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Murcko scaffold

Ring system with 3 rings and 19 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
18
With full pages
8
Scaffold SMILES

O=C1C=C(N2CCOCC2)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=C(N2CCOCC2)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

3-Chloro-1-(2,4-dimethylphenyl)-4-morpholin-4-ylpyrrole-2,5-dione chemical structure, C16H17ClN2O3, CAS 307528-24-1
3-Chloro-1-(2,4-dimethylphenyl)-4-morpholin-4-ylpyrrole-2,5-dione
CAS 307528-24-1C16H17ClN2O3
3-Chloro-4-morpholin-4-yl-1-phenyl-pyrrole-2,5-dione chemical structure, C14H13ClN2O3, CAS 5359-65-9
3-Chloro-4-morpholin-4-yl-1-phenyl-pyrrole-2,5-dione
CAS 5359-65-9C14H13ClN2O3
3-Chloro-1-(3-chloro-4-methylphenyl)-4-morpholin-4-ylpyrrole-2,5-dione chemical structure, C15H14Cl2N2O3, CAS 307534-32-3
3-Chloro-1-(3-chloro-4-methylphenyl)-4-morpholin-4-ylpyrrole-2,5-dione
CAS 307534-32-3C15H14Cl2N2O3
3-Chloro-1-(2-fluorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione chemical structure, C14H12ClFN2O3, CAS 685849-29-0
3-Chloro-1-(2-fluorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione
CAS 685849-29-0C14H12ClFN2O3
3-Chloro-4-morpholin-4-yl-1-(4-propan-2-ylphenyl)pyrrole-2,5-dione chemical structure, C17H19ClN2O3, CAS 692742-91-9
3-Chloro-4-morpholin-4-yl-1-(4-propan-2-ylphenyl)pyrrole-2,5-dione
CAS 692742-91-9C17H19ClN2O3
3-Chloro-1-(2,5-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione chemical structure, C14H11Cl3N2O3, CAS 307534-51-6
3-Chloro-1-(2,5-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione
CAS 307534-51-6C14H11Cl3N2O3
3-Chloro-1-(4-iodophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione chemical structure, C14H12ClIN2O3, CAS 370854-62-9
3-Chloro-1-(4-iodophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione
CAS 370854-62-9C14H12ClIN2O3
3-Chloro-1-(2,3-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione chemical structure, C14H11Cl3N2O3, CAS 307527-74-8
3-Chloro-1-(2,3-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione
CAS 307527-74-8C14H11Cl3N2O3
3-Chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione chemical structure, C14H11Cl3N2O3, CAS 415713-60-9
3-Chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione
CAS 415713-60-9C14H11Cl3N2O3
Methyl 4-(3-chloro-4-morpholino-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate chemical structure, C16H15ClN2O5, CAS 685135-21-1
Methyl 4-(3-chloro-4-morpholino-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate
CAS 685135-21-1C16H15ClN2O5
1-(4-Bromophenyl)-3-chloro-4-morpholin-4-ylpyrrole-2,5-dione chemical structure, C14H12BrClN2O3, CAS 5346-06-5
1-(4-Bromophenyl)-3-chloro-4-morpholin-4-ylpyrrole-2,5-dione
CAS 5346-06-5C14H12BrClN2O3
1-(4-Ethylphenyl)-3-(morpholin-4-yl)-1H-pyrrole-2,5-dione chemical structure, C16H18N2O3, CAS 726200-79-9
1-(4-Ethylphenyl)-3-(morpholin-4-yl)-1H-pyrrole-2,5-dione
CAS 726200-79-9C16H18N2O3
3-Chloro-1-(4-ethylphenyl)-4-morpholin-4-ylpyrrole-2,5-dione chemical structure, C16H17ClN2O3, CAS 369395-63-1
3-Chloro-1-(4-ethylphenyl)-4-morpholin-4-ylpyrrole-2,5-dione
CAS 369395-63-1C16H17ClN2O3
3-Chloro-4-(morpholin-4-yl)-1-[4-(trifluoromethyl)phenyl]-2,5-dihydro-1H-pyrrole-2,5-dione chemical structure, C15H12ClF3N2O3, CAS 958732-63-3
3-Chloro-4-(morpholin-4-yl)-1-[4-(trifluoromethyl)phenyl]-2,5-dihydro-1H-pyrrole-2,5-dione
CAS 958732-63-3C15H12ClF3N2O3
4-(3-Chloro-4-morpholin-4-yl-2,5-dioxopyrrol-1-yl)benzenesulfonamide chemical structure, C14H14ClN3O5S, CAS 2117992-99-9
4-(3-Chloro-4-morpholin-4-yl-2,5-dioxopyrrol-1-yl)benzenesulfonamide
CAS 2117992-99-9C14H14ClN3O5S
3-Chloro-1-[4-(dimethylamino)phenyl]-4-morpholin-4-ylpyrrole-2,5-dione chemical structure, C16H18ClN3O3, CAS 2117996-80-0
3-Chloro-1-[4-(dimethylamino)phenyl]-4-morpholin-4-ylpyrrole-2,5-dione
CAS 2117996-80-0C16H18ClN3O3
N-[3-(3-Chloro-4-morpholin-4-yl-2,5-dioxopyrrol-1-yl)phenyl]acetamide chemical structure, C16H16ClN3O4, CAS 2117998-37-3
N-[3-(3-Chloro-4-morpholin-4-yl-2,5-dioxopyrrol-1-yl)phenyl]acetamide
CAS 2117998-37-3C16H16ClN3O4
3-Chloro-1-[3-(dimethylamino)phenyl]-4-morpholin-4-ylpyrrole-2,5-dione chemical structure, C16H18ClN3O3, CAS 2118050-02-3
3-Chloro-1-[3-(dimethylamino)phenyl]-4-morpholin-4-ylpyrrole-2,5-dione
CAS 2118050-02-3C16H18ClN3O3