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Murcko scaffold

Ring system with 4 rings and 24 atoms

19 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
19
With full pages
13
Scaffold SMILES

O=c1c(-c2ccccc2)coc2c(CN3CCOCC3)cccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(-c2ccccc2)coc2c(CN3CCOCC3)cccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

3-(4-Chlorophenyl)-7-hydroxy-8-(4-morpholinylmethyl)-4H-chromen-4-one chemical structure, C20H18ClNO4, CAS 302575-36-6
3-(4-Chlorophenyl)-7-hydroxy-8-(4-morpholinylmethyl)-4H-chromen-4-one
CAS 302575-36-6C20H18ClNO4
7-Hydroxy-3-(2-methoxyphenyl)-8-(morpholin-4-ylmethyl)-2-(trifluoromethyl)chromen-4-one chemical structure, C22H20F3NO5, CAS 303119-42-8
7-Hydroxy-3-(2-methoxyphenyl)-8-(morpholin-4-ylmethyl)-2-(trifluoromethyl)chromen-4-one
CAS 303119-42-8C22H20F3NO5
7-Hydroxy-3-(2-methoxy-phenyl)-8-morpholin-4-ylmethyl-chromen-4-one chemical structure, C21H21NO5, CAS 6152-13-2
7-Hydroxy-3-(2-methoxy-phenyl)-8-morpholin-4-ylmethyl-chromen-4-one
CAS 6152-13-2C21H21NO5
Isoflavone, 7-hydroxy-2-methyl-8-(morpholinomethyl)-, hydrochloride chemical structure, C21H22ClNO4, CAS 67292-73-3
Isoflavone, 7-hydroxy-2-methyl-8-(morpholinomethyl)-, hydrochloride
CAS 67292-73-3C21H22ClNO4
7-Hydroxy-2-methyl-8-(morpholin-4-ylmethyl)-3-phenylchromen-4-one chemical structure, C21H21NO4, CAS 111978-67-7
7-Hydroxy-2-methyl-8-(morpholin-4-ylmethyl)-3-phenylchromen-4-one
CAS 111978-67-7C21H21NO4
Isoflavone, 7-hydroxy-8-(morpholinomethyl)-, hydrochloride chemical structure, C20H20ClNO4, CAS 67292-75-5
Isoflavone, 7-hydroxy-8-(morpholinomethyl)-, hydrochloride
CAS 67292-75-5C20H20ClNO4
3-(4-Bromophenyl)-7-hydroxy-8-(morpholin-4-ylmethyl)chromen-4-one chemical structure, C20H18BrNO4, CAS 847367-00-4
3-(4-Bromophenyl)-7-hydroxy-8-(morpholin-4-ylmethyl)chromen-4-one
CAS 847367-00-4C20H18BrNO4
3-(4-Bromophenyl)-7-hydroxy-2-methyl-8-(morpholin-4-ylmethyl)chromen-4-one chemical structure, C21H20BrNO4, CAS 847858-16-6
3-(4-Bromophenyl)-7-hydroxy-2-methyl-8-(morpholin-4-ylmethyl)chromen-4-one
CAS 847858-16-6C21H20BrNO4
3-(3,4-Dimethoxyphenyl)-7-hydroxy-8-(morpholin-4-ylmethyl)-2-(trifluoromethyl)chromen-4-one chemical structure, C23H22F3NO6, CAS 307535-04-2
3-(3,4-Dimethoxyphenyl)-7-hydroxy-8-(morpholin-4-ylmethyl)-2-(trifluoromethyl)chromen-4-one
CAS 307535-04-2C23H22F3NO6
3-(4-Chlorophenyl)-7-hydroxy-8-(morpholinomethyl)-2-(trifluoromethyl)-4H-chromen-4-one chemical structure, C21H17ClF3NO4, CAS 307507-07-9
3-(4-Chlorophenyl)-7-hydroxy-8-(morpholinomethyl)-2-(trifluoromethyl)-4H-chromen-4-one
CAS 307507-07-9C21H17ClF3NO4
3-(3,4-Dimethoxyphenyl)-8-[(2,6-dimethylmorpholin-4-yl)methyl]-7-hydroxy-2-(trifluoromethyl)-4H-chromen-4-one chemical structure, C25H26F3NO6, CAS 307535-10-0
3-(3,4-Dimethoxyphenyl)-8-[(2,6-dimethylmorpholin-4-yl)methyl]-7-hydroxy-2-(trifluoromethyl)-4H-chromen-4-one
CAS 307535-10-0C25H26F3NO6
8-[(2,6-Dimethylmorpholin-4-yl)methyl]-7-hydroxy-3-phenylchromen-4-one chemical structure, C22H23NO4, CAS 433690-76-7
8-[(2,6-Dimethylmorpholin-4-yl)methyl]-7-hydroxy-3-phenylchromen-4-one
CAS 433690-76-7C22H23NO4
3-(4-Bromophenyl)-7-hydroxy-8-(morpholin-4-ylmethyl)-2-(trifluoromethyl)chromen-4-one chemical structure, C21H17BrF3NO4, CAS 847858-57-5
3-(4-Bromophenyl)-7-hydroxy-8-(morpholin-4-ylmethyl)-2-(trifluoromethyl)chromen-4-one
CAS 847858-57-5C21H17BrF3NO4
3-(4-Chlorophenyl)-7-hydroxy-2-methyl-8-(morpholin-4-ylmethyl)chromen-4-one chemical structure, C21H20ClNO4, CAS 844829-08-9
3-(4-Chlorophenyl)-7-hydroxy-2-methyl-8-(morpholin-4-ylmethyl)chromen-4-one
CAS 844829-08-9C21H20ClNO4
3-(3,4-Dimethoxyphenyl)-7-hydroxy-2-methyl-8-(morpholin-4-ylmethyl)chromen-4-one chemical structure, C23H25NO6, CAS 844463-54-3
3-(3,4-Dimethoxyphenyl)-7-hydroxy-2-methyl-8-(morpholin-4-ylmethyl)chromen-4-one
CAS 844463-54-3C23H25NO6
7-Hydroxy-3-(4-methoxyphenyl)-2-methyl-8-(morpholin-4-ylmethyl)chromen-4-one chemical structure, C22H23NO5, CAS 847179-76-4
7-Hydroxy-3-(4-methoxyphenyl)-2-methyl-8-(morpholin-4-ylmethyl)chromen-4-one
CAS 847179-76-4C22H23NO5
7-Hydroxy-3-(4-methoxyphenyl)-8-(morpholin-4-ylmethyl)chromen-4-one chemical structure, C21H21NO5, CAS 845635-80-5
7-Hydroxy-3-(4-methoxyphenyl)-8-(morpholin-4-ylmethyl)chromen-4-one
CAS 845635-80-5C21H21NO5
7-Hydroxy-3-(4-methoxyphenyl)-8-(morpholin-4-ylmethyl)-2-(trifluoromethyl)chromen-4-one chemical structure, C22H20F3NO5, CAS 848279-08-3
7-Hydroxy-3-(4-methoxyphenyl)-8-(morpholin-4-ylmethyl)-2-(trifluoromethyl)chromen-4-one
CAS 848279-08-3C22H20F3NO5
7-Hydroxy-3-(2-methoxyphenyl)-2-methyl-8-(morpholin-4-ylmethyl)chromen-4-one chemical structure, C22H23NO5, CAS 848205-26-5
7-Hydroxy-3-(2-methoxyphenyl)-2-methyl-8-(morpholin-4-ylmethyl)chromen-4-one
CAS 848205-26-5C22H23NO5