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Murcko scaffold

1,2-Benzisothiazol-3(2H)-one scaffold

154 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
154
With full pages
18
Scaffold SMILES

O=c1[nH]sc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2-Benzisothiazol-3(2H)-one page
Murcko scaffold O=c1[nH]sc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 154 chemicals

Ticlatone chemical structure, C7H4ClNOS, CAS 70-10-0
Ticlatone
CAS 70-10-0C7H4ClNOS
1,2-Benzisothiazol-3(2H)-one chemical structure, C7H5NOS, CAS 2634-33-5
1,2-Benzisothiazol-3(2H)-one
CAS 2634-33-5C7H5NOS
5-Chloro-1,2-benzisothiazolin-3-one chemical structure, C7H4ClNOS, CAS 4337-43-3
5-Chloro-1,2-benzisothiazolin-3-one
CAS 4337-43-3C7H4ClNOS
2-(3-(Dimethylamino)propyl)-1,2-benzisothiazol-3(2H)-one chemical structure, C12H16N2OS, CAS 18339-14-5
2-(3-(Dimethylamino)propyl)-1,2-benzisothiazol-3(2H)-one
CAS 18339-14-5C12H16N2OS
1,2-Benzothiazolin-3-one, 6-methyl- chemical structure, C8H7NOS, CAS 4337-47-7
1,2-Benzothiazolin-3-one, 6-methyl-
CAS 4337-47-7C8H7NOS
1,2-Benzisothiazoline-2-carboxylic acid, 3-oxo-, ethyl ester chemical structure, C10H9NO3S, CAS 30757-70-1
1,2-Benzisothiazoline-2-carboxylic acid, 3-oxo-, ethyl ester
CAS 30757-70-1C10H9NO3S
Proxel HL chemical structure, C21H40N4O7S, CAS 80546-24-3
Proxel HL
CAS 80546-24-3C21H40N4O7S
1,2-Benzisothiazol-3(2H)-one, 6-nitro- chemical structure, C7H4N2O3S, CAS 4337-51-3
1,2-Benzisothiazol-3(2H)-one, 6-nitro-
CAS 4337-51-3C7H4N2O3S
2-Ethyl-1,2-benzothiazol-3-one chemical structure, C9H9NOS, CAS 4299-06-3
2-Ethyl-1,2-benzothiazol-3-one
CAS 4299-06-3C9H9NOS
2-Methyl-1,2-benzisothiazolin-3-one chemical structure, C8H7NOS, CAS 2527-66-4
2-Methyl-1,2-benzisothiazolin-3-one
CAS 2527-66-4C8H7NOS
N-(Hydroxymethyl)-1,2-benzisothiazolin-3-one chemical structure, C8H7NO2S, CAS 7035-94-1
N-(Hydroxymethyl)-1,2-benzisothiazolin-3-one
CAS 7035-94-1C8H7NO2S
N-(Hydroxyethyl)-1,2-benzisothiazolin-3-One chemical structure, C9H9NO2S, CAS 4299-09-6
N-(Hydroxyethyl)-1,2-benzisothiazolin-3-One
CAS 4299-09-6C9H9NO2S
N-(2-Hydroxypropyl)-1,2-benzisothiazolin-3-One chemical structure, C10H11NO2S, CAS 4299-13-2
N-(2-Hydroxypropyl)-1,2-benzisothiazolin-3-One
CAS 4299-13-2C10H11NO2S
(2S,3S)-3-Methyl-2-(3-oxo-1,2-benzothiazol-2(3H)-yl)pentanoic acid chemical structure, C13H15NO3S, CAS 177785-47-6
(2S,3S)-3-Methyl-2-(3-oxo-1,2-benzothiazol-2(3H)-yl)pentanoic acid
CAS 177785-47-6C13H15NO3S
4-(3-Oxo-2,3-dihydro-1,2-benzothiazol-2-yl)butanoic acid chemical structure, C11H11NO3S, CAS 89139-50-4
4-(3-Oxo-2,3-dihydro-1,2-benzothiazol-2-yl)butanoic acid
CAS 89139-50-4C11H11NO3S
Propylcarbamic acid 2-(3-oxo-1,2-benzisothiazol-2(3H)-yl)ethyl ester chemical structure, C13H16N2O3S, CAS 183136-05-2
Propylcarbamic acid 2-(3-oxo-1,2-benzisothiazol-2(3H)-yl)ethyl ester
CAS 183136-05-2C13H16N2O3S
Butylcarbamic acid 2-(3-oxo-1,2-benzisothiazol-2(3H)-yl)ethyl ester chemical structure, C14H18N2O3S, CAS 183136-09-6
Butylcarbamic acid 2-(3-oxo-1,2-benzisothiazol-2(3H)-yl)ethyl ester
CAS 183136-09-6C14H18N2O3S
Ethylcarbamic acid 2-(3-oxo-1,2-benzisothiazol-2(3H)-yl)ethyl ester chemical structure, C12H14N2O3S, CAS 183136-03-0
Ethylcarbamic acid 2-(3-oxo-1,2-benzisothiazol-2(3H)-yl)ethyl ester
CAS 183136-03-0C12H14N2O3S
Isopropylcarbamic acid 2-(3-oxo-1,2-benzisothiazol-2-yl)ethyl ester chemical structure, C13H16N2O3S, CAS 183136-07-4
Isopropylcarbamic acid 2-(3-oxo-1,2-benzisothiazol-2-yl)ethyl ester
CAS 183136-07-4C13H16N2O3S
(1,1-Dimethylethyl)carbamic acid 2-(3-oxo-1,2-benzisothiazol-2(3H)-yl)ethyl ester chemical structure, C14H18N2O3S, CAS 183136-12-1
(1,1-Dimethylethyl)carbamic acid 2-(3-oxo-1,2-benzisothiazol-2(3H)-yl)ethyl ester
CAS 183136-12-1C14H18N2O3S
4-Fluoro-2,3-dihydro-1,2-benzothiazol-3-one chemical structure, C7H4FNOS, CAS 159803-09-5
4-Fluoro-2,3-dihydro-1,2-benzothiazol-3-one
CAS 159803-09-5C7H4FNOS
5-Fluoro-1,2-benzothiazol-3-one chemical structure, C7H4FNOS, CAS 159803-10-8
5-Fluoro-1,2-benzothiazol-3-one
CAS 159803-10-8C7H4FNOS
6-Fluoro-1,2-benzothiazol-3(2H)-one chemical structure, C7H4FNOS, CAS 159803-11-9
6-Fluoro-1,2-benzothiazol-3(2H)-one
CAS 159803-11-9C7H4FNOS
7-Fluoro-1,2-benzothiazol-3-one chemical structure, C7H4FNOS, CAS 159803-13-1
7-Fluoro-1,2-benzothiazol-3-one
CAS 159803-13-1C7H4FNOS