CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 17 atoms

137 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
137
With full pages
10
Scaffold SMILES

O=S(=O)(C=Cc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(C=Cc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 137 chemicals

Benzene, 1-methyl-4-[2-(phenylsulfonyl)ethenyl]- chemical structure, C15H14O2S, CAS 101093-66-7
Benzene, 1-methyl-4-[2-(phenylsulfonyl)ethenyl]-
CAS 101093-66-7C15H14O2S
Benzene, [(1-bromo-2-phenylethenyl)sulfonyl]- chemical structure, C14H11BrO2S, CAS 62251-29-0
Benzene, [(1-bromo-2-phenylethenyl)sulfonyl]-
CAS 62251-29-0C14H11BrO2S
1-(2-Iodo-2-phenylethenyl)sulfonyl-4-methylbenzene chemical structure, C15H13IO2S
1-(2-Iodo-2-phenylethenyl)sulfonyl-4-methylbenzene
C15H13IO2S
(Z)-3-(2-Ethoxyphenyl)-2-(4-methylphenyl)sulfonylprop-2-enenitrile chemical structure, C18H17NO3S, CAS 16612-30-9
(Z)-3-(2-Ethoxyphenyl)-2-(4-methylphenyl)sulfonylprop-2-enenitrile
CAS 16612-30-9C18H17NO3S
(E)-2-(4-Chlorophenyl)sulfonyl-3-(4-fluorophenyl)prop-2-enenitrile chemical structure, C15H9ClFNO2S, CAS 691367-43-8
(E)-2-(4-Chlorophenyl)sulfonyl-3-(4-fluorophenyl)prop-2-enenitrile
CAS 691367-43-8C15H9ClFNO2S
Phenyl trans-Styryl Sulfone chemical structure, C14H12O2S, CAS 16212-06-9
Phenyl trans-Styryl Sulfone
CAS 16212-06-9C14H12O2S
3-(4-Chlorophenyl)-2-(phenylsulfonyl)-2-propenenitrile chemical structure, C15H10ClNO2S, CAS 129200-98-2
3-(4-Chlorophenyl)-2-(phenylsulfonyl)-2-propenenitrile
CAS 129200-98-2C15H10ClNO2S
1-Methyl-4-[(E)-2-phenylethenyl]sulfonylbenzene chemical structure, C15H14O2S, CAS 16212-08-1
1-Methyl-4-[(E)-2-phenylethenyl]sulfonylbenzene
CAS 16212-08-1C15H14O2S
1-Nitro-3-[(E)-2-phenylethenyl]sulfonylbenzene chemical structure, C14H11NO4S, CAS 86971-40-6
1-Nitro-3-[(E)-2-phenylethenyl]sulfonylbenzene
CAS 86971-40-6C14H11NO4S
(alpha-Chlorostyryl)4-methylphenyl sulfone chemical structure, C15H13ClO2S, CAS 460743-32-2
(alpha-Chlorostyryl)4-methylphenyl sulfone
CAS 460743-32-2C15H13ClO2S
1-Fluoro-2-phenylvinyl 4-methylphenyl sulfone chemical structure, C15H13FO2S, CAS 1070970-80-7
1-Fluoro-2-phenylvinyl 4-methylphenyl sulfone
CAS 1070970-80-7C15H13FO2S
(E)-2-(Benzenesulfonyl)-3-phenylprop-2-enenitrile chemical structure, C15H11NO2S, CAS 129200-96-0
(E)-2-(Benzenesulfonyl)-3-phenylprop-2-enenitrile
CAS 129200-96-0C15H11NO2S
(Z)-2-(Benzenesulfonyl)-3-[4-methoxy-3-(methoxymethyl)phenyl]prop-2-enenitrile chemical structure, C18H17NO4S, CAS 706772-59-0
(Z)-2-(Benzenesulfonyl)-3-[4-methoxy-3-(methoxymethyl)phenyl]prop-2-enenitrile
CAS 706772-59-0C18H17NO4S
3-(3,4-Dihydroxyphenyl)-2-(phenylsulfonyl)acrylonitrile chemical structure, C15H11NO4S, CAS 186582-02-5
3-(3,4-Dihydroxyphenyl)-2-(phenylsulfonyl)acrylonitrile
CAS 186582-02-5C15H11NO4S
2-Iodo-2-phenylvinyl 4-methylphenyl sulfone chemical structure, C15H13IO2S, CAS 22183-12-6
2-Iodo-2-phenylvinyl 4-methylphenyl sulfone
CAS 22183-12-6C15H13IO2S
1-(2-Iodo-2-phenyl-ethenyl)sulfonyl-4-methyl-benzene chemical structure, C15H13IO2S, CAS 56480-95-6
1-(2-Iodo-2-phenyl-ethenyl)sulfonyl-4-methyl-benzene
CAS 56480-95-6C15H13IO2S
(E)-3-(2,6-Dichlorophenyl)-2-(4-methylphenyl)sulfonylprop-2-enenitrile chemical structure, C16H11Cl2NO2S
(E)-3-(2,6-Dichlorophenyl)-2-(4-methylphenyl)sulfonylprop-2-enenitrile
C16H11Cl2NO2S
(E)-2-(Benzenesulfonyl)-3-(2-bromo-5-ethoxy-4-propan-2-yloxyphenyl)prop-2-enenitrile chemical structure, C20H20BrNO4S, CAS 701287-35-6
(E)-2-(Benzenesulfonyl)-3-(2-bromo-5-ethoxy-4-propan-2-yloxyphenyl)prop-2-enenitrile
CAS 701287-35-6C20H20BrNO4S
Methyl (E)-3-(4-chlorophenyl)-2-(4-methylphenyl)sulfonylprop-2-enoate chemical structure, C17H15ClO4S, CAS 147435-97-0
Methyl (E)-3-(4-chlorophenyl)-2-(4-methylphenyl)sulfonylprop-2-enoate
CAS 147435-97-0C17H15ClO4S
(E)-2-(Benzenesulfonyl)-3-(4-iodophenyl)prop-2-enenitrile chemical structure, C15H10INO2S, CAS 373616-19-4
(E)-2-(Benzenesulfonyl)-3-(4-iodophenyl)prop-2-enenitrile
CAS 373616-19-4C15H10INO2S
(Z)-1-Methyl-4-(2-phenylethenyl)sulphonylbenzene chemical structure, C15H14O2S, CAS 54897-33-5
(Z)-1-Methyl-4-(2-phenylethenyl)sulphonylbenzene
CAS 54897-33-5C15H14O2S
(Z)-3-(2,4-Dimethoxyphenyl)-2-(4-methylphenyl)sulfonylprop-2-enenitrile chemical structure, C18H17NO4S, CAS 531494-16-3
(Z)-3-(2,4-Dimethoxyphenyl)-2-(4-methylphenyl)sulfonylprop-2-enenitrile
CAS 531494-16-3C18H17NO4S
3-(3,5-Di-tert-butyl-4-hydroxyphenyl)-2-(phenylsulfonyl)acrylonitrile chemical structure, C23H27NO3S, CAS 170449-05-5
3-(3,5-Di-tert-butyl-4-hydroxyphenyl)-2-(phenylsulfonyl)acrylonitrile
CAS 170449-05-5C23H27NO3S
(E)-3-(4-Butoxy-3-methoxyphenyl)-2-(4-chlorophenyl)sulfonylprop-2-enenitrile chemical structure, C20H20ClNO4S, CAS 692751-05-6
(E)-3-(4-Butoxy-3-methoxyphenyl)-2-(4-chlorophenyl)sulfonylprop-2-enenitrile
CAS 692751-05-6C20H20ClNO4S