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Murcko scaffold

Ring system with 3 rings and 25 atoms

29 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
29
With full pages
2
Scaffold SMILES

O=C(COc1cccc(NC(=O)c2ccccc2)c1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1cccc(NC(=O)c2ccccc2)c1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

N-[3-[2-(3,4-Dimethylphenyl)-2-oxoethoxy]phenyl]-4-methylbenzamide chemical structure, C24H23NO3, CAS 700850-18-6
N-[3-[2-(3,4-Dimethylphenyl)-2-oxoethoxy]phenyl]-4-methylbenzamide
CAS 700850-18-6C24H23NO3
4-Bromo-N-[3-[2-(3,4-dimethylphenyl)-2-oxoethoxy]phenyl]benzamide chemical structure, C23H20BrNO3, CAS 695171-30-3
4-Bromo-N-[3-[2-(3,4-dimethylphenyl)-2-oxoethoxy]phenyl]benzamide
CAS 695171-30-3C23H20BrNO3
2-Chloro-N-[3-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]benzamide chemical structure, C22H18ClNO4, CAS 700855-58-9
2-Chloro-N-[3-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]benzamide
CAS 700855-58-9C22H18ClNO4
3,4-Dichloro-N-[3-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]benzamide chemical structure, C22H17Cl2NO4, CAS 700857-98-3
3,4-Dichloro-N-[3-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]benzamide
CAS 700857-98-3C22H17Cl2NO4
4-Bromo-N-[3-[2-(4-fluorophenyl)-2-oxoethoxy]phenyl]benzamide chemical structure, C21H15BrFNO3, CAS 701223-84-9
4-Bromo-N-[3-[2-(4-fluorophenyl)-2-oxoethoxy]phenyl]benzamide
CAS 701223-84-9C21H15BrFNO3
2-Chloro-N-[3-[2-(4-fluorophenyl)-2-oxoethoxy]phenyl]benzamide chemical structure, C21H15ClFNO3, CAS 701218-32-8
2-Chloro-N-[3-[2-(4-fluorophenyl)-2-oxoethoxy]phenyl]benzamide
CAS 701218-32-8C21H15ClFNO3
N-[3-[2-(4-Fluorophenyl)-2-oxoethoxy]phenyl]-2-methylbenzamide chemical structure, C22H18FNO3, CAS 700858-93-1
N-[3-[2-(4-Fluorophenyl)-2-oxoethoxy]phenyl]-2-methylbenzamide
CAS 700858-93-1C22H18FNO3
N-[3-[2-(4-Fluorophenyl)-2-oxoethoxy]phenyl]-3-methoxybenzamide chemical structure, C22H18FNO4, CAS 701224-66-0
N-[3-[2-(4-Fluorophenyl)-2-oxoethoxy]phenyl]-3-methoxybenzamide
CAS 701224-66-0C22H18FNO4
4-Bromo-N-[3-[2-(4-methoxyphenyl)-2-oxoethoxy]phenyl]benzamide chemical structure, C22H18BrNO4, CAS 700860-49-7
4-Bromo-N-[3-[2-(4-methoxyphenyl)-2-oxoethoxy]phenyl]benzamide
CAS 700860-49-7C22H18BrNO4
N-[3-[2-(4-Methoxyphenyl)-2-oxoethoxy]phenyl]-2-methylbenzamide chemical structure, C23H21NO4, CAS 695176-87-5
N-[3-[2-(4-Methoxyphenyl)-2-oxoethoxy]phenyl]-2-methylbenzamide
CAS 695176-87-5C23H21NO4
3,4-Dichloro-N-{3-[2-(4-methoxyphenyl)-2-oxoethoxy]phenyl}benzamide chemical structure, C22H17Cl2NO4, CAS 774187-23-4
3,4-Dichloro-N-{3-[2-(4-methoxyphenyl)-2-oxoethoxy]phenyl}benzamide
CAS 774187-23-4C22H17Cl2NO4
3-Methoxy-N-(3-phenacyloxyphenyl)benzamide chemical structure, C22H19NO4, CAS 695172-99-7
3-Methoxy-N-(3-phenacyloxyphenyl)benzamide
CAS 695172-99-7C22H19NO4
N-{3-[2-(3-Methoxyphenyl)-2-oxoethoxy]phenyl}-3-nitrobenzamide chemical structure, C22H18N2O6, CAS 695175-02-1
N-{3-[2-(3-Methoxyphenyl)-2-oxoethoxy]phenyl}-3-nitrobenzamide
CAS 695175-02-1C22H18N2O6
2-Chloro-N-[3-[2-(4-methoxyphenyl)-2-oxoethoxy]phenyl]benzamide chemical structure, C22H18ClNO4, CAS 695175-40-7
2-Chloro-N-[3-[2-(4-methoxyphenyl)-2-oxoethoxy]phenyl]benzamide
CAS 695175-40-7C22H18ClNO4
2,4-Dichloro-N-[3-[2-(3,4-dimethylphenyl)-2-oxoethoxy]phenyl]benzamide chemical structure, C23H19Cl2NO3, CAS 695171-05-2
2,4-Dichloro-N-[3-[2-(3,4-dimethylphenyl)-2-oxoethoxy]phenyl]benzamide
CAS 695171-05-2C23H19Cl2NO3
4-Chloro-N-(3-phenacyloxyphenyl)benzamide chemical structure, C21H16ClNO3, CAS 695174-31-3
4-Chloro-N-(3-phenacyloxyphenyl)benzamide
CAS 695174-31-3C21H16ClNO3
N-[3-[2-(3-Methoxyphenyl)-2-oxoethoxy]phenyl]-2-methylbenzamide chemical structure, C23H21NO4, CAS 695174-70-0
N-[3-[2-(3-Methoxyphenyl)-2-oxoethoxy]phenyl]-2-methylbenzamide
CAS 695174-70-0C23H21NO4
4-Bromo-N-[3-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]benzamide chemical structure, C22H18BrNO4, CAS 701222-71-1
4-Bromo-N-[3-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]benzamide
CAS 701222-71-1C22H18BrNO4
N-[3-(1-Benzoylpropoxy)phenyl]-4-bromobenzamide chemical structure, C23H20BrNO3, CAS 695172-43-1
N-[3-(1-Benzoylpropoxy)phenyl]-4-bromobenzamide
CAS 695172-43-1C23H20BrNO3
2-Chloro-N-[3-[1-(4-chlorophenyl)-1-oxopropan-2-yl]oxyphenyl]benzamide chemical structure, C22H17Cl2NO3, CAS 695173-22-9
2-Chloro-N-[3-[1-(4-chlorophenyl)-1-oxopropan-2-yl]oxyphenyl]benzamide
CAS 695173-22-9C22H17Cl2NO3
4-Bromo-N-[3-[1-(3-chlorophenyl)-1-oxopropan-2-yl]oxyphenyl]benzamide chemical structure, C22H17BrClNO3, CAS 695173-83-2
4-Bromo-N-[3-[1-(3-chlorophenyl)-1-oxopropan-2-yl]oxyphenyl]benzamide
CAS 695173-83-2C22H17BrClNO3
N-[3-[1-(4-Methoxyphenyl)-1-oxopropan-2-yl]oxyphenyl]-4-nitrobenzamide chemical structure, C23H20N2O6, CAS 695175-61-2
N-[3-[1-(4-Methoxyphenyl)-1-oxopropan-2-yl]oxyphenyl]-4-nitrobenzamide
CAS 695175-61-2C23H20N2O6
2-Methyl-N-[3-(1-oxo-1-phenylpropan-2-yl)oxyphenyl]benzamide chemical structure, C23H21NO3, CAS 700849-79-2
2-Methyl-N-[3-(1-oxo-1-phenylpropan-2-yl)oxyphenyl]benzamide
CAS 700849-79-2C23H21NO3
N-[3-[1-(3-Chlorophenyl)-1-oxopropan-2-yl]oxyphenyl]-3-methoxybenzamide chemical structure, C23H20ClNO4, CAS 700852-56-8
N-[3-[1-(3-Chlorophenyl)-1-oxopropan-2-yl]oxyphenyl]-3-methoxybenzamide
CAS 700852-56-8C23H20ClNO4