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Murcko scaffold

4-(4-Phenyl-1-piperazinyl)thieno[2,3-d]pyrimidine scaffold

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
12
With full pages
0
Scaffold SMILES

c1ccc(N2CCN(c3ncnc4sccc34)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(4-Phenyl-1-piperazinyl)thieno[2,3-d]pyrimidine page
Murcko scaffold c1ccc(N2CCN(c3ncnc4sccc34)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

5,6-Dimethyl-4-(4-phenylpiperazin-1-yl)thieno[2,3-d]pyrimidine chemical structure, C18H20N4S, CAS 327971-27-7
5,6-Dimethyl-4-(4-phenylpiperazin-1-yl)thieno[2,3-d]pyrimidine
CAS 327971-27-7C18H20N4S
6-Methyl-4-(4-phenyl-1-piperazinyl)thieno[2,3-d]pyrimidine chemical structure, C17H18N4S, CAS 452087-36-4
6-Methyl-4-(4-phenyl-1-piperazinyl)thieno[2,3-d]pyrimidine
CAS 452087-36-4C17H18N4S
5,6-Dimethyl-4-[4-(4-methylphenyl)piperazin-1-yl]thieno[2,3-d]pyrimidine chemical structure, C19H22N4S, CAS 708250-05-9
5,6-Dimethyl-4-[4-(4-methylphenyl)piperazin-1-yl]thieno[2,3-d]pyrimidine
CAS 708250-05-9C19H22N4S
5,6-Dimethyl-4-[4-(2-methylphenyl)piperazin-1-yl]thieno[2,3-d]pyrimidine chemical structure, C19H22N4S, CAS 848740-70-5
5,6-Dimethyl-4-[4-(2-methylphenyl)piperazin-1-yl]thieno[2,3-d]pyrimidine
CAS 848740-70-5C19H22N4S
4-[4-(3,4-Dichlorophenyl)piperazin-1-yl]-5,6-dimethylthieno[2,3-d]pyrimidine chemical structure, C18H18Cl2N4S, CAS 315685-75-7
4-[4-(3,4-Dichlorophenyl)piperazin-1-yl]-5,6-dimethylthieno[2,3-d]pyrimidine
CAS 315685-75-7C18H18Cl2N4S
5,6-Dimethyl-4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]thieno[2,3-d]pyrimidine chemical structure, C19H19F3N4S, CAS 315685-42-8
5,6-Dimethyl-4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]thieno[2,3-d]pyrimidine
CAS 315685-42-8C19H19F3N4S
1-{5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl}-4-(2-methoxyphenyl)piperazine chemical structure, C19H22N4OS, CAS 315685-76-8
1-{5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl}-4-(2-methoxyphenyl)piperazine
CAS 315685-76-8C19H22N4OS
4-[4-(4-Methoxyphenyl)piperazin-1-yl]-5,6-dimethylthieno[2,3-d]pyrimidine chemical structure, C19H22N4OS, CAS 423145-30-6
4-[4-(4-Methoxyphenyl)piperazin-1-yl]-5,6-dimethylthieno[2,3-d]pyrimidine
CAS 423145-30-6C19H22N4OS
4-(4-Phenyl-1-piperazinyl)thieno[2,3-d]pyrimidine chemical structure, C16H16N4S, CAS 749870-28-8
4-(4-Phenyl-1-piperazinyl)thieno[2,3-d]pyrimidine
CAS 749870-28-8C16H16N4S
4-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)thieno[2,3-d]pyrimidine chemical structure, C17H15F3N4S, CAS 851789-97-4
4-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)thieno[2,3-d]pyrimidine
CAS 851789-97-4C17H15F3N4S
6-Methyl-4-(4-phenyl-1-piperazinyl)thieno[2,3-d]pyrimidine hydrochloride chemical structure, C17H19ClN4S
6-Methyl-4-(4-phenyl-1-piperazinyl)thieno[2,3-d]pyrimidine hydrochloride
C17H19ClN4S
4-(4-{Thieno[2,3-d]pyrimidin-4-yl}piperazin-1-yl)benzene-1-sulfonamide chemical structure, C16H17N5O2S2, CAS 3054588-58-5
4-(4-{Thieno[2,3-d]pyrimidin-4-yl}piperazin-1-yl)benzene-1-sulfonamide
CAS 3054588-58-5C16H17N5O2S2