CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 14 atoms

14 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
14
With full pages
3
Scaffold SMILES

O=C(Cc1ncc[nH]1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ncc[nH]1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

2-(1-Methyl-1H-imidazol-2-yl)-1-phenylethanone chemical structure, C12H12N2O, CAS 52083-24-6
2-(1-Methyl-1H-imidazol-2-yl)-1-phenylethanone
CAS 52083-24-6C12H12N2O
2-[1-(Difluoromethyl)-1H-imidazol-2-yl]-1-phenylethan-1-one hydrochloride chemical structure, C12H11ClF2N2O, CAS 1170005-86-3
2-[1-(Difluoromethyl)-1H-imidazol-2-yl]-1-phenylethan-1-one hydrochloride
CAS 1170005-86-3C12H11ClF2N2O
Ethanone, 1-(4-chlorophenyl)-2-(1-methyl-1H-imidazol-2-yl)- chemical structure, C12H11ClN2O, CAS 56923-88-7
Ethanone, 1-(4-chlorophenyl)-2-(1-methyl-1H-imidazol-2-yl)-
CAS 56923-88-7C12H11ClN2O
1-(2,4-Dichlorophenyl)-2-(1H-imidazol-2-yl)ethanone chemical structure, C11H8Cl2N2O, CAS 252950-14-4
1-(2,4-Dichlorophenyl)-2-(1H-imidazol-2-yl)ethanone
CAS 252950-14-4C11H8Cl2N2O
1-(2,4-Dichlorophenyl)-2-(4-methylimidazol-2-yl)ethan-1-one chemical structure, C12H10Cl2N2O, CAS 252953-85-8
1-(2,4-Dichlorophenyl)-2-(4-methylimidazol-2-yl)ethan-1-one
CAS 252953-85-8C12H10Cl2N2O
2-(1H-Imidazol-2-yl)-1-phenylethan-1-one hydrochloride chemical structure, C11H11ClN2O, CAS 52855-75-1
2-(1H-Imidazol-2-yl)-1-phenylethan-1-one hydrochloride
CAS 52855-75-1C11H11ClN2O
2-(4-Ethyl-5-methyl-1H-imidazol-2-yl)-1-phenylethanone chemical structure, C14H16N2O, CAS 774178-19-7
2-(4-Ethyl-5-methyl-1H-imidazol-2-yl)-1-phenylethanone
CAS 774178-19-7C14H16N2O
1-(4-Chloro-2-fluorophenyl)-2-(1H-imidazol-2-yl)ethan-1-one chemical structure, C11H8ClFN2O, CAS 1094763-06-0
1-(4-Chloro-2-fluorophenyl)-2-(1H-imidazol-2-yl)ethan-1-one
CAS 1094763-06-0C11H8ClFN2O
2-(1H-Imidazol-2-yl)-1-(3-methylphenyl)ethan-1-one hydrochloride chemical structure, C12H13ClN2O, CAS 1197539-31-3
2-(1H-Imidazol-2-yl)-1-(3-methylphenyl)ethan-1-one hydrochloride
CAS 1197539-31-3C12H13ClN2O
2-(1H-Imidazol-2-yl)-1-(3-methoxyphenyl)ethan-1-one hydrochloride chemical structure, C12H13ClN2O2, CAS 1209774-76-4
2-(1H-Imidazol-2-yl)-1-(3-methoxyphenyl)ethan-1-one hydrochloride
CAS 1209774-76-4C12H13ClN2O2
2-(1H-Imidazol-2-yl)-1-(2-methylphenyl)ethan-1-one hydrochloride chemical structure, C12H13ClN2O, CAS 1252206-09-9
2-(1H-Imidazol-2-yl)-1-(2-methylphenyl)ethan-1-one hydrochloride
CAS 1252206-09-9C12H13ClN2O
2-(1H-Imidazol-2-yl)-1-(4-methylphenyl)ethan-1-one hydrochloride chemical structure, C12H13ClN2O, CAS 52855-77-3
2-(1H-Imidazol-2-yl)-1-(4-methylphenyl)ethan-1-one hydrochloride
CAS 52855-77-3C12H13ClN2O
2-(1-Methyl-1H-imidazol-2-yl)-1-phenyl-ethanone hydrochloride chemical structure, C12H13ClN2O, CAS 1263378-50-2
2-(1-Methyl-1H-imidazol-2-yl)-1-phenyl-ethanone hydrochloride
CAS 1263378-50-2C12H13ClN2O
1-(2-Fluoro-4-methoxyphenyl)-2-(1-propyl-1H-imidazol-2-yl)ethan-1-one chemical structure, C15H17FN2O2, CAS 1519567-22-6
1-(2-Fluoro-4-methoxyphenyl)-2-(1-propyl-1H-imidazol-2-yl)ethan-1-one
CAS 1519567-22-6C15H17FN2O2