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Murcko scaffold

Acetamide, N-phenyl-2-((1-phenyl-5-(4-pyridinyl)-1H-1,3,4-triazol-2-yl)thio)- scaffold

209 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
209
With full pages
88
Scaffold SMILES

O=C(CSc1nnc(-c2ccncc2)n1-c1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Acetamide, N-phenyl-2-((1-phenyl-5-(4-pyridinyl)-1H-1,3,4-triazol-2-yl)thio)- page
Murcko scaffold O=C(CSc1nnc(-c2ccncc2)n1-c1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 209 chemicals

N-(2,4-Dimethylphenyl)-2-((4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C23H21N5OS, CAS 332376-60-0
N-(2,4-Dimethylphenyl)-2-((4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 332376-60-0C23H21N5OS
Ethyl 4-[({[4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetyl)amino]benzoate chemical structure, C24H21N5O3S, CAS 338425-12-0
Ethyl 4-[({[4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetyl)amino]benzoate
CAS 338425-12-0C24H21N5O3S
N-(2-Bromo-4-methylphenyl)-2-{[4-(4-methylphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C23H20BrN5OS, CAS 477318-68-6
N-(2-Bromo-4-methylphenyl)-2-{[4-(4-methylphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 477318-68-6C23H20BrN5OS
N-(4-Methoxyphenyl)-2-{[4-(4-methylphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C23H21N5O2S, CAS 482640-29-9
N-(4-Methoxyphenyl)-2-{[4-(4-methylphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 482640-29-9C23H21N5O2S
N-(4-Ethoxyphenyl)-2-{[4-(4-methylphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C24H23N5O2S, CAS 482640-30-2
N-(4-Ethoxyphenyl)-2-{[4-(4-methylphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 482640-30-2C24H23N5O2S
2-[[4-(4-Methylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide chemical structure, C23H18F3N5OS, CAS 482640-33-5
2-[[4-(4-Methylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide
CAS 482640-33-5C23H18F3N5OS
N-(2-Ethyl-6-methylphenyl)-2-[[4-(4-methylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C25H25N5OS, CAS 482640-39-1
N-(2-Ethyl-6-methylphenyl)-2-[[4-(4-methylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 482640-39-1C25H25N5OS
2-[[4-(4-Ethylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-N-(3-methoxyphenyl)acetamide chemical structure, C24H23N5O2S, CAS 663212-59-7
2-[[4-(4-Ethylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-N-(3-methoxyphenyl)acetamide
CAS 663212-59-7C24H23N5O2S
N-(4-Bromo-2,6-dimethylphenyl)-2-[[4-(3-methylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C24H22BrN5OS, CAS 5833-40-9
N-(4-Bromo-2,6-dimethylphenyl)-2-[[4-(3-methylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 5833-40-9C24H22BrN5OS
N-(4-Bromo-2-chlorophenyl)-2-[[4-(4-ethylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C23H19BrClN5OS, CAS 663214-13-9
N-(4-Bromo-2-chlorophenyl)-2-[[4-(4-ethylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 663214-13-9C23H19BrClN5OS
N-(4-Bromo-2-fluorophenyl)-2-[[4-(4-ethylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C23H19BrFN5OS, CAS 663214-14-0
N-(4-Bromo-2-fluorophenyl)-2-[[4-(4-ethylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 663214-14-0C23H19BrFN5OS
2-[[4-(4-Fluorophenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide chemical structure, C22H15F4N5OS, CAS 333792-17-9
2-[[4-(4-Fluorophenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide
CAS 333792-17-9C22H15F4N5OS
2-[[4-(4-Ethoxyphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide chemical structure, C24H20F3N5O2S, CAS 664314-05-0
2-[[4-(4-Ethoxyphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide
CAS 664314-05-0C24H20F3N5O2S
N-(3-Bromophenyl)-2-[(4-phenyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C21H16BrN5OS, CAS 354545-41-8
N-(3-Bromophenyl)-2-[(4-phenyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide
CAS 354545-41-8C21H16BrN5OS
Acetamide, N-(4-methoxyphenyl)-2-((4-phenyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)- chemical structure, C22H19N5O2S, CAS 113518-49-3
Acetamide, N-(4-methoxyphenyl)-2-((4-phenyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-
CAS 113518-49-3C22H19N5O2S
2-{[4-(4-Chlorophenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(2-methylphenyl)acetamide chemical structure, C22H18ClN5OS, CAS 476484-03-4
2-{[4-(4-Chlorophenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(2-methylphenyl)acetamide
CAS 476484-03-4C22H18ClN5OS
2-{[4-(4-Chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(2-fluorophenyl)acetamide chemical structure, C21H15ClFN5OS, CAS 613225-85-7
2-{[4-(4-Chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(2-fluorophenyl)acetamide
CAS 613225-85-7C21H15ClFN5OS
N-(2,5-Dimethylphenyl)-2-[[4-(4-methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]acetamide chemical structure, C24H23N5O2S, CAS 626209-19-6
N-(2,5-Dimethylphenyl)-2-[[4-(4-methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]acetamide
CAS 626209-19-6C24H23N5O2S
N-(3-Methoxyphenyl)-2-[[4-(4-methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]acetamide chemical structure, C23H21N5O3S, CAS 626209-24-3
N-(3-Methoxyphenyl)-2-[[4-(4-methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]acetamide
CAS 626209-24-3C23H21N5O3S
2-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-N-(4-methylphenyl)acetamide chemical structure, C23H21N5O2S, CAS 626209-29-8
2-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-N-(4-methylphenyl)acetamide
CAS 626209-29-8C23H21N5O2S
N-(2-Fluorophenyl)-2-[[4-(4-methoxyphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C22H18FN5O2S, CAS 626209-38-9
N-(2-Fluorophenyl)-2-[[4-(4-methoxyphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 626209-38-9C22H18FN5O2S
N-(4-Chlorophenyl)-2-((1-phenyl-5-(4-pyridinyl)-1H-1,3,4-triazol-2-yl)thio)acetamide chemical structure, C21H16ClN5OS, CAS 113518-50-6
N-(4-Chlorophenyl)-2-((1-phenyl-5-(4-pyridinyl)-1H-1,3,4-triazol-2-yl)thio)acetamide
CAS 113518-50-6C21H16ClN5OS
Acetamide, N-(2-methylphenyl)-2-((4-phenyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)- chemical structure, C22H19N5OS, CAS 113518-47-1
Acetamide, N-(2-methylphenyl)-2-((4-phenyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-
CAS 113518-47-1C22H19N5OS
Acetamide, N-(3-nitrophenyl)-2-((1-phenyl-5-(4-pyridinyl)-1H-1,3,4-triazol-2-yl)thio)- chemical structure, C21H16N6O3S, CAS 113518-52-8
Acetamide, N-(3-nitrophenyl)-2-((1-phenyl-5-(4-pyridinyl)-1H-1,3,4-triazol-2-yl)thio)-
CAS 113518-52-8C21H16N6O3S