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Murcko scaffold

Ring system with 3 rings and 24 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
10
With full pages
2
Scaffold SMILES

O=C(NCc1ccccc1)c1cccc(COc2ccccc2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1ccccc1)c1cccc(COc2ccccc2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-Benzyl-3-[(4-chlorophenoxy)methyl]benzamide chemical structure, C21H18ClNO2, CAS 444998-24-7
N-Benzyl-3-[(4-chlorophenoxy)methyl]benzamide
CAS 444998-24-7C21H18ClNO2
N-Benzyl-3-[(3-chlorophenoxy)methyl]benzamide chemical structure, C21H18ClNO2, CAS 445006-82-6
N-Benzyl-3-[(3-chlorophenoxy)methyl]benzamide
CAS 445006-82-6C21H18ClNO2
3-[(4-Bromophenoxy)methyl]-N-(3,5-dimethoxybenzyl)benzamide chemical structure, C23H22BrNO4, CAS 495395-63-6
3-[(4-Bromophenoxy)methyl]-N-(3,5-dimethoxybenzyl)benzamide
CAS 495395-63-6C23H22BrNO4
3-[(4-Chlorophenoxy)methyl]-N-[1-(4-isopropylphenyl)propyl]benzamide chemical structure, C26H28ClNO2, CAS 438231-39-1
3-[(4-Chlorophenoxy)methyl]-N-[1-(4-isopropylphenyl)propyl]benzamide
CAS 438231-39-1C26H28ClNO2
3-[(4-Bromophenoxy)methyl]-N-[1-(4-tert-butylphenyl)ethyl]benzamide chemical structure, C26H28BrNO2, CAS 512825-18-2
3-[(4-Bromophenoxy)methyl]-N-[1-(4-tert-butylphenyl)ethyl]benzamide
CAS 512825-18-2C26H28BrNO2
3-[(2-Chlorophenoxy)methyl]-N-[1-(4-isopropylphenyl)propyl]-4-methoxybenzamide chemical structure, C27H30ClNO3, CAS 438233-86-4
3-[(2-Chlorophenoxy)methyl]-N-[1-(4-isopropylphenyl)propyl]-4-methoxybenzamide
CAS 438233-86-4C27H30ClNO3
N-[1-(4-tert-Butylphenyl)ethyl]-3-[(2-chlorophenoxy)methyl]-4-methoxybenzamide chemical structure, C27H30ClNO3, CAS 512816-19-2
N-[1-(4-tert-Butylphenyl)ethyl]-3-[(2-chlorophenoxy)methyl]-4-methoxybenzamide
CAS 512816-19-2C27H30ClNO3
3-[(2,4-Dichlorophenoxy)methyl]-N-[1-(4-propan-2-ylphenyl)propyl]benzamide chemical structure, C26H27Cl2NO2, CAS 827588-00-1
3-[(2,4-Dichlorophenoxy)methyl]-N-[1-(4-propan-2-ylphenyl)propyl]benzamide
CAS 827588-00-1C26H27Cl2NO2
EP3 antagonist 5 chemical structure, C29H32FNO4, CAS 499147-44-3
EP3 antagonist 5
CAS 499147-44-3C29H32FNO4
EP3 antagonist 6 chemical structure, C31H37NO4, CAS 499149-94-9
EP3 antagonist 6
CAS 499149-94-9C31H37NO4