiperidin-1-yl)methyl)-2H-chromen-2-one
CAS 859670-74-9C24H27NO5
3-(2,5-Dimethoxyphenyl)-7-hydroxy-8-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one chemical structure, C24H27NO5, CAS 864818-97-3
3-(2,5-Dimethoxyphenyl)-7-hydroxy-8-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one
CAS 864818-97-3C24H27NO5
3-(2,5-Dimethoxyphenyl)-7-hydroxy-4-methyl-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C24H27NO5, CAS 864819-01-2
3-(2,5-Dimethoxyphenyl)-7-hydroxy-4-methyl-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 864819-01-2C24H27NO5
3-(2,5-Dimethoxyphenyl)-7-hydroxy-8-((2-methylpiperidin-1-yl)methyl)-2H-chromen-2-one chemical structure, C24H27NO5, CAS 864818-79-1
3-(2,5-Dimethoxyphenyl)-7-hydroxy-8-((2-methylpiperidin-1-yl)methyl)-2H-chromen-2-one
CAS 864818-79-1C24H27NO5
7-Hydroxy-4-methyl-3-phenyl-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C22H23NO3, CAS 869081-07-2
7-Hydroxy-4-methyl-3-phenyl-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 869081-07-2C22H23NO3
7-Hydroxy-3-(4-methoxyphenyl)-8-[(3-methylpiperidin-1-yl)methyl]-2H-chromen-2-one chemical structure, C23H25NO4, CAS 869340-58-9
7-Hydroxy-3-(4-methoxyphenyl)-8-[(3-methylpiperidin-1-yl)methyl]-2H-chromen-2-one
CAS 869340-58-9C23H25NO4
7-Hydroxy-3-(3-methoxyphenyl)-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C22H23NO4, CAS 951996-57-9
7-Hydroxy-3-(3-methoxyphenyl)-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 951996-57-9C22H23NO4
4,7-Dihydroxy-3-(2-methoxyphenyl)-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C22H23NO5, CAS 929835-33-6
4,7-Dihydroxy-3-(2-methoxyphenyl)-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 929835-33-6C22H23NO5