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Murcko scaffold

Ring system with 2 rings and 12 atoms

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
12
With full pages
4
Scaffold SMILES

O=C1CCCc2oc(=O)ccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCc2oc(=O)ccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

4,7,7-Trimethyl-7,8-dihydro-2H-chromene-2,5(6H)-dione chemical structure, C12H14O3, CAS 3265-69-8
4,7,7-Trimethyl-7,8-dihydro-2H-chromene-2,5(6H)-dione
CAS 3265-69-8C12H14O3
2H-1-Benzopyran-2,5(6H)-dione, 3-amino-7,8-dihydro-7,7-dimethyl- chemical structure, C11H13NO3, CAS 128398-41-4
2H-1-Benzopyran-2,5(6H)-dione, 3-amino-7,8-dihydro-7,7-dimethyl-
CAS 128398-41-4C11H13NO3
7,8-Dihydro-4-methyl-2H-1-benzopyran-2,5(6H)-dione chemical structure, C10H10O3, CAS 3265-68-7
7,8-Dihydro-4-methyl-2H-1-benzopyran-2,5(6H)-dione
CAS 3265-68-7C10H10O3
Methyl 2,5-dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carboxylate chemical structure, C11H10O5, CAS 77959-75-2
Methyl 2,5-dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carboxylate
CAS 77959-75-2C11H10O5
Ethyl 7,7-dimethyl-2,5-dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carboxylate chemical structure, C14H16O5, CAS 77959-77-4
Ethyl 7,7-dimethyl-2,5-dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carboxylate
CAS 77959-77-4C14H16O5
2,5-Dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carboxamide chemical structure, C10H9NO4, CAS 85831-03-4
2,5-Dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carboxamide
CAS 85831-03-4C10H9NO4
7,7-Dimethyl-2,5-dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carbonitrile chemical structure, C12H11NO3, CAS 85831-04-5
7,7-Dimethyl-2,5-dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carbonitrile
CAS 85831-04-5C12H11NO3
Ethyl 2,5-dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carboxylate chemical structure, C12H12O5, CAS 1646839-55-5
Ethyl 2,5-dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carboxylate
CAS 1646839-55-5C12H12O5
2,5-Dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carbonitrile chemical structure, C10H7NO3, CAS 169777-55-3
2,5-Dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carbonitrile
CAS 169777-55-3C10H7NO3
Ethyl 6,6-dimethyl-2,5-dioxo-7,8-dihydrochromene-3-carboxylate chemical structure, C14H16O5, CAS 2135645-66-6
Ethyl 6,6-dimethyl-2,5-dioxo-7,8-dihydrochromene-3-carboxylate
CAS 2135645-66-6C14H16O5
7,7-Dimethyl-2,5-dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carboxylic acid chemical structure, C12H12O5, CAS 2219331-49-2
7,7-Dimethyl-2,5-dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carboxylic acid
CAS 2219331-49-2C12H12O5
2,5-Dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carboxylic acid chemical structure, C10H8O5, CAS 2243506-89-8
2,5-Dioxo-5,6,7,8-tetrahydro-2H-chromene-3-carboxylic acid
CAS 2243506-89-8C10H8O5